<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2014-2-88-94</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-35</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГУМАНИТАРНЫЕ ПРОБЛЕМЫ БИОЛОГИИ И МЕДИЦИНЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HUMANITARIAN PROBLEMS OF BIOLOGY AND MEDICINE</subject></subj-group></article-categories><title-group><article-title>ОКРУЖНОСТЬ ТАЛИИ КАК ИНДИКАТОР КОМПОНЕНТОВ МЕТАБОЛИЧЕСКОГО СИНДРОМА В СИБИРСКОЙ ПОПУЛЯЦИИ</article-title><trans-title-group xml:lang="en"><trans-title>WAIST CIRCUMFERENCE AS INDICATOR COMPONENTS OF METABOLIC SYNDROME IN THE SIBERIAN POPULATION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Симонова</surname><given-names>Г. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Simonova</surname><given-names>G. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Симонова Галина Ильинична, заслуженный деятель науки РФ, доктор медицинских наук, профессор, Лаборатория клинико-популяционных и профилактических исследований терапевтических и эндокринных заболеваний и лаборатория этиопатогенеза и клиники внутренних заболеваний</p></bio><bio xml:lang="en"/><email xlink:type="simple">svetlana3548@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мустафина</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mustafina</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мустафина Светлана Владимировна, кандидат медицинских наук, Лаборатория клиникопопуляционных и профилактических исследований терапевтических и эндокринных заболеваний и лаборатория этиопатогенеза и клиники внутренних заболеваний</p></bio><bio xml:lang="en"/><email xlink:type="simple">svetlana3548@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитин</surname><given-names>Ю. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitin</surname><given-names>Yu. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никитин Юрий Петрович, академик РАМН, профессор, Лаборатория клиникопопуляционных и профилактических исследований терапевтических и эндокринных заболеваний и лаборатория этиопатогенеза и клиники внутренних заболеваний</p></bio><bio xml:lang="en"/><email xlink:type="simple">svetlana3548@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щербакова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shcherbakova</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Щербакова Лилия Валерьевна, старший научный сотрудник, Лаборатория клинико-популяционных и профилактических исследований терапевтических и эндокринных заболеваний и лаборатория этиопатогенеза и клиники внутренних заболеваний</p></bio><bio xml:lang="en"/><email xlink:type="simple">svetlana3548@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт терапии и профилактической медицины Сибирского отделения РАМН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Internal Medicine SB RAMS, Novosibirsk</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2014</year></pub-date><volume>13</volume><issue>2</issue><fpage>88</fpage><lpage>94</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Симонова Г.И., Мустафина С.В., Никитин Ю.П., Щербакова Л.В., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Симонова Г.И., Мустафина С.В., Никитин Ю.П., Щербакова Л.В.</copyright-holder><copyright-holder xml:lang="en">Simonova G.I., Mustafina S.V., Nikitin Y.P., Shcherbakova L.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/35">https://bulletin.ssmu.ru/jour/article/view/35</self-uri><abstract><p>Цель исследования – определить наиболее информативное значение окружности талии (ОТ) для идентификации компонентов метаболического синдрома и сахарного диабета по данным эпидемиологического исследования в крупном промышленном центре Западной Сибири.В период с 2003 по 2005 г. в рамках популяционного скрининга обследовано 9362 человека, в том числе 4268 мужчин (45,6%) и 5094 женщин (54,4%). Отклик составил 61% от расчетного числа приглашенных. Протокол исследования включал оценку социально-демографических данных, измерение артериального давления (АД), антропометрию (рост, вес, ОТ), определение биохимических показателей. Статистическая обработка полученных результатов проведена с помощью пакета SPSS (V. 13.0). Для определения отрезных точек ОТ использована ROC-модель.