Seventy seven type 2 diabetes patients undergoing medical treatment in day hospital and specialized department have been examined. To assess the life quality, the SF-36 general questionnaire was used. One year later, the life quality of the patients was assessed repeatedly. The data obtained indicate that the life quality of type 2 diabetes patients is decreased in all indices compared to the common population. In hospital patients, the PF, PR, and RE indices were reliably decreased compared to day patients. It was found that the PF and RE indices reliably decrease with the years of disease. It was noticed that the compensation of carbohydrate metabolism influences positively the life quality of type 2 diabetes patients, and the reliable improvement was revealed in the PF index. Type 2 diabetes negatively affects the self-assessment of the life-quality of patients, significantly restricts the everyday physical activity, and weakens the vitality. As the term of the disease increases, such indices as physical activity amd emotional state worsen.