<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2009-2-118-122</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-1801</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОТ НАУКИ К ПРАКТИКЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>FROM SCIENCE TO PRACTICE</subject></subj-group></article-categories><title-group><article-title>Фармакологическая коррекция феномена no-reflow при инфаркте миокарда</article-title><trans-title-group xml:lang="en"><trans-title>Pharmacological correction of no-reflow phenomenon in myocardial infarction treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мамонова</surname><given-names>Т. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Mamonova</surname><given-names>T. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мамонова Татьяна Юрьевна, научный сотрудник лаборатории клинической физиологии и фармакологии </p><p>тел +7-913-824-1662, факс (382-2) 41-88-93</p></bio><email xlink:type="simple">tm251@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Марков</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Markov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д р мед наук профессор руководитель отделения неотложной кардиологии</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Удут</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Udut</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д р мед наук профессор руководитель лаборатории клинической физиологии и фармакологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>НИИ фармакологии СО РАМН</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>НИИ кардиологии СО РАМН</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2009</year></pub-date><volume>8</volume><issue>2</issue><fpage>118</fpage><lpage>122</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мамонова Т.Ю., Марков В.А., Удут В.В., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Мамонова Т.Ю., Марков В.А., Удут В.В.</copyright-holder><copyright-holder xml:lang="en">Mamonova T.Y., Markov V.A., Udut V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/1801">https://bulletin.ssmu.ru/jour/article/view/1801</self-uri><abstract/><trans-abstract xml:lang="en"><p>This article presents the research findings on the impact of carvedilol on the course of the necrosis myocardium focus and malone dialdegid concentration with patients, afflicted with acute myocardial infarction. The study proves that carvedilol slows down the necrosis focus formation and relieves the intensity of the no-reflow phenomenon as well as the oxydative stress, in case it is administered prior to the trombolytic therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>инфаркт миокарда</kwd><kwd>карведилол</kwd><kwd>феномен no-reflow</kwd></kwd-group><kwd-group xml:lang="en"><kwd>myocardial infarction</kwd><kwd>carvedilol</kwd><kwd>no-reflow phenomenon</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бобров В.А., Симорот В.Н. Реперфузионные аритмии: механизмы развития, пути коррекции//Тер. архив. 1993. Т. 65. № 9. С. 56-62.</mixed-citation><mixed-citation xml:lang="en">Бобров В.А., Симорот В.Н. Реперфузионные аритмии: механизмы развития, пути коррекции//Тер. архив. 1993. Т. 65. № 9. С. 56-62.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Боровиков В.П., Боровиков И.П. Статистический анализ и обработка данных в среде Windows. М.: Филинъ, 1997. 608 с.</mixed-citation><mixed-citation xml:lang="en">Боровиков В.П., Боровиков И.П. Статистический анализ и обработка данных в среде Windows. М.: Филинъ, 1997. 608 с.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Гланц С. Медико-биологическая статистика: Пер. с англ./Под ред. Н.Е. Бузикашвили, Д.В. Самойлова. М.: Практика, 1999. 459 с.</mixed-citation><mixed-citation xml:lang="en">Гланц С. Медико-биологическая статистика: Пер. с англ./Под ред. Н.Е. Бузикашвили, Д.В. Самойлова. М.: Практика, 1999. 459 с.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Пархоменко А.Н. Феномен невосстановленного кровотока у больных с острым коронарным синдромом и возможные пути улучшения тканевой перфузии//Укр. кард. журнал. 2007. № 5. Режим доступа: http://www. rql.kiev.ua/cardio_j/2007/5/parkhomenko, свободный, http://www.rql.kiev.ua/cardio_j/fr_i_all.htm, свободный.</mixed-citation><mixed-citation xml:lang="en">Пархоменко А.Н. Феномен невосстановленного кровотока у больных с острым коронарным синдромом и возможные пути улучшения тканевой перфузии//Укр. кард. журнал. 2007. № 5. Режим доступа: http://www. rql.kiev.ua/cardio_j/2007/5/parkhomenko, свободный, http://www.rql.kiev.ua/cardio_j/fr_i_all.htm, свободный.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Galiutano L., Lombardo A., Maseri A. et al. Temporal evolution and functional outcome of no reflow: sustained and spontaneously reversible patterns following successful coronary recanalisation//Heart. 2003. V. 89. P. 731-737.</mixed-citation><mixed-citation xml:lang="en">Galiutano L., Lombardo A., Maseri A. et al. Temporal evolution and functional outcome of no reflow: sustained and spontaneously reversible patterns following successful coronary recanalisation//Heart. 2003. V. 89. P. 731-737.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Gressin V., Louvard Y., Pezzano M. et al. Holter recording of ventricular arrhythmias during intravenous thrombolysis for acute myocardial infarction//Am. J. Cardiology. 1992. V. 69. № 3. P. 152-159.</mixed-citation><mixed-citation xml:lang="en">Gressin V., Louvard Y., Pezzano M. et al. Holter recording of ventricular arrhythmias during intravenous thrombolysis for acute myocardial infarction//Am. J. Cardiology. 1992. V. 69. № 3. P. 152-159.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Sadanahan S., Hochman J.S. Early reperfusion, late reperfusion, and open artery hypothesis: an overview//Progress in Cardiovascular Diseases. 2000. V. 42. № 6. P. 397-404.</mixed-citation><mixed-citation xml:lang="en">Sadanahan S., Hochman J.S. Early reperfusion, late reperfusion, and open artery hypothesis: an overview//Progress in Cardiovascular Diseases. 2000. V. 42. № 6. P. 397-404.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Wagner G.S., Freye C.J., Palmeri S.T. et al. Evaluation of a QRS scoring system for estimating myocardial infarct size. I. Specificity and observer agreement//Circulation. 1982. V. 65. P. 342-347.</mixed-citation><mixed-citation xml:lang="en">Wagner G.S., Freye C.J., Palmeri S.T. et al. Evaluation of a QRS scoring system for estimating myocardial infarct size. I. Specificity and observer agreement//Circulation. 1982. V. 65. P. 342-347.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
