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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2018-3-151-156</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-1294</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL PAPERS</subject></subj-group></article-categories><title-group><article-title>Роль гастроинтестинальной патологии в развитии и тяжести течения красного плоского лишая слизистой оболочки полости рта</article-title><trans-title-group xml:lang="en"><trans-title>The role of gastrointestinal pathology in the development and severity of oral lichen planus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5899-3872</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Титаренко</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Titarenko</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Титаренко Мария Александровна - аспирант, кафедра стоматологии.</p><p>634050, Томск, ул. Московский тракт, 2</p></bio><bio xml:lang="en"><p>Titarenko Maria A. - Post-graduate Student.</p></bio><email xlink:type="simple">mariatitarenko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6966-1323</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Столярова</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Stolyarova</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Столярова Валентина Александровна - кандидат медицинских наук, доцент, кафедра ýндокринологии.</p><p>634050, Томск, ул. Московский тракт, 2</p></bio><bio xml:lang="en"><p>Stolyarova Valentina A. - PhD, Associate Professor.</p><p>2, Moskow Tract, Tomsk, 634050</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4045-2664</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сысолятин</surname><given-names>П. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Sysolyatin</surname><given-names>P. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сысолятин Павел Гаврилович - докторр медицинских наук, профессор, заслуженный деятель науки РФ, кафедра госпитальной хирургической стоматологии и челюстно-лицевой хирургии.</p><p>630091, Новосибирск, Красный пр., 52</p></bio><bio xml:lang="en"><p>Sysolyatin Pavel G. - DM, Professor Honored Scientist of the Russian Federation.</p><p>52, Krasny Av., Novosibirsk, 630091</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4748-4175</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Байдик</surname><given-names>О. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Baydik</surname><given-names>O. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Байдик Ольга Дмитриевна - докторр медицинских наук, доцент, и.о. зав. кафедрой стоматологии.</p><p>634050, Томск, ул. Московский тракт, 2</p></bio><bio xml:lang="en"><p>Baydik Olga D. - DM, Associate Professor, SSMU, Tomsk, Russian Federation</p><p>2, Moskow Tract, Tomsk, 634050</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Сибирский государственный медицинский университет (СибГМУ)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Siberian State Medical University (SSMU)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Новосибирский государственный медицинский университет (НГМУ)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University (NSMU)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>29</day><month>09</month><year>2018</year></pub-date><volume>17</volume><issue>3</issue><fpage>151</fpage><lpage>156</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Титаренко М.А., Столярова В.А., Сысолятин П.Г., Байдик О.Д., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Титаренко М.А., Столярова В.А., Сысолятин П.Г., Байдик О.Д.</copyright-holder><copyright-holder xml:lang="en">Titarenko M.A., Stolyarova V.A., Sysolyatin P.G., Baydik O.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/1294">https://bulletin.ssmu.ru/jour/article/view/1294</self-uri><abstract><sec><title>Цель</title><p>Цель. При помощи дискриминантного анализа установить наиболее значимые предикторы красного плоского лишая слизистой оболочки полости рта у пациентов с гастроинтестинальной патологией.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование было включено 40 пациентов 41–86 лет с диагнозом «красный плоский лишай слизистой оболочки полости рта». Оценена степень тяжести красного плоского лишая слизистой оболочки полости рта, установлена сопутствующая патология желудочно-кишечного тракта. Обработка полученных результатов осуществлена с помощью дискриминантного анализа.</p></sec><sec><title>Результаты</title><p>Результаты. Выявлены наиболее значимые предикторы красного плоского лишая слизистой оболочки полости рта на фоне гастроинтестинальной патологии. Чувствительность метода составила 100,0%, специфичность – 100,0%, безошибочность – 100,0%.</p></sec><sec><title>Заключение</title><p>Заключение. Дискриминантный анализ позволяет провести достаточно точную диагностику красного плоского лишая слизистой оболочки полости рта на фоне гастроинтестинальной патологии. Полученная модель доступна в клинической практике.</p></sec></abstract><trans-abstract xml:lang="en"><p>The aim is to determine the most significant predictors of the oral lichen planus in patients with gastrointestinal pathology.</p><sec><title>Materials and methods</title><p>Materials and methods. The study was performed of 40 patients aged 41 to 86 years with oral lichen planus. Degree of mucosal damage by oral lichen planus was evaluated. The concomitant pathology of the gastrointestinal tract was established. A discriminant analysis was carried out.</p></sec><sec><title>Results</title><p>Results. The most significant predictors for a diagnosis of oral lichen planus in patients with  gastrointestinal pathology are revealed. The sensitivity of the method was 100.0%, the specificity was 100.0%, and the errorfreeness was 100.0%.</p></sec><sec><title>The conclusion</title><p>The conclusion. Discriminant analysis allows us to conduct a diagnosis of the oral lichen planus in patients with gastrointestinal pathology. This model is available in clinical practice.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>математическая модель</kwd><kwd>диагностика</kwd><kwd>красный плоский лишай</kwd><kwd>слизистая оболочка полости рта</kwd><kwd>гастроинтестинальная патология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>mathematical model</kwd><kwd>diagnosis</kwd><kwd>lichen planus</kwd><kwd>oral mucosa</kwd><kwd>gastrointestinal pathology</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Alrashdan M.S., Cirillo N., Mccullough M. Oral lichen planus: a literature review and update. Arch. Dermatol. 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