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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2010-2-145-152</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-1583</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРИБЛИЖЕНИЕ К БИОУПРАВЛЕНИЮ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>APPROACH TO THE BIOFEEDBACK</subject></subj-group></article-categories><title-group><article-title>Изучение пространственно-временной структуры электроэнцефалографической активности для объективизации оценки индивидуальных особенностей цикла сон — бодрствование</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of spatio-temporal structure of EEG-activity to form an objective assessment of the individual characteristics of the sleep-wake behavior</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Путилов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Putilov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Путилов Аркадий Александрович, д-р биол. наук, ведущий научный сотрудник лаборатории математического моделирования биомедицинских систем </p><p>тел. (383) 335-97-56</p></bio><email xlink:type="simple">putilov@ngs.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Донская</surname><given-names>О. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Donskaya</surname><given-names>O. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>научный сотрудник лаборатории математического моделирования биомедицинских систем</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Верёвкин</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Veryovkin</surname><given-names>Ye. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. биол. наук, руководитель лаборатории математического моделирования биомедицинских систем</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Путилов</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Putilov</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант лаборатории математического моделирования биомедицинских систем</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>НИИ молекулярной биологии и биофизики СО РАМН</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2010</year></pub-date><volume>9</volume><issue>2</issue><fpage>145</fpage><lpage>152</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Путилов А.А., Донская О.Г., Верёвкин Е.Г., Путилов Д.А., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Путилов А.А., Донская О.Г., Верёвкин Е.Г., Путилов Д.А.</copyright-holder><copyright-holder xml:lang="en">Putilov A.A., Donskaya O.G., Veryovkin Y.G., Putilov D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/1583">https://bulletin.ssmu.ru/jour/article/view/1583</self-uri><abstract><p>Описана структура индивидуальной изменчивости электроэнцефалограммы (ЭЭГ) в процессе круглосуточного бодрствования 126 человек. Выявлены ее количественные связи с хронотипом (утренняя и вечерняя сонливость), сомнотипом (возможность уснуть в любое время) и трототипом (возможность бодрствовать в любое время суток). Обнаружено, что индивидуальные различия в чувствительности уровня бодрствования к лишению сна могут быть количественно предсказаны по структурным особенностям ЭЭГ как во время обычного дневного бодрствования, так и при депривации сна в ночные часы.</p></abstract><trans-abstract xml:lang="en"><p>The structure of individual variation in waking EEG was elaborated in 130 sleep deprived subjects. Its quantitative relationship with chronotype (morning and evening lateness), somnotype (daytime and anytime sleepability) and trototype (daytime and anytime wakeability) was described. The findings indicate that individual vulnerability of wakeability to sleep loss can serve as a quantitative predictor using the structures of waking EEG at daytime and during sleep deprivation.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>регуляция цикла сон — бодрствование</kwd><kwd>лишение сна</kwd><kwd>закономерности индивидуальной изменчивости</kwd><kwd>хронотип</kwd><kwd>сомнотип</kwd><kwd>трототип</kwd><kwd>электроэнцефалография бодрствования</kwd><kwd>альфа-активность</kwd><kwd>тета-активность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>regulation of the sleep-wake cycle</kwd><kwd>sleep deprivation</kwd><kwd>regularities of individual variability</kwd><kwd>chronotype</kwd><kwd>somnotype</kwd><kwd>trototype</kwd><kwd>waking EEG</kwd><kwd>alpha activity</kwd><kwd>theta activity</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследования выполнены при поддержке Российского гуманитарного научного фонда, грант № 06-06- 00375а, и Российского фонда фундаментальных исследований, гранты № 07-06-00263а и 10-06-00114.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Путилов А.А. 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