ssmuБюллетень сибирской медициныBulletin of Siberian Medicine1682-03631819-3684Siberian State Medical University, the Ministry of Healthcare of the Russian Federation10.20538/1682-0363-2009-1(2)-23-26ssmu-1758Research ArticleЭКСПЕРИМЕНТАЛЬНЫЕ И КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯEXPERIMENTAL AND CLINICAL INVESTIGATIONSМолекулы адгезии и провоспалительные цитокины в спинномозговой жидкости больных рассеянным склерозомAdhesion molecules and proinflammatory cytokines in cerebrospinal fluid of multiple sclerosis patientsЕльчаниноваС. А.YelchaninovaS. A.

д р биол наук профессор зав кафедрой биохимии и клинической лабораторной диагностики

СмагинаИ. В.SmaginaI. V.

Смагина Инна Вадимовна, канд мед наук доцент невролог 

тел. 8-903-990-50-99

siv7000@yandex.ruСидоренкоВ. А.SidorenkoV. A.

ассистент кафеды биохимии и клинической лабораторной диагностики

ЛиченкоЮ. Н.LichenkoYu. N.

невролог

ПоповцеваА. В.PopovtsevaA. V.

ассистент кафедры биохимии и клинической лабораторной диагностики

ФедянинА. С.FedyaninA. S.

зав неврологическим отделением

главный внештатный невролог главного управления Алтайского края по здравоохранению и фармацевтической деятельности 

Алтайский государственный медицинский университетRussian FederationАлтайская краевая клиническая больницаRussian Federation20092802200981(2)2326Copyright © Ельчанинова С.А., Смагина И.В., Сидоренко В.А., Личенко Ю.Н., Поповцева А.В., Федянин А.С., 20092009Ельчанинова С.А., Смагина И.В., Сидоренко В.А., Личенко Ю.Н., Поповцева А.В., Федянин А.С.Yelchaninova S.A., Smagina I.V., Sidorenko V.A., Lichenko Y.N., Popovtseva A.V., Fedyanin A.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://bulletin.ssmu.ru/jour/article/view/1758

In liquor 30 multiple sclerosis patients with remittent kind of clinical course the concentration of cell-cell adhesion molecules (sPECAM-1, sVCAM-1) and tumor necrosis factor (TNF) α, not interleukin-1β, was higher during the period of exacerbation compared to the period of remission. These changes are supposed to display the activity of pathogenesis important processes multiple sclerosis in cerebral tissue of multiple sclerosis patients.

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The authors declare that there are no conflicts of interest present.