ssmuБюллетень сибирской медициныBulletin of Siberian Medicine1682-03631819-3684Siberian State Medical University, the Ministry of Healthcare of the Russian Federation10.20538/1682-0363-2010-6-160-164ssmu-1712Research ArticleДИСКУССИИDISCUSSIONSГазовая атака, или Осторожно, газы!Gas attack or gently, the gases!БаскаковМ. Б.BaskakovM. B.

Баскаков Михаил Борисович, д-р мед. наук, профессор, зав. кафедрой биофизики и функциональной диагностики 

тел. (3822) 42-09-54

baskakovmb@mail.ruЮсубовМ. С.YusubovM. S.

д-р хим. наук, профессор, зав. кафедрой химии

Сибирский государственный медицинский университетRussian FederationСибирский государственный медицинский университет; Национальный исследовательский Томский политехнический университетRussian Federation20102812201096160164Copyright © Баскаков М.Б., Юсубов М.С., 20102010Баскаков М.Б., Юсубов М.С.Baskakov M.B., Yusubov M.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://bulletin.ssmu.ru/jour/article/view/1712

В статье даются современные представления о газовой коммуникации в гладкомышечных клетках, рассмотрены основные механизмы действия газотрансмиттеров, анализируются различные взгляды на природу эндотелиального релаксирующего и эндотелиального гиперполяризующего факторов. Обсуждаются дискуссионные вопросы механизмов эндотелий-зависимого расслабления гладких мышц сосудов.

The article contains the current understanding of gas communication in smooth muscle cells, the basic mechanisms of action of gaseous transmitters, analyzes the different views on the nature of the endothelial relaxing and endothelial hyperpolarizing factors. We discuss the controversial issues of the mechanisms of endothelium-dependent relaxation of vascular smooth muscle.

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The authors declare that there are no conflicts of interest present.