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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2011-1-92-96</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-1322</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РЕЗУЛЬТАТЫ ИССЛЕДОВАНИЙ МОЛОДЫХ УЧЕНЫХ И СТУДЕНТОВ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>THE RESULTS OF YOUNG SCIENTISTS’ AND STUDENTS’ INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Влияние лечения тяжелой хронической обструктивной болезни легких тиотропия бромидом на коморбидные соматогенные тревожно-депрессивные расстройства</article-title><trans-title-group xml:lang="en"><trans-title>Dynamics of somatogenic comorbid anxiety-depressive disorders expression under the tiotropium bromide treatment influence</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федосенко</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedosenko</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Федосенко Сергей Вячеславович, аспирант кафедры госпитальной терапии с курсом физической реабилитации и спортивной медицины</p><p>тел.: 8-923-415-0005, 8 (382-2) 56-06-38</p></bio><email xlink:type="simple">s-fedosenko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кириллова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kirillova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кириллова Наталья Александровна, аспирант кафедры госпитальной терапии с курсом физической реабилитации и спортивной медицины </p><p>тел. 8-913-888-0637</p></bio><email xlink:type="simple">kirillova.natalya@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Сибирский государственный медицинский университет</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>28</day><month>02</month><year>2011</year></pub-date><volume>10</volume><issue>1</issue><fpage>92</fpage><lpage>96</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Федосенко С.В., Кириллова Н.А., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Федосенко С.В., Кириллова Н.А.</copyright-holder><copyright-holder xml:lang="en">Fedosenko S.V., Kirillova N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/1322">https://bulletin.ssmu.ru/jour/article/view/1322</self-uri><abstract><p>С целью оценить динамику тревоги и депрессии у больных стабильной хронической обструктивной болезнью легких на фоне лечения тиотропия бромидом по опроснику HADS обследовано 30 больных, не получавших поддерживающей терапии, и 27 пациентов, применявших комбинацию флутиказона и сальметерола. Через 3 мес лечения тиотропия бромидом в обеих группах уровень тревоги и депрессии уменьшился.</p></abstract><trans-abstract xml:lang="en"><p>The aim of comparative research was the estimation of alarm and depression dynamics at patients with stable chronic obstructive pulmonary disease under influence of tiotropium treatment on HADS questionnaire. Are surveyed 30 patients who were not receiving supporting therapy and 27 patients, using a fluticasone/salmeterol combination. After 3 months of tiotropium treatment the level of alarm and depression decreased in both groups.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>тиотропия бромид</kwd><kwd>ХОБЛ</kwd><kwd>тревога</kwd><kwd>депрессия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>tiotropium bromide</kwd><kwd>COPD</kwd><kwd>alarm</kwd><kwd>depression</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена при частичной финансовой поддержке ФЦП «Научные и научно-педагогические кадры инновационной России» на 2009-2013 годы в рамках мероприятия 1.1 по направлению «Проведение научных исследований научно-образовательных центров в области биомедицинских и ветеринарных технологий жизнеобеспечения и защиты человека и животных» (ГК № 02.740.11.0083).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bratås O., Espnes G.A., Rannestad T. et al. 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