<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2019-4-26-35</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-2552</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL PAPERS</subject></subj-group></article-categories><title-group><article-title>Распространенность нарушений сна среди пациентов с зависимостью от различных психоактивных веществ</article-title><trans-title-group xml:lang="en"><trans-title>The prevalence of the sleep disturbances among the patients with substance use disorders</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9698-0327</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ветрова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vetrova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>науч. сотрудник, лаборатории клинической фармакологии аддиктивных состояний,</p><p>192019, г. Санкт-Петербург, ул. Бехтерева, 3;</p><p>197022, г. Санкт-Петербург, ул. Л. Толстого, 6/8</p></bio><bio xml:lang="en"><p>Research Associate, Laboratory of Clinical Pharmacology of Addictions,</p><p>3, Bekhterev Str., Saint Petersburg, 192019;</p><p>6/8, L’va Tolstogo Str., Saint Petersburg, 197089</p></bio><email xlink:type="simple">mvetrova11@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8033-4833</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кучменко</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuchmenko</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>мл. науч. сотрудник, отделение лечения больных алкоголизмом,</p><p>192019, г. Санкт-Петербург, ул. Бехтерева, 3</p></bio><bio xml:lang="en"><p>Junior Researcher, Department of Addictions,</p><p>3, Bekhterev Str., Saint Petersburg, 192019</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2265-9108</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Генина</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Genina</surname><given-names>I. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач психиатр-нарколог, зав. отделением,</p><p>199004, г. Санкт-Петербург, 5-я линия В.О., 48</p></bio><bio xml:lang="en"><p>Addiction Psychiatrist, Head of the Department,</p><p>48, 5th line of Vasilyevsky Island, Saint Petersburg, 199004</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2110-5525</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гончаров</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Goncharov</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, ст. науч. сотрудник, отделение лечения больных алкоголизмом,</p><p>192019, г. Санкт-Петербург, ул. Бехтерева, 3</p></bio><bio xml:lang="en"><p>PhD, Senior Researcher, Department of Addictions,</p><p>3, Bekhterev Str., Saint Petersburg, 192019</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1797-1121</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рыбакова</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rybakova</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, вед. науч. сотрудник, отделение лечения больных алкоголизмом,</p><p>192019, г. Санкт-Петербург, ул. Бехтерева, 3</p></bio><bio xml:lang="en"><p>V., PhD, Leading Researcher, Department of Addictions, </p><p>3, Bekhterev Str., Saint Petersburg, 192019</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2798-8800</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, гл. науч. сотрудник, руководитель научно-организационного отделения,</p><p>192019, г. Санкт-Петербург, ул. Бехтерева, 3</p></bio><bio xml:lang="en"><p>DM, Senior Researcher, Chief of the Research Organization Department,</p><p>3, Bekhterev Str., Saint Petersburg, 192019</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8941-2460</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зубова</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zubova</surname><given-names>E. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, руководитель учебного центра,</p><p>192019, г. Санкт-Петербург, ул. Бехтерева, 3</p></bio><bio xml:lang="en"><p>DM, Chief of the Training Center,</p><p>3, Bekhterev Str., Saint Petersburg, 192019</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3145-1448</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киселев</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiselev</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>специалист по биомедицинской статистике,</p><p>192019, г. Санкт-Петербург, ул. Бехтерева, 3</p></bio><bio xml:lang="en"><p>Biostatistician,</p><p>3, Bekhterev Str., Saint Petersburg, 192019</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5618-4206</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Незнанов</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Neznanov</surname><given-names>N. