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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2019-1-96-108</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-2174</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Оценка индикаторов медико-биологического мониторинга йододефицитных заболеваний</article-title><trans-title-group xml:lang="en"><trans-title>Assessment of indicators of medical and biological monitoring of iodine deficiency diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9253-8075</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суплотова</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Suplotova</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Суплотова Людмила Александровна, доктор медицинских наук, профессор, заведующая курсом ýндокринологии кафедры терапии, Тюменский ГМУ, главный ýндокринолог Тюменской области</p><p>625023, г. Тюмень, ул. Одесская, 54 </p></bio><bio xml:lang="en"><p>Suplotova Ludmila А., DM, Рrofessor, Нead of the Тhеrapy Department, Tyumen State Medical University, Head endocrinologist of the Tyumen region</p><p>54, Odesskaya Str., Tyumen, 625023</p></bio><email xlink:type="simple">suplotovala@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4663-0289</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макарова</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarova</surname><given-names>O. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Макарова Ольга Борисовна, кандидат медицинских наук, доцент, кафедра терапии</p><p>625023, г. Тюмень, ул. Одесская, 54 </p></bio><bio xml:lang="en"><p>Makarova Olga В., PhD, Аssistant Рrofessor, Тhеrapy Department</p><p>54, Odesskaya Str., Tyumen, 625023</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1650-1243</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ковальжина</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovalzhina</surname><given-names>L. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ковальжина Лариса Сергеевна, кандидат сельско-хозяйственных наук, доцент, кафедра менеджмента в отраслях</p><p>625000, г. Тюмень, ул. Володарского, 38 </p></bio><bio xml:lang="en"><p>Kovalzhina Larisa S., PhD, Аssistant Рrofessor, Management in the Sectors of Energy</p><p>38, Volodarskogo Str., Tyumen, 625000</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0772-8224</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шарухо</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sharuho</surname><given-names>G. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шарухо Галина Васильевна, доктор медицинских наук, руководитель Управления федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека по Тюменской области</p><p>625023, г. Тюмень, ул. Одесская, 54, </p><p>625026, г. Тюмень, ул. Рижская, 45А</p></bio><bio xml:lang="en"><p>Sharuho Galina V., DM, Head of the Federal Service for Supervision of Consumer Rights and Human Welfare in the Tyumen region</p><p>54, Odesskaya Str., Tyumen, 625023, </p><p>45А, Righskaya Str., Tyumen 625026</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тюменский государственный медицинский университет (ГМУ)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tyumen State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Тюменский индустриальный университет (ТИИ)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Industrial University of Tyumen</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Тюменский государственный медицинский университет (ГМУ);&#13;
Управление федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека по Тюменской области</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tyumen State Medical University;&#13;
Federal Service for Supervision of Consumer Rights and Human Welfare in the Tyumen Region</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>16</day><month>05</month><year>2019</year></pub-date><volume>18</volume><issue>1</issue><fpage>96</fpage><lpage>108</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Суплотова Л.А., Макарова О.Б., Ковальжина Л.С., Шарухо Г.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Суплотова Л.А., Макарова О.Б., Ковальжина Л.С., Шарухо Г.В.</copyright-holder><copyright-holder xml:lang="en">Suplotova L.A., Makarova O.B., Kovalzhina L.S., Sharuho G.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/2174">https://bulletin.ssmu.ru/jour/article/view/2174</self-uri><abstract><p>Проблема йодного дефицита остается актуальной во всем мире в связи с широкой распространенностью и негативным влиянием на здоровье человека во все возрастные периоды. Йодный дефицит приводит к снижению интеллектуального потенциала у детей, развитию репродуктивных нарушений в молодом возрасте, а также к формированию многоузлового токсического зоба как крайней точки зобной трансформации, сопровождающейся нарушениями сердечного ритма в среднем и пожилом возрасте. В обзоре освещаются вопросы мониторинга йодного дефицита в регионах, приводятся данные ситуации в мире на этапе становления программ профилактики и в настоящее время. Проведен детальный анализ каждого критерия тяжести йодного дефицита и эффективности профилактических программ. Особое внимание уделено критерию неонатальной гипертиреотропинемии как перспективного индикатора мониторинга йодного дефицита.</p></abstract><trans-abstract xml:lang="en"><p>The problem of iodine deficiency remains relevant all over the world due to the widespread prevalence and the negative impact it has on human health in all agegroups. Iodine deficiency leads to a decrease in the intellectual potential of children, the development of reproductive disorders at a young age, as well as the formation of multinodular toxic goiter as the last stage of goiter transformation, accompanied by heart rhythm disturbances in middle and old age. The article covers the issues of monitoring iodine deficiency in the regions of Russia and provides data on the situation in the world on the development of future prevention programs and current prevention programs. A detailed analysis of each criterion for the severity of iodine deficiency and the effectiveness of preventive programs was carried out. Particular attention is paid to the criterion of neonatal hyperthyrotropinemia as a promising indicator for monitoring iodine deficiency.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>йодный дефицит</kwd><kwd>медико-биологический мониторинг</kwd><kwd>индикаторы</kwd><kwd>неонатальная гипертиреотропинемия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>iodine deficiency</kwd><kwd>biomedical monitoring</kwd><kwd>indicators</kwd><kwd>neonatal hyperthyrotropinemia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Герасимов Г.А., Фадеев В.В., Свириденко Н.Ю., Мельниченко Г.А., Дедов И.И. Йоддефицитные заболевания в России. Простое решение сложной проблемы. М.: Адамантъ, 2002: 168.</mixed-citation><mixed-citation xml:lang="en">Gerasimov G.A., Fadeev V.V., Sviridenko N.Ju., Mel'nichenko G.A., Dedov I.I. Iodine deficiency disorders in Russia. 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