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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2007-1-83-87</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-3225</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group></article-categories><title-group><article-title>Т-лимфоциты - ключевые иммунорегуляторные клетки</article-title><trans-title-group xml:lang="en"><trans-title>Т lymphocytes are key immune regulating cells</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Свиридова</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sviridova</surname><given-names>V. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кологривова</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Коlogrivova</surname><given-names>Ye. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пронина</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pronina</surname><given-names>N. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Елисеева</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yeliseyeva</surname><given-names>L. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Читалкина</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chitalkina</surname><given-names>A. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Сибирский государственный медицинский университет</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Томская областная клиническая больница</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2007</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2007</year></pub-date><volume>6</volume><issue>1</issue><fpage>83</fpage><lpage>87</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Свиридова В.С., Кологривова Е.Н., Пронина Н.А., Елисеева Л.В., Читалкина А.А., 2007</copyright-statement><copyright-year>2007</copyright-year><copyright-holder xml:lang="ru">Свиридова В.С., Кологривова Е.Н., Пронина Н.А., Елисеева Л.В., Читалкина А.А.</copyright-holder><copyright-holder xml:lang="en">Sviridova V.S., Коlogrivova Y.N., Pronina N.A., Yeliseyeva L.V., Chitalkina A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/3225">https://bulletin.ssmu.ru/jour/article/view/3225</self-uri><abstract><p>Обсуждается фенотипическая и функциональная гетерогенность иммунорегуляторных субпопуляций Т-лимфоцитов с супрессорной активностью. Наиболее подробно охарактеризованы натуральные регуляторные и индуцибельные регуляторные клетки.</p></abstract><trans-abstract xml:lang="en"><p>Phenotypical and functional heterogeneity of immune regulating subpopulations of T-lymphocytes having suppressor activity is discussed in the article. Natural regulators and inducible regulating cells are characterized in more details.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Т-хелперы</kwd><kwd>Т-регуляторы</kwd><kwd>натуральные регуляторные клетки</kwd><kwd>индуцибельные регуляторные клет-ки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>T-helpers</kwd><kwd>T-regulators</kwd><kwd>natural regulating cells</kwd><kwd>inducible regulating cells</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Aihara M., Dobashi K., Iizuka K. et al. 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