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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2009-1-85-91</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-1750</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОТ НАУКИ К ПРАКТИКЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>FROM SCIENCE TO PRACTICE</subject></subj-group></article-categories><title-group><article-title>Эффективность хирургического лечения туберкулеза легких с множественной лекарственной устойчивостью в условиях программы DOTS-PLUS</article-title><trans-title-group xml:lang="en"><trans-title>Efficiency of surgical treatment of multidrug-resistant Pulmonary Tuberculosis within the DOTS-PLUS program</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стрелис</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Strelis</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>член корреспондент РАМН д р мед наук профессор зав кафедрой фтизиатрии и пульмонологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стрелис</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Strelis</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д р мед наук профессор кафедры фтизиатрии и пульмонологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анастасов</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Anastasov</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анастасов Олег Валерьевич, ассистент кафедры фтизиатрии и пульмонологии </p><p>(382-2) 91-13-75</p></bio><email xlink:type="simple">anastov80@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Некрасов</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nekrasov</surname><given-names>Ye. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд мед наук доцент кафедры фтизиатрии и пульмонологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Раскошных</surname><given-names>В. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Raskoshnykh</surname><given-names>V. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач высшей категории зав отделением легочной хирургии</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Задорожний</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Zadorozniy</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд мед наук ассистент кафедры фтизиатрии и пульмонологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Губин</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gubin</surname><given-names>Ye. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щегерцов</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Schegertzov</surname><given-names>D. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Христенко</surname><given-names>О. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Khristenko</surname><given-names>O. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Янова</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yanova</surname><given-names>G. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд мед наук главный врач</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Сибирский государственный медицинский университет</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Томская областная клиническая туберкулезная больница</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>Томский областной противотуберкулезный диспансер</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>28</day><month>02</month><year>2009</year></pub-date><volume>8</volume><issue>1</issue><fpage>85</fpage><lpage>91</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Стрелис А.К., Стрелис А.А., Анастасов О.В., Некрасов Е.В., Раскошных В.К., Задорожний А.И., Губин Е.А., Щегерцов Д.Ю., Христенко О.Ю., Янова Г.В., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Стрелис А.К., Стрелис А.А., Анастасов О.В., Некрасов Е.В., Раскошных В.К., Задорожний А.И., Губин Е.А., Щегерцов Д.Ю., Христенко О.Ю., Янова Г.В.</copyright-holder><copyright-holder xml:lang="en">Strelis A.K., Strelis A.A., Anastasov O.V., Nekrasov Y.V., Raskoshnykh V.K., Zadorozniy A.I., Gubin Y.A., Schegertzov D.Y., Khristenko O.Y., Yanova G.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/1750">https://bulletin.ssmu.ru/jour/article/view/1750</self-uri><abstract/><trans-abstract xml:lang="en"><p>Efficiency of the surgical treatment of pulmonary tuberculosis for multidrug-resistant (MDR TB) tuberculosis patients was analyzed. Seventy DOTS-PLUS patients with various clinical forms of pulmonary tuberculosis and Mycobacterium resistance from 3 to 8 antituberculosis drugs have been operated. Positive clinical results have been achieved for 65 (92,8%) patients. Indications for surgical treatment for patients with MDR TB have been developed. To ensure positive outcomes of the surgical interventions, main objective is the development of so-called a favorable preoperative environment during the preoperative phase. It includes switching on intensive chemotherapy and pathogenetic methods of treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>туберкулез легких</kwd><kwd>множественная лекарственная устойчивость</kwd><kwd>хирургическое лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pulmonary tuberculosis</kwd><kwd>multidrug resistance</kwd><kwd>surgical treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Залескис Р. Роль хирургических методов в лечении туберкулеза//Проблемы туберкулеза. 2001. № 9. С. 3-5</mixed-citation><mixed-citation xml:lang="en">Залескис Р. Роль хирургических методов в лечении туберкулеза//Проблемы туберкулеза. 2001. № 9. С. 3-5</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Краснов Д.В., Андренко А.А. и др. 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