References

ssmu

Бюллетень сибирской медицины

Bulletin of Siberian Medicine

1682-03631819-3684

Siberian State Medical University, the Ministry of Healthcare of the Russian Federation

10.20538/1682-0363-2019-2-181-194

ssmu-2318

Research Article

ОБЗОРЫ И ЛЕКЦИИ

REVIEW AND LECTURES

Противоопухолевая активность флавоноидов

Antitumor activity of flavonoids

Зверев

Я. Ф.

Zverev

Y. F.

zver@agmu.ru

Алтайский государственный медицинский университет (АГМУ)РоссияAltai State Medical University (ASMU)Russian Federation

2019

11082019

182181194

2019

Зверев Я.Ф.

Zverev Y.F.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://bulletin.ssmu.ru/jour/article/view/2318

Обзор литературы посвящен рассмотрению механизмов противоопухолевого действия флавоноидов. Антиканцероматозный эффект флавоноидов обсуждается в контексте их воздействия на основные этапы развития злокачественных опухолевых клеток. При этом подробно рассматривается влияние флавоноидов на активность протеинкиназ, металлопротеиназ, апоптоза, ангиогенеза и клеточного цикла опухолевых клеток.

This review of the literature is devoted to the consideration of mechanisms of the antitumor effect of flavonoids. The anticanceromatous effect of flavonoids is discussed in the context of their impact on the main stages of development of malignant tumor cells. At the same time, the influence of flavonoids on the activity of protein kinases, metalloproteinases, apoptosis, angiogenesis and the cell cycle of tumor cells is considered in detail.

флавоноидымеханизмы противоопухолевого действия.

flavonoidsmechanisms of antitumor effect

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The authors declare that there are no conflicts of interest present.