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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2010-5-5-12</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-1650</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКТОВАЯ ЛЕКЦИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ASSEMBLY LECTION</subject></subj-group></article-categories><title-group><article-title>Молекулярно-генетические факторы туберкулеза легких</article-title><trans-title-group xml:lang="en"><trans-title>Molecular-genetic factors of a pulmonary tuberculosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Уразова</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Urazova</surname><given-names>O. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Уразова Ольга Ивановна, д-р мед. наук, профессор кафедры патофизиологии </p><p>тел. 8-903-913-1483</p></bio><email xlink:type="simple">Urazova72@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Сибирский государственный медицинский университет</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>28</day><month>10</month><year>2010</year></pub-date><volume>9</volume><issue>5</issue><fpage>5</fpage><lpage>12</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Уразова О.И., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Уразова О.И.</copyright-holder><copyright-holder xml:lang="en">Urazova O.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/1650">https://bulletin.ssmu.ru/jour/article/view/1650</self-uri><abstract><p>В лекции анализируется модулирующее влияние возбудителя на характер иммунного ответа при туберкулезе легких. Обсуждаются особенности иммунопатологических реакций в зависимости от этиологического варианта заболевания и спектра бактериорезистентности к противотуберкулезным препаратам с обоснованием возможных подходов к их коррекции. Представлены основные направления научно-исследовательской работы кафедры патофизиологии Сибирского государственного медицинского университета (г. Томск) в области иммунопатологии туберкулезной инфекции.</p></abstract><trans-abstract xml:lang="en"><p>The modulating influence of a causative agent on the character of an immune reaction at lung tuberculosis is analyzed. Peculiarities of immunopathological reactions depending on the etiological version of a disease and the spectrum of bacterial resistance to antituberculous preparations are discussed with the justification of possible approaches to their correction. Main fields of research activity at the Chair of Pathophysiology of the Siberian State Medical University (Tomsk) concerning immunopathology of the tuberculosis infection are presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>туберкулез легких</kwd><kwd>иммунитет</kwd><kwd>лейкоциты</kwd><kwd>Mycobacterium tuberculosis</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pulmonary tuberculosis</kwd><kwd>immunity</kwd><kwd>leukocytes</kwd><kwd>Mycobacterium tuberculosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
