ssmuБюллетень сибирской медициныBulletin of Siberian Medicine1682-03631819-3684Siberian State Medical University, the Ministry of Healthcare of the Russian Federation10.20538/1682-0363-2019-1-76-83ssmu-2172Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEW AND LECTURESАллерген-ассоциированные молекулярные паттерны: новое слово в современной аллергологииAllergen-associated molecular patterns: a new trend in modern allergologyhttps://orcid.org/0000-0001-7594-6800СвиридоваВ. С.SviridovaV. S.

Свиридова Валентина Сергеевна, кандидат медицинских наук, ассистент, кафедра иммунологии и аллергологии

634050, г. Томск, Московский тракт, 2

Sviridova Valentina S., PhD, Assistant, Immunology and Allergology Department

Moscow Trakt, Tomsk, 634050

VSSviridova@mail.ruhttps://orcid.org/0000-0001-9831-4814ИсаевП. Ю.IsaevP. Yu.

Исаев Павел Юрьевич, ассистент, кафедра иммунологии и аллергологии

634050, г. Томск, Московский тракт, 2

Isaev Pavel Yu., Assistant, Immunology and Allergology Department

Moscow Trakt, Tomsk, 634050

https://orcid.org/0000-0001-6673-7556КлимовВ. В.KlimovV. V.

Климов Владимир Васильевич, доктор медицинских наук, профессор, заведующий кафедрой иммунологии и аллергологии

634050, г. Томск, Московский тракт, 2

Klimov Vladimir V., DM, Professor, Head of Immunology and Allergology Department

Moscow Trakt, Tomsk, 634050

https://orcid.org/0000-0003-1314-2625РомановаМ. И.RomanovaM. I.

Романова Мария Ивановна, ординатор, кафедра иммунологии и аллергологии

634050, г. Томск, Московский тракт, 2

Romanova Maria I., Physician, Immunology and Allergology Department

Moscow Trakt, Tomsk, 634050

https://orcid.org/0000-0002-6032-2402КошкароваН. С.KoshkarovaN. S.

Кошкарова Наталья Сергеевна, кандидат медицинских наук, ассистент, кафедра иммунологии и аллергологии

634050, г. Томск, Московский тракт, 2

Koshkarova Natalia S., PhD, Assistant, Immunology and Allergology Department

Moscow Trakt, Tomsk, 634050

Сибирский государственный медицинский университет (СибГМУ)РоссияSiberian State Medical University (SSMU)Russian Federation2019160520191817683Copyright © Свиридова В.С., Исаев П.Ю., Климов В.В., Романова М.И., Кошкарова Н.С., 20192019Свиридова В.С., Исаев П.Ю., Климов В.В., Романова М.И., Кошкарова Н.С.Sviridova V.S., Isaev P.Y., Klimov V.V., Romanova M.I., Koshkarova N.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://bulletin.ssmu.ru/jour/article/view/2172

В последнее десятилетие ни у кого не вызывает сомнения факт важности вовлечения в формирование адаптивного иммунного ответа компонентов врожденной иммунной системы. Основным триггером, вызывающим активацию врожденного иммунитета, являются молекулярные паттерны. В статье рассмотрены вопросы, касающиеся роли паттернов в механизмах иммунитета, а также освещены новые данные об аллерген-ассоциированных молекулярных паттернах.

Over the last decade the role of innate immunity has been known to be crucial for the activation of adaptive immune system. The main triggers that upregulate reactions of innate immunity are small exogenous molecules with conserved motifs, molecular patterns. The article discusses a variety of possible roles of molecular patterns in the immune mechanisms, including the participation of Allergen Associated Molecular Patterns (AAMPs) in allergic processes.

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The authors declare that there are no conflicts of interest present.