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, профессор, директор,</p><p>192019, г. Санкт-Петербург, ул. Бехтерева, 3</p></bio><bio xml:lang="en"><p>DM, Professor, Director,</p><p>3, Bekhterev Str., Saint Petersburg, 192019</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0529-4525</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крупицкий</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Krupitsky</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф., руководитель отдела аддиктологии, зам. директора по научной части, 192019, г. Санкт-Петербург, ул. Бехтерева, 3;</p><p>зав. лабораторией клинической фармакологии аддиктивных состояний, 197022, г. Санкт-Петербург, ул. Л. Толстого, 6/8</p></bio><bio xml:lang="en"><p>DM, Professor, Deputy Director for Science and Head of the Department of Addictions, 3, Bekhterev Str., Saint Petersburg, 192019;</p><p>Chief of the Laboratory of Clinical Psychopharmacology of Addictions, 6/8, L’va Tolstogo Str., Saint Petersburg, 197089</p></bio><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр психиатрии и неврологии&#13;
(НМИЦ ПН) имени В.М. Бехтерева;&#13;
Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова (ПСПбГМУ им. И.П. Павлова)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.M. Bekhterev National Medical Research Center of Psychiatry and Neurology;&#13;
I.P. Pavlov First Saint Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр психиатрии и неврологии&#13;
(НМИЦ ПН) имени В.М. Бехтерева</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.M. Bekhterev National Medical Research Center of Psychiatry and Neurology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Городская наркологическая больница</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Addiction Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр психиатрии и неврологии (НМИЦ ПН) имени В.М. Бехтерева</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.M. Bekhterev National Medical Research Center of Psychiatry and Neurology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр психиатрии и неврологии (НМИЦ ПН) имени В.М. Бехтерева;&#13;
Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова (ПСПбГМУ им. И.П. Павлова)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.M. Bekhterev National Medical Research Center of Psychiatry and Neurology;&#13;
I.P. Pavlov First Saint Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>14</day><month>01</month><year>2020</year></pub-date><volume>18</volume><issue>4</issue><fpage>26</fpage><lpage>35</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ветрова М.В., Кучменко Д.Н., Генина И.Н., Гончаров О.В., Рыбакова К.В., Семенова Н.В., Зубова Е.Ю., Киселев А.С., Незнанов Н.Г., Крупицкий Е.М., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Ветрова М.В., Кучменко Д.Н., Генина И.Н., Гончаров О.В., Рыбакова К.В., Семенова Н.В., Зубова Е.Ю., Киселев А.С., Незнанов Н.Г., Крупицкий Е.М.</copyright-holder><copyright-holder xml:lang="en">Vetrova M.V., Kuchmenko D.N., Genina I.N., Goncharov O.V., Rybakova K.V., Semenova N.V., Zubova E.Y., Kiselev A.S., Neznanov N.G., Krupitsky E.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/2552">https://bulletin.ssmu.ru/jour/article/view/2552</self-uri><abstract><sec><title>Введение</title><p>Введение. Расстройства сна могут приводить к развитию заболеваний, связанных с употреблением психоактивных веществ (ПАВ). В настоящее время сравнительно мало известно о распространенности нарушений сна у лиц с наркологическими заболеваниями в России.</p></sec><sec><title>Цель</title><p>Цель. Определение частоты встречаемости расстройств сна у пациентов (n = 196) с синдромом зависимости от алкоголя (АЗ, n = 102), от опиоидов (ОЗ, n = 55) и полисубстантной зависимостью (ПЗ, n = 39), обращавшихся за наркологической помощью.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведено кросс-секционное исследование нарушений сна больных в г. Санкт-Петербурге в период с 2017 по 2018 г. Оценка нарушений сна проводилась с использованием модифицированного опросника «Индекс тяжести инсомнии». Наличие расстройств сна оценивалось в разные временные периоды: когда-либо в жизни, за последние 12 мес и за последние 30 сут.</p></sec><sec><title>Результаты</title><p>Результаты. Во всех исследуемых группах у значительного количества больных (49,0–76,5% из 196) отмечались определенные расстройства сна. В частности, различные инсомнические расстройства за последние 30 сут наиболее часто встречались в группе АЗ (60,8–73,5% из 102), причем наиболее актуальной жалобой было раннее пробуждение. В группе ПЗ наиболее часто встречались расстройства сна в течение жизни (94,9–100,0% из 39), тогда как за последние 30 сут инсомнические расстройства были относительно редки. Однако именно нарушения сна за последние 30 сут статистически значимо чаще (p &lt; 0,05) отмечались в группе пациентов, активно потребляющих наркотические вещества (40,2–87,2%), по сравнению с группой пациентов в ремиссии (0–16,7%).