<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2009-2-113-117</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-1800</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОТ НАУКИ К ПРАКТИКЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>FROM SCIENCE TO PRACTICE</subject></subj-group></article-categories><title-group><article-title>Использование UBC-теста в качестве уринологического маркера рака мочевого пузыря</article-title><trans-title-group xml:lang="en"><trans-title>UBC-test use in the capacity of urinary marker of bladder cancer</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Винтизенко</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Vintizenko</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Винтизенко Станислав Игоревич, аспирант отделения общей онкологии</p><p>+7-913-811-1118</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Слонимская</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Slonimskaya</surname><given-names>Ye. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д р мед наук профессор руководитель отделения общей онкологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Усынин</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Usynin</surname><given-names>Ye. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд мед наук ст науч сотрудник отделения общей онкологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стуканов</surname><given-names>С. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Stukanov</surname><given-names>S. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд биол наук науч сотрудник отделения радионуклидной диагностики</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>НИИ онкологии СО РАМН</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2009</year></pub-date><volume>8</volume><issue>2</issue><fpage>113</fpage><lpage>117</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Винтизенко С.И., Слонимская Е.М., Усынин Е.А., Стуканов С.Л., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Винтизенко С.И., Слонимская Е.М., Усынин Е.А., Стуканов С.Л.</copyright-holder><copyright-holder xml:lang="en">Vintizenko S.I., Slonimskaya Y.M., Usynin Y.A., Stukanov S.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/1800">https://bulletin.ssmu.ru/jour/article/view/1800</self-uri><abstract/><trans-abstract xml:lang="en"><p>The enzyme immunoassay was used to evaluate diagnostic value of level of tumoral marker UBC at 54 patients with muscle invasive bladder cancer. The obtained data testify to possibility of use of the UBC-test for diagnostics primary bladder cancer, at monitoring for patients for revealing superficial and muscle invasive relapses after spent treatments. UBC it can be considered as the additional diagnostic marker, allowing to assume presence muscle invasive character of growth of a tumors, and also for an efficiency estimation neoadjuvant chemotherapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак</kwd><kwd>мочевой пузырь</kwd><kwd>опухолевый маркер UBC</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cancer</kwd><kwd>urinary bladder</kwd><kwd>tumor UBC marker</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Маршутина Н.В., Сергеева Н.С., Стороженко И.В. и др. Оценка новых опухолевых маркеров TAG12, CA242 и UBC у онкологических больных//Материалы 5-го Всерос. съезда онкологов. Казань, 2000. С. 190-191.</mixed-citation><mixed-citation xml:lang="en">Маршутина Н.В., Сергеева Н.С., Стороженко И.В. и др. Оценка новых опухолевых маркеров TAG12, CA242 и UBC у онкологических больных//Материалы 5-го Всерос. съезда онкологов. Казань, 2000. С. 190-191.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Матвеев Б.П., Фигурин К.М., Корякин О.Б. Рак мочевого пузыря. М., 2001. 243 c.</mixed-citation><mixed-citation xml:lang="en">Матвеев Б.П., Фигурин К.М., Корякин О.Б. Рак мочевого пузыря. М., 2001. 243 c.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Матвеенко А.А. Цитодиагностические критерии прогрессии рака мочевого пузыря//Материалы 5-го Всерос. съезда онкологов. Казань, 2000. С. 340-342.</mixed-citation><mixed-citation xml:lang="en">Матвеенко А.А. Цитодиагностические критерии прогрессии рака мочевого пузыря//Материалы 5-го Всерос. съезда онкологов. Казань, 2000. С. 340-342.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Мационис А.Э., Матвеенко А.А., Медведева Л.А., Ягубянц Ю.Т. Поверхностный рак мочевого пузыря. Роль патолога//Материалы 4-й Всерос. конф. М., 2001. С. 30-38.</mixed-citation><mixed-citation xml:lang="en">Мационис А.