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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2008-2-70-78</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-3380</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group></article-categories><title-group><article-title>Использование магнитных наночастиц в биомедицине</article-title><trans-title-group xml:lang="en"><trans-title>Application of magnetic nanoparticles in biomedicine</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Першина</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Pershina</surname><given-names>A. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сазонов</surname><given-names>Алексей Эдуардович</given-names></name><name name-style="western" xml:lang="en"><surname>Sazonov</surname><given-names>A. E.</given-names></name></name-alternatives><email xlink:type="simple">liotech@ssmu.net.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мильто</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Milto</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Сибирский государственный медицинский университет</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2008</year></pub-date><volume>7</volume><issue>2</issue><fpage>70</fpage><lpage>78</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Першина А.Г., Сазонов А.Э., Мильто И.В., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Першина А.Г., Сазонов А.Э., Мильто И.В.</copyright-holder><copyright-holder xml:lang="en">Pershina A.G., Sazonov A.E., Milto I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/3380">https://bulletin.ssmu.ru/jour/article/view/3380</self-uri><abstract><p>Применение наноматералов открывает широкие перспективы благодаря появлению у вещества в наноразмерном состоянии уникальных свойств. В настоящее время на основе наночастиц разрабатывают высокoспецифичные диагностические системы и эффектив ные методы терапии. В обзоре рассмотрены основные направления биомедицинского применения магнитных наночастиц: магнитная сепарация, биосенсоры, контрастирование при MRI-диагностике, управляемая локальная гипертермия опухолей, целевая доставка препаратов, генотерапия, а также конструирование тканей.</p></abstract><trans-abstract xml:lang="en"><p>The use of nanomaterials offers many advantages due to their unique properties. They can be used as building blocks for the fabrication of various functional diagnostic systems and agents of therapy. This article focuses on the application of magnetic nanoparticles in biomedicine such as magnetic separation, biosensor, contrast agents for MRI (magnetic resonance imaging), local operated hyperthermic treatment of tumors, drug delivery, gene therapy, tissue engineering.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>магнитные наночастицы</kwd><kwd>биомедицина</kwd><kwd>magnetic nanoparticles</kwd><kwd>biomedicine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Губин С.П., Кокшаров Ю.А., Хомутов Г.Б. и др. // Успехи химии. 2005. № 74. В. 6. С. 539.</mixed-citation><mixed-citation xml:lang="en">Губин С.П., Кокшаров Ю.А., Хомутов Г.Б. и др. // Успехи химии. 2005. № 74. В. 6. С. 539.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Гусев А.И., Ремпель А.А. Нанокристаллические материалы. 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