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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2011-1-162-167</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-1343</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОТ НАУКИ К ПРАКТИКЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>FROM SCIENCE TO PRACTICE</subject></subj-group></article-categories><title-group><article-title>Клинические аспекты патогенетических влияний, определяющих состояние иммунной системы у пациентов с ургентной хирургической патологией</article-title><trans-title-group xml:lang="en"><trans-title>Clinical aspects of pathogenetic influences defining the immune response in patients with urgent surgical pathology</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сарап</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sarap</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сарап Павел Владимирович, канд. мед. наук, врач аллерголог-иммунолог, зав. отделением переливания крови </p><p>тел. 8-960-758-40-98</p></bio><email xlink:type="simple">mssgbox@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Винник</surname><given-names>Ю. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Vinnik</surname><given-names>Yu. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, профессор, зав. кафедрой общей хирургии</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Останин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ostanin</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, профессор, главный науч. сотрудник лаборатории клеточной иммунотерапии</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>МУЗ «Городская клиническая больница № 6 им. Н.С. Карповича»</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Красноярский государственный медицинский университет</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>НИИ клинической иммунологии СО РАМН</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>28</day><month>02</month><year>2011</year></pub-date><volume>10</volume><issue>1</issue><fpage>162</fpage><lpage>167</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сарап П.В., Винник Ю.С., Останин А.А., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Сарап П.В., Винник Ю.С., Останин А.А.</copyright-holder><copyright-holder xml:lang="en">Sarap P.V., Vinnik Y.S., Ostanin A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/1343">https://bulletin.ssmu.ru/jour/article/view/1343</self-uri><abstract><p>Методами факторного анализа вычислены значения главных компонент (ГК), определяющих состояние различных звеньев иммунной системы у пациентов с ургентной хирургической патологией. Связи ГК с клиническими характеристиками пациентов характеризуют качественный состав факторов, влияющих на организацию показателей иммунной системы. Результаты исследования можно использовать для прогнозирования течения заболеваний и выбора эффективной тактики лечения.</p></abstract><trans-abstract xml:lang="en"><p>Using methods of factorial analysis the values of the main components (MC) defining a condition of various links of immune system in patients with urgent surgical pathology are calculated. MC interrelations with clinical characteristics describe qualitative structure of the factors influencing the organization of immune system indicators. Results of research can be used for forecasting of diseases current and a choice of effective tactics of treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ургентная хирургия</kwd><kwd>иммунитет</kwd><kwd>главные компоненты</kwd><kwd>факторный анализ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>urgent surgery</kwd><kwd>immunity</kwd><kwd>main components</kwd><kwd>factorial analysis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Fung Y.L., Fraser J.F., Wood P. etc. The systemic inflammatory response syndrome induces functional changes and relative hyporesponsiveness in neutrophils / J. Crit. Care. 2008. № 23 (4). P. 542—549.</mixed-citation><mixed-citation xml:lang="en">Fung Y.L., Fraser J.F., Wood P. etc. The systemic inflammatory response syndrome induces functional changes and relative hyporesponsiveness in neutrophils / J. Crit. Care. 2008. № 23 (4). 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