Э., Матвеенко А.А., Медведева Л.А., Ягубянц Ю.Т. Поверхностный рак мочевого пузыря. Роль патолога//Материалы 4-й Всерос. конф. М., 2001. С. 30-38.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Меньшиков В.В. Качество клинических лабораторных исследований. М.: Москва, 2002. 304 с.</mixed-citation><mixed-citation xml:lang="en">Меньшиков В.В. Качество клинических лабораторных исследований. М.: Москва, 2002. 304 с.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Переверзев А.С., Петров С.Б. Опухоли мочевого пузыря. Харьков: Факт, 2002. 303 с.</mixed-citation><mixed-citation xml:lang="en">Переверзев А.С., Петров С.Б. Опухоли мочевого пузыря. Харьков: Факт, 2002. 303 с.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Сергеева Н.С., Родина И.А., Русаков И.Г. и др. Исследование UBC-антигена как возможного уринологического маркера рака мочевого пузыря//Рос. онкол. журн. № 1. 2004. С. 30-33.</mixed-citation><mixed-citation xml:lang="en">Сергеева Н.С., Родина И.А., Русаков И.Г. и др. Исследование UBC-антигена как возможного уринологического маркера рака мочевого пузыря//Рос. онкол. журн. № 1. 2004. С. 30-33.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Шелепова В.М. Клиническое значение определения растворимого фрагмента цитокератина 19-Cyfra 21-1//Лаборатория. 2004. № 2. C. 3-6.</mixed-citation><mixed-citation xml:lang="en">Шелепова В.М. Клиническое значение определения растворимого фрагмента цитокератина 19-Cyfra 21-1//Лаборатория. 2004. № 2. C. 3-6.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Babjuk M., Kostirova M. and Mudra K. et al. Qualitative and quantitative detection of urinary human complement factor H-related protein (BTA stat and BTA TRAK) and fragments of cytokeratins 8, 18 (UBC rapid and UBC IRMA) as markers for transitional cell carcinoma of the bladder//Eur. Urol. 2002. № 41. P. 34-39.</mixed-citation><mixed-citation xml:lang="en">Babjuk M., Kostirova M. and Mudra K. et al. Qualitative and quantitative detection of urinary human complement factor H-related protein (BTA stat and BTA TRAK) and fragments of cytokeratins 8, 18 (UBC rapid and UBC IRMA) as markers for transitional cell carcinoma of the bladder//Eur. Urol. 2002. № 41. P. 34-39.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Вol M.G., Baak J.P., van Diermen B. et al. Proliferation markers and DNA content analysis in urinary bladder TaT1 urothelial cell carcinomfs: identification of subgroups with low and high stage progression risk//J. Clin. Pathol. 2003. V. 56. P. 447-452.</mixed-citation><mixed-citation xml:lang="en">Вol M.G., Baak J.P., van Diermen B. et al. Proliferation markers and DNA content analysis in urinary bladder TaT1 urothelial cell carcinomfs: identification of subgroups with low and high stage progression risk//J. Clin. Pathol. 2003. V. 56. P. 447-452.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Dai G., Wang X. Development of bladder cancer chemoprevention//Wei. Sheng. Yan. Jiu. 2003. V. 32. P. 159-162.</mixed-citation><mixed-citation xml:lang="en">Dai G., Wang X. Development of bladder cancer chemoprevention//Wei. Sheng. Yan. Jiu. 2003. V. 32. P. 159-162.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Mungan N.A., Vriesema J.L., Thomas C.M. et al. Urinary bladder cancer test: a new urinary tumor marker in the follow-up of superficial bladder cancer//Urology. 2000. P. 787-792.</mixed-citation><mixed-citation xml:lang="en">Mungan N.A., Vriesema J.L., Thomas C.M. et al. Urinary bladder cancer test: a new urinary tumor marker in the follow-up of superficial bladder cancer//Urology. 2000. P. 787-792.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Sanchez-Carbayo M., Herrero E., Megı.as J. et al. Comparative sensitivity of urinary CYFRA 21-1, UBC, TPA and NMP22 in the detection of bladder cancer//J. Urol. 1999. № 162. P. 1951-1956.</mixed-citation><mixed-citation xml:lang="en">Sanchez-Carbayo M., Herrero E., Megı.as J. et al. Comparative sensitivity of urinary CYFRA 21-1, UBC, TPA and NMP22 in the detection of bladder cancer//J. Urol. 1999. № 162. P. 1951-1956.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Yamashita S., Hoshi S., Ohyama C. et al. Urethral reccurence following neobladder in bladder cancer patients//Tohoku J. Exp. Med. 2003. V. 199. P. 197-203.</mixed-citation><mixed-citation xml:lang="en">Yamashita S., Hoshi S., Ohyama C. et al. Urethral reccurence following neobladder in bladder cancer patients//Tohoku J. Exp. Med. 2003. V. 199. P. 197-203.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