</p></sec><sec><title>Заключение</title><p>Заключение. Полученные результаты демонстрируют высокую распространенность инсомнических расстройств среди пациентов с зависимостью от ПАВ. Результаты исследования свидетельствуют о положительном влиянии ремиссии на сон и указывают на необходимость дальнейшего изучения влияния нарушений сна на течение аддиктивного заболевания.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. There is evidence that sleep disorders may be significantly linked to the development of the substance use disorders (SUD). However, data about the prevalence of the sleep disturbances among patients with SUD in Russia are relatively limited.</p></sec><sec><title>Aim</title><p>Aim. To evaluate the frequency of the sleep disturbances among patients (n = 196) with alcohol (ÀD, n = 102), opioid (ÎD, n = 55) and polysubstance dependence (PD, n = 39) seeking addiction medical care.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. We conduct a cross-sectional study of sleep disturbances among patients in St. Petersburg in 2017–2018. The modified Insomnia Severity Index (ISI) was administered to assess sleep during different periods of time: lifetime, the past 12 months, and the past 30 days.</p></sec><sec><title>Results</title><p>Results. All groups demonstrated relatively high presence of different sleep disorders (range: 49.0–76.5% among 196). The sleep disturbances over the past 30 days were more common in the AD group (60.8– 73.5% among 102) with the early morning awakening as the most frequent complaint. In the PD group the prevalence of lifetime sleep disturbances was high (94.9–100.0% among 39), whereas insomnia disorders were relatively rare over the past 30 days. However, it was sleep disturbances over the past 30 days that were statistically significantly more often (p &lt; 0,05) observed in the group of patients who actively consume narcotic substances (40.2–87.2%), compared with the group of patients in remission (0–16.7%).</p></sec><sec><title>Conclusion</title><p>Conclusion. The results demonstrated the high prevalence of insomnia among patients with SUD and suggested that the remission have a positive effect on the symptoms of sleep disorders. Further studies of the association between sleep disturbances and SUD progression are needed. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>нарушения сна</kwd><kwd>наркологическое заболевание</kwd><kwd>алкоголь</kwd><kwd>опиоиды</kwd><kwd>полисубстантная зависимостьнарушения сна</kwd><kwd>наркологическое заболевание</kwd><kwd>алкоголь</kwd><kwd>опиоиды</kwd><kwd>полисубстантная зависимость</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sleep disorders</kwd><kwd>chronobiological rhythms</kwd><kwd>substance use disorders</kwd><kwd>alcohol</kwd><kwd>opioids</kwd><kwd>psychostimulants</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Smith N., Hill R., Marshall J., Keaney F., Wanigaratne S. Sleep related beliefs and their association with alcohol relapse following residential alcohol detoxification treatment. Behav. Cogn. Psychother. 2014; 42 (5): 593–604. DOI: 10.1017/S1352465813000465.</mixed-citation><mixed-citation xml:lang="en">Smith N., Hill R., Marshall J., Keaney F., Wanigaratne S. Sleep related beliefs and their association with alcohol relapse following residential alcohol detoxification treatment. Behav. Cogn. Psychother. 2014; 42 (5): 593–604. DOI: 10.1017/S1352465813000465.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Angarita G.A., Emadi N., Hodges S., Morgan P.T. Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review. Addict. Sci. Clin. Pract. 2016; 11 (1): 9. DOI: 10.1186/ s13722-016-0056-7.</mixed-citation><mixed-citation xml:lang="en">Angarita G.A., Emadi N., Hodges S., Morgan P.T. Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review. Addict. Sci. Clin. Pract. 2016; 11 (1): 9. DOI: 10.1186/ s13722-016-0056-7.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Roehrs T.A., Roth T. Sleep disturbance in substance use disorders. Psychiatr. Clin. North Am. 2015; 38 (4): 793–803. DOI: 10.1016/j.psc.2015.07.008.</mixed-citation><mixed-citation xml:lang="en">Roehrs T.A., Roth T. Sleep disturbance in substance use disorders. Psychiatr. Clin. North Am. 2015; 38 (4): 793–803. DOI: 10.1016/j.psc.2015.07.008.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Sorscher A.J., Siddiqui A.A., Olson A., Johnson D. Pharmacotherapy for сhronic insomnia: A brief survey of PCP attitudes and preferences. J. Sleep Disor: Treat Care. 2016; 5: 1. DOI: 10.4172/2325-9639.1000169.</mixed-citation><mixed-citation xml:lang="en">Sorscher A.J., Siddiqui A.A., Olson A., Johnson D. Pharmacotherapy for сhronic insomnia: A brief survey of PCP attitudes and preferences. J. Sleep Disor: Treat Care. 2016; 5: 1. DOI: 10.4172/2325-9639.1000169.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Полуэктов М.Г., Левин Я.