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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2009-2-61-68</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-1792</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКСПЕРИМЕНТАЛЬНЫЕ И КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERIMENTAL AND CLINICAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Значение исследования семейного анамнеза при антифосфолипидном синдроме</article-title><trans-title-group xml:lang="en"><trans-title>The role of family anamnesis investigation in antiphospholipid syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чапаева</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Chapayeva</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чапаева Наталья Николаевна, д р мед наук профессор кафедры госпитальной терапии и клинической фармакологии лечебного факультета</p><p>8-905-959-2655, 8-913-912-2345</p></bio><email xlink:type="simple">n.chapaeva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трифонова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Trifonova</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>клинический ординатор кафедры госпитальной терапии и клинической фармакологии лечебного факультета</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Новосибирский государственный медицинский университет</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2009</year></pub-date><volume>8</volume><issue>2</issue><fpage>61</fpage><lpage>68</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чапаева Н.Н., Трифонова М.А., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Чапаева Н.Н., Трифонова М.А.</copyright-holder><copyright-holder xml:lang="en">Chapayeva N.N., Trifonova M.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/1792">https://bulletin.ssmu.ru/jour/article/view/1792</self-uri><abstract/><trans-abstract xml:lang="en"><p>The investigation of 82 families of patients with antiphospholipid syndrome (APS) was performed. APS was diagnosed in 1st-degree relatives and woman more frequently. Minor features of APS were revealed in half of relatives, lupus anticoagulant (LA) — in a third of them. If person has APS in family anamnesis, minor features of APS or (and) LA, pre-APS can be diagnosed and primary prevention of thrombosis can be conducted.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>антифосфолипидный синдром</kwd><kwd>пре-АФС</kwd><kwd>семейный анамнез</kwd></kwd-group><kwd-group xml:lang="en"><kwd>antiphospholipid syndrome</kwd><kwd>pre-APS</kwd><kwd>family anamnesis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Воевода М.И., Максимов В.Н., Малютина С.К. Семейный анамнез и его связь с сердечно-сосудистыми заболеваниями в мужской популяции Новосибирска//Бюл. СО РАМН. 2006. Т. 4. № 122. 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