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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2014-6-81-92</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-155</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW AND LECTURES</subject></subj-group></article-categories><title-group><article-title>ЕДИНЫЙ АЛГОРИТМ ДЕЙСТВИЯ ГИПОЛИПИДЕМИЧЕСКИХ ПРЕПАРАТОВ. ОСНОВЫ ПЕРВИЧНОЙ ПРОФИЛАКТИКИ АТЕРОСКЛЕРОЗА, АТЕРОМАТОЗА И КОРОНАРНОГО СИНДРОМА</article-title><trans-title-group xml:lang="en"><trans-title>A SINGLE MECHANISM OF ACTION OF HYPOLIPIDEMIC DRUGS. BASIC PRINCIPLES OF PRIMARY PREVENTION OF ATHEROSCLEROSIS, ATHEROMATOSIS AND CORONARY SYNDROME</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Титов</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Titov</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Титов Владимир Николаевич – доктор медицинских наук, профессор, руководитель лаборатории клинической биохимии липидного обмена Института клинической кардиологии </p></bio><bio xml:lang="en"/><email xlink:type="simple">bolshakova_e_v@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котловский</surname><given-names>М. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotlovskiy</surname><given-names>M. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Котловский Михаил Юрьевич – кандидат медицинских наук, зав. отделом газожидкостной, жидкостной и времяпролетной масс-спектрометрии ЦНИЛ</p></bio><bio xml:lang="en"/><email xlink:type="simple">bolshakova_e_v@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Курдояк</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurdoyak</surname><given-names>Ye. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Курдояк Евгения Валентиновна – биолог лаборатории газожидкостной, жидкостной и времяпролетной масс-спектрометрии ЦНИЛ </p></bio><bio xml:lang="en"/><email xlink:type="simple">bolshakova_e_v@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Якименко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakimenko</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Якименко Анна Владимировна – биолог лаборатории газожидкостной, жидкостной и времяпролетной масс-спектрометрии ЦНИЛ </p></bio><bio xml:lang="en"/><email xlink:type="simple">bolshakova_e_v@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Якимович</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakimovich</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Якимович Инесса Юрьевна – кандидат медицинских наук, доцент кафедры физической культуры и здоровья СибГМУ Томск </p></bio><bio xml:lang="en"><p>Yakimovich Inessa Yu.</p></bio><email xlink:type="simple">bolshakova_e_v@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аксютина</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Aksyutina</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аксютина Наталья Валерьевна – кандидат медицинских наук</p></bio><bio xml:lang="en"/><email xlink:type="simple">bolshakova_e_v@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котловский</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotlovskiy</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Котловский Юрий Васильевич – доктор медицинских наук, профессор, зав. ЦНИЛ</p></bio><bio xml:lang="en"/><email xlink:type="simple">bolshakova_e_v@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дыгай</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Dygai</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дыгай Александр Михайлович– заслуженный деятель науки РФ, доктор медицинских наук, профессор, академик РАН, директор </p></bio><bio xml:lang="en"/><email xlink:type="simple">bolshakova_e_v@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский кардиологический научно-производственный комплекс Министерства здравоохранения РФ, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Cardiology Research-and-Production Center, Ministry of Health, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Сибирский государственный медицинский университет, Томск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>SiberianStateMedicalUniversity,Tomsk</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>НИИ фармакологии и регенеративной медицины имени Е.Д. Гольдберга, Томск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Pharmacology and Regenerative Medicine named after E.D. Goldberg, Tomsk</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2014</year></pub-date><volume>13</volume><issue>6</issue><fpage>81</fpage><lpage>92</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Титов В.Н., Котловский М.Ю., Курдояк Е.В., Якименко А.В., Якимович И.Ю., Аксютина Н.В., Котловский Ю.В., Дыгай А.М., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Титов В.Н., Котловский М.Ю., Курдояк Е.В., Якименко А.В., Якимович И.Ю., Аксютина Н.В., Котловский Ю.В., Дыгай А.М.</copyright-holder><copyright-holder xml:lang="en">Titov V.N., Kotlovskiy M.Y., Kurdoyak Y.V., Yakimenko A.V., Yakimovich I.Y., Aksyutina N.V., Kotlovskiy Y.V., Dygai A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/155">https://bulletin.ssmu.ru/jour/article/view/155</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>атеросклероз</kwd><kwd>гиполипидемические препараты</kwd><kwd>плейотропное действие</kwd><kwd>ги-перлипопротеинемия</kwd><kwd>никотиновая кислота</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atherosclerosis</kwd><kwd>hypolipidemic drugs</kwd><kwd>pleiotropic activity</kwd><kwd>hypolipoproteinemia</kwd><kwd>nicotinic acid</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Кухарук В.В. 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