И. Расстройства сна и их лечение. Журнал неврологии и психиатрии им. C.C. Корсакова. 2010; 110 (9): 70–75.</mixed-citation><mixed-citation xml:lang="en">Poluehktov M.G., Levin Yа.I. Sleep disorders and their treatment. S.S. Korsakov Journal of Neurology and Psychiatry. 2010; 110 (9): 70–75. (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Brower K.J. Insomnia, alcoholism and relapse. Sleep Med. Rev. 2003; 7 (6): 523–539. DOI: 10.1016/S1087-0792(03)90005-0.</mixed-citation><mixed-citation xml:lang="en">Brower K.J. Insomnia, alcoholism and relapse. Sleep Med. Rev. 2003; 7 (6): 523–539. DOI: 10.1016/S1087-0792(03)90005-0.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Miller M.B., Donahue M.L., Carey K.B., Scott-Sheldon L.A. Insomnia treatment in the context of alcohol use disorder: a systematic review and meta-analysis. Drug. Alcohol. Depend. 2017; 181: 200–207. DOI: 10.1016/j.drugalcdep.2017.09.029.</mixed-citation><mixed-citation xml:lang="en">Miller M.B., Donahue M.L., Carey K.B., Scott-Sheldon L.A. Insomnia treatment in the context of alcohol use disorder: a systematic review and meta-analysis. Drug. Alcohol. Depend. 2017; 181: 200–207. DOI: 10.1016/j.drugalcdep.2017.09.029.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Morin C.M., Belleville G., Bйlanger L., Ivers H. The Insomnia Severity Index: Psychometric Indicators to Detect Insomnia Cases and Evaluate Treatment Response. Sleep. 2011; 34 (5): 601–608. DOI: 10.1093/sleep/34.5.601.</mixed-citation><mixed-citation xml:lang="en">Morin C.M., Belleville G., Bйlanger L., Ivers H. The Insomnia Severity Index: Psychometric Indicators to Detect Insomnia Cases and Evaluate Treatment Response. Sleep. 2011; 34 (5): 601–608. DOI: 10.1093/sleep/34.5.601.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Cohn T., Foster J., Peters T. Sequential studies of sleep disturbance and quality of life in abstaining alcoholics. Addict. Biol. 2003; 8 (4): 455–462. DOI: 10.1080/13556210310001646439.</mixed-citation><mixed-citation xml:lang="en">Cohn T., Foster J., Peters T. Sequential studies of sleep disturbance and quality of life in abstaining alcoholics. Addict. Biol. 2003; 8 (4): 455–462. DOI: 10.1080/13556210310001646439.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Голенков А.В., Полуэктов М.Г. Распространенность нарушений сна у жителей Чувашии (данные сплошного анкетного опроса). Журнал неврологии и психиатрии им. С.С. Корсакова. 2011; 111 (6): 64–67.</mixed-citation><mixed-citation xml:lang="en">Golenkov A.V., Poluektov M.G. The prevalence of sleep disorders among residents of Chuvashia (data from a continuous questionnaire survey). S.S. Korsakov Journal of Neurology and Psychiatry. 2011; 111 (6): 64–67 (in Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Brower K.J., Krentzman A., Robinson E.A.R. Persistent insomnia, abstinence, and moderate drinking in alcohol-dependent individuals. Am. J. Addict. 2011; 20 (5): 435–440. DOI: 10.1111/j.1521-0391.2011.00152.x.</mixed-citation><mixed-citation xml:lang="en">Brower K.J., Krentzman A., Robinson E.A.R. Persistent insomnia, abstinence, and moderate drinking in alcohol-dependent individuals. Am. J. Addict. 2011; 20 (5): 435–440. DOI: 10.1111/j.1521-0391.2011.00152.x.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Brower K.J. Assessing and treating insomnia related to alcohol use disorders. Curr. Addict. Rep. 2016; 3 (1): 98–108. DOI: 10.1007/s40429-016-0083-1.</mixed-citation><mixed-citation xml:lang="en">Brower K.J. Assessing and treating insomnia related to alcohol use disorders. Curr. Addict. Rep. 2016; 3 (1): 98–108. DOI: 10.1007/s40429-016-0083-1.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Brower K.J., Perron B.E. Sleep disturbance as a universal risk factor for relapse in addictions to psychoactive substances. Med. Hypotheses. Elsevier Ltd. 2010; 74 (5): 928–933. DOI: 10.1016/j.mehy.2009.10.020.</mixed-citation><mixed-citation xml:lang="en">Brower K.J., Perron B.E. Sleep disturbance as a universal risk factor for relapse in addictions to psychoactive substances. Med. Hypotheses. Elsevier Ltd. 2010; 74 (5): 928–933. DOI: 10.1016/j.mehy.2009.10.020.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Dolsen M.R., Harvey A.G. Life-time history of insomnia and hypersomnia symptoms as correlates of alcohol, cocaine and heroin use and relapse among adults seeking substance use treatment in the United States from 1991 to 1994. Addiction. 2017; 112 (6): 1104–1111. DOI: 10.1111/add.13772.</mixed-citation><mixed-citation xml:lang="en">Dolsen M.R., Harvey A.G. Life-time history of insomnia and hypersomnia symptoms as correlates of alcohol, cocaine and heroin use and relapse among adults seeking substance use treatment in the United States from 1991 to 1994. Addiction. 2017; 112 (6): 1104–1111. DOI: 10.1111/add.13772.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
