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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2009-3-32-36</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-1819</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКСПЕРИМЕНТАЛЬНЫЕ И КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERIMENTAL AND CLINICAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Цитокины «кожного окна» при атопическом дерматите</article-title><trans-title-group xml:lang="en"><trans-title>«Skin window» cytokines in atopic dermatitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Загрешенко</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Zagreshenko</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Загрешенко Денис Сергеевич, аспирант кафедры иммунологии и аллергологии </p><p>8-923-418-38-58</p></bio><email xlink:type="simple">zagreshenko@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Климов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Klimov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д р мед наук профессор зав кафедрой иммунологии и аллергологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Денисов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Denisov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд мед наук доцент кафедры иммунологии и аллергологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Саликова</surname><given-names>Т. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Salikova</surname><given-names>T. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант кафедры иммунологии и аллергологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фирсова</surname><given-names>Е. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Firsova</surname><given-names>Ye. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант кафедры иммунологии и аллергологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Сибирский государственный медицинский университет</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2009</year></pub-date><volume>8</volume><issue>3</issue><fpage>32</fpage><lpage>36</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Загрешенко Д.С., Климов В.В., Денисов А.А., Саликова Т.И., Фирсова Е.К., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Загрешенко Д.С., Климов В.В., Денисов А.А., Саликова Т.И., Фирсова Е.К.</copyright-holder><copyright-holder xml:lang="en">Zagreshenko D.S., Klimov V.V., Denisov A.A., Salikova T.I., Firsova Y.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/1819">https://bulletin.ssmu.ru/jour/article/view/1819</self-uri><abstract/><trans-abstract xml:lang="en"><p>There have been defined IL-4, IL-10, IL-17 and IFN-γ in cell-free skin exudate in 90 patients of atopic dermatitis depending on spread of dermal pathological process. There been found that variations of each cytokine had different features and reflected different parts of immunopathogenesis of the disease both in an acute period and remission and after allergenspecific immunotherapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>атопический дерматит</kwd><kwd>цитокины</kwd><kwd>"кожное окно"</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atopic dermatitis</kwd><kwd>cytokines</kwd><kwd>«skin window»</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бурместер Г.-Р., Пецутто А. Наглядная иммунология. М.: БИНОМ. Лаборатория знаний, 2007. 320 с.</mixed-citation><mixed-citation xml:lang="en">Бурместер Г.-Р., Пецутто А. Наглядная иммунология. М.: БИНОМ. Лаборатория знаний, 2007. 320 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Гланц С. 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