В подгруппе, имеющей более 2 компонентов метаболического синдрома (МС), отрезная точка ОТ у мужчин составила 93,3 см (чувствительность 72%, специфичность 83%), у женщин – 90,2 см (чувствительность 72%, специфичность 62%). При идентификации АД 130/85 мм рт. ст. отмечается наименьшее значение отрезной точки ОТ – 90 см (чувствительность 66,8%, специфичность 58,1%) у мужчин, 86,5 см (чувствительность 71,0%, специфичность 55,7%) у женщин. При идентификации лиц с сахарным диабетом (СД) определено наибольшее значение отрезной точки ОТ – 99,0 см (чувствительность 61,0%, специфичность 70,2%) у мужчин и 95,1 см (чувствительность 64,1%, специфичность 65,9%) у женщин.В сибирской популяции 45–69 лет для идентификации лиц с наличием более 2 компонентов МС пороговое значение ОТ составило 93,3 см для мужчин и 90,2 см для женщин. Из всех анализируемых компонентов МС наименьшее пороговое значение ОТ определено для распознавания АДболее 130/85 мм рт. ст. как у мужчин, так и у женщин, и составляет 90 см и 86,5 см соответственно. Отрезная точка ОТ для идентификации СД имеет наибольшее значение: 99,0 см у мужчин и 95,1 см у женщин.</p></abstract><trans-abstract xml:lang="en"><p>Object of research: to determine the cut-off point of waist circumference (WC) identify the components of metabolic syndrome (MS) in a large industrial center of Western Siberia.In the period from 2003 to 2005 in the screening population surveyed 9362 people, including 4268 men (45.6%) and 5094 women (54.4%).The response rate was 61%. The study protocol included a sociodemographic data, measurement of blood pressure (BP), anthropometry (height, weight, WC), the definition of biochemical parameters. Statistical analysis was performed using the package SPSS. To determine the cut-off points of the used ROC model.In the group with ≥2 components of MS cut-off point WC from the men was 93.3 cm (sensitivity 72%, specificity 83%), women – 90.2 cm (sensitivity 72%, specificity 62%).The lowest cut-off point WC marked BP ≥ 130/85 mm Hg for men – 90 cm (sensitivity 66.8%, specificity 58.1%), for women – 86.5 cm (sensitivity 71.0%, specificity 55.7%). The highest cut-off point from the defined patients with diabetes for men was 99.0 cm (sensitivity 61%, specificity 70.2%), for women – cm (sensitivity 64.1%, specificity 65.9%).Conclusions: Cut-off point from the persons with the presence of ≥2 MS components in Siberian population 45–69 years, in accordance with the ROC analysis are 93.3 cm for men and 90.2 cm for women. The lowest cut-off point WC marked BP ≥ 130/85 mm Hg for men – 90 cm, for women – 86.5 cm. The highest cut-off point from the defined patients with diabetes for men was 99.0 cm, for women – 95 cm.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>отрезная точка</kwd><kwd>окружность талии</kwd><kwd>метаболический синдром</kwd><kwd>сахарный диабет</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cut-off point</kwd><kwd>waist circumference</kwd><kwd>metabolic syndrome</kwd><kwd>diabetes</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Гранты фонда Wellcome Trust  и Национального Института возраста США</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bouguerra R., Alberti H., Smida H., Salem L.B. Waist circumference cut-off points for identification of abdominal obesity among the tunisian adult population // Diabetes, Obesity and Metabolism. 2007. V. 9, iss. 6. P. 859–868.</mixed-citation><mixed-citation xml:lang="en">Bouguerra R., Alberti H., Smida H., Salem L.B. Waist circumference cut-off points for identification of abdominal obesity among the tunisian adult population. Diabetes, Obesity and Metabolism, 2007, vol. 9, iss. 6, pp. 859–868.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Hara K., Matsushita Y., Horikoshi M., Yoshiike N. A proposal for the cut-off point of waist circumference for the diagnosis of metabolic syndrome in the Japanese population // Diabetes Care. 2006. V. 29. P. 1123–1124.</mixed-citation><mixed-citation xml:lang="en">Hara K., Matsushita Y., Horikoshi M., Yoshiike N. A proposal for the cutoff point of wais circumference for the diagnosis of metabolic syndrome in the Japanese population. Diabetes Care, 2006, vol. 29, pp. 1123–1124.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Mansour А.А., Al-Hassan А.А., Al-Jazairi M.I. Cut-off for waist circumference in rural Iragi adults for the diagnosis of metabolic syndrome // Rural and Remote Health. 2007. Р. 7765 (Online).</mixed-citation><mixed-citation xml:lang="en">Mansour А.А., Al-Hassan А.А., Al-Jazairi M.I. Cut-off for waist circumference in rural Iragi adults for the diagnosis of metabolic syndrome. Rural and Remote Health, 2007, pp. 7 765 (Online).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Miyatake N., Wada J., Matsumoto S., Nishikawa H. Re-evaluation of waist circumference in metabolic syndrome a comparison between Japanes men and women // Acta Med. Okayama. 2007. Vol. 61, № 3. P. 167–169.</mixed-citation><mixed-citation xml:lang="en">Miyatake  N.,  Wada  J.,  Matsumoto  S.  Nishikawa  H.  Reevaluation of waist circumference in metabolic syndrome a comparison between Japanes men and women. Acta Med. Okayama, 2007, vol. 61, no. 3, pp. 167–169.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Oka R., Kobayashi J., Yagi K., Tanii H., Miyamato S., Asano A., Hagishita T., Mori M., Moriuchi T., Kobayashi M., Katsuda S., Kawashiri M., Nohara A., Takeda Y., Mabuchi H., Yamagishi M. Reassessment of the cut-off values of waist circumference and visceral fat for identifying Japanese subjects at risk for the metabolic syndrome // Diabetes Res. Clin. Pract. 2008. V. 79. P. 474–481.</mixed-citation><mixed-citation xml:lang="en">Oka R., Kobayashi J., Yagi K., Tanii H., Miyamato S., Asano A., Hagishita T., Mori M., Moriuchi T., Kobayashi M., Katsuda S., Kawashiri M., Nohara A., Takeda Y., Mabuchi H., Yamagishi M. Reassessment of the cutoff values of waist circumference and visceral fat for identifying Japanese subjects at risk for the metabolic syndrome. Diabetes Res. Clin. Pract., 2008, vol. 79, pp. 474–481.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Alberti K.G.M.M., Eckel R.H., Grundy S.M., Zimmet P.Z. et al. Harmonizing the Metabolic Syndrome // Circulation. 2009. V. 120. P. 1640–1645.</mixed-citation><mixed-citation xml:lang="en">Alberti K.G.M.M., Eckel R.H., Grundy S.M., Zimmet P.Z. et al. Harmonizing the Metabolic Syndrome. Circulation, 2009, vol. 120, pp. 1640–1645.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Peasey A., Bobak M., Kubinova R., Malyutina S., Pajak A., Tamosiunas A., Pikhart H., Nicholson A., Marmot M. Determinants of cardiovascular disease and other noncommunicable diseases in Central and Eastern Europe: Rationale and design of the HAPIEE study. URL: http://www.biomedcentral.com/1471-2458/6/255</mixed-citation><mixed-citation xml:lang="en">Peasey A., Bobak M., Kubinova R., Malyutina S., Pajak A., Tamosiunas A., Pikhart H., Nicholson A., Marmot M. Determinants of cardiovascular disease and other noncommunicable diseases in Central and Eastern Europe: Rationale    and    design    of    the    HAPIEE    study.    URL: http://www.biomedcentral.com/1471-2458/6/255</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Expert Panel on Detection Evaluation, and treatment of high blood cholesterol in adults: Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Jama 285. 2001. P. 2486–2497.</mixed-citation><mixed-citation xml:lang="en">Expert Panel on Detection Evaluation, and treatment of high blood cholesterol in adults: Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Jama 285. 2001. P. 2486–2497.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Heshmat R., Khashayar P., Meybodi H.R.A., Homami M.R., Larijani B. The Appropriate Waist Circumference Cut-off for Iranian Population // Acta Med. Indones-Indones J. Intern. Med. 2010. Oct. V. 42, № 4. P. 209–215.</mixed-citation><mixed-citation xml:lang="en">Heshmat R., Khashayar P., Meybodi H.R.A., Homami M.R., Larijani B. The Appropriate Waist Circumference Cut-offfor Iranian Population. Acta Med. Indones-Indones J. Intern. Med., 2010, Oct., vol. 42, no. 4, pp. 209–215.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Zhou B.F. Predictive values of body mass index and waist circumference for risk factors of certain related diseases in Chinese adults-study on optimal cut-off points of body mass index and waist circumference in Chinese adults. Cooperative Meta-Analysis Group of the Working Group on Obesity in China // Biomed Environ Sci. 2002. Mar. V. 15, № 1. P. 83–96.</mixed-citation><mixed-citation xml:lang="en">Zhou B.F. Predictive values of body mass index and waist circumference for risk factors of certain related diseases in Chinese adults-study on optimal cut-off points of body mass index and waist circumference in Chinese adults.Cooperative Meta-Analysis Group of the Working Group on Obesity in China.  Biomed.  Environ  Sci.,  2002,  Mar.,  vol. 15,  no. 1, pp. 83–96.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Delavari A., Forouzanfar M.H., Alikhani S., Sharifian A., Kelishadi R. First Nationwide Study of the Prevalence of the Metabolic Syndrome and Optimal cut-off Points of Waist Circumference in the Middle Eas // Diabetes Care. 2009. June. V. 32, № 6. P. 1092–1097. doi: 10.2337/dc08-1800.</mixed-citation><mixed-citation xml:lang="en">Delavari A., Forouzanfar M.H., Alikhani S., Sharifian A., Kelishadi R. First Nationwide Study of the Prevalence of the Metabolic Syndrome and Optimal cut-off Points of Waist Circumference  in  the  Middle  Eas.  Diabetes  Care,  2009, June, vol. 32, no. 6, pp. 1092–1097. doi:10.2337/dc08-1800</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Zaher Z.M.M., Zambari R., Pheng C.S., Muruga V., Ng B., Appannah G. Optimal cut-off levels to define obesity: body mass index and waist circumference, and their relationship to cardiovascular disease, dyslipidaemia, hypertension and diabetes in Malaysia // Asia Pac. J. Clin. Nutr. 2009. V. 18, № 2. P. 209–216.</mixed-citation><mixed-citation xml:lang="en">Zaher Z.M.M., Zambari R., Pheng C.S., Muruga V., Ng B., Appannah G. Optimal cut-off levels to define obesity: body mass index and waist circumference, and their relationship to cardiovascular disease, dyslipidaemia, hypertension and diabetes in Malaysia. Asia Pac. J. Clin. Nutr., 2009, vol. 18, no. 2, pp. 209–216.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Dobbelsteyn C.J., Joffres M.R., MacLean D.R., Flowerdew G. and The Canadian Heart Health Surveys Research Group. A comparative evaluation of waist circumference, waist-to-hip ratio and body mass index as indicatorsof cardiovascular risk factors // The Canadian Heart Health Surveys International Journal of Obesity. 2001. V. 25. P. 652–661.</mixed-citation><mixed-citation xml:lang="en">Dobbelsteyn C.J., Joffres M.R., MacLean D.R., Flowerdew G. and The Canadian Heart Health Surveys Research Group. A comparative evaluation of waist circumference, waist-to-hip ratio and body mass index as indicatorsof cardiovascular risk factors. The Canadian Heart Health Surveys International Journal of Obesity, 2001, vol. 25, pp. 652–661.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Lee S., Park H.S., Kim S.M., Kwon H.S., Kim D.Y., Kim D.J., Cho G.J., Han J.H., Kim S.R., Park C.Y., Oh S.J., Lee C.B., Kim K.S., Oh S.W., Kim Y.S., Choi W.H., Yoo H.J. Cut-off Points of Waist Circumference for Defining Abdominal Obesity in the Korean Population // Korean J. Obes. 2006. Mar. V. 15, № 1. P. 1–9.</mixed-citation><mixed-citation xml:lang="en">Lee S., Park H.S., Kim S.M., Kwon H.S., Kim D.Y., Kim D.J., Cho G.J., Han J.H., Kim S.R., Park C.Y., Oh S.J., Lee C.B., Kim K.S., Oh S.W., Kim Y.S., Choi W.H., Yoo H.J. Cut-off Points of Waist Circumference for Defining Abdominal Obesity in the Korean Population. Korean J. Obes., 2006, Mar., vol. 15, no. 1, pp. 1–9.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Tan C.E., Ma S., Wai D. Can we apply the National Cholesterol Education Program Adult Treatment Panel definition of the metabolic syndrome to Asians? // Diabetes Care. 2004. 27. Р. 1182–1186.</mixed-citation><mixed-citation xml:lang="en">Tan C.E., Ma S., Wai D. Can we apply the National Cholesterol Education Program Adult Treatment Panel definition of the metabolic syndrome to Asians? Diabetes Care, 2004, 27, pp. 1182–1186.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Alberti K.G., Zimmet P., Shaw J. IDF Epidemiology Task Force Consensus Group. The metabolic syndrome a new worldwide definition // Lancet. 2005. 366. Р. 1059–1062.</mixed-citation><mixed-citation xml:lang="en">Alberti K.G., Zimmet P., Shaw J. IDF Epidemiology Task Force  Consensus  Group.  The  metabolic  syndrome  a  new worldwide definition. Lancet, 2005, 366, pp. 1059–1062.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Deurenberg-Yap M., Chew S.K., Lin V.F. Relationships between indices of obesity and its comorbidities in multi-ethnic Singapore // Int. J. Obes. Relat. Metab. Disord. 2001. 25. Р. 1554–1562.</mixed-citation><mixed-citation xml:lang="en">Deurenberg-Yap M., Chew S.K., Lin V.F. Relationships between indices of obesity and its comorbidities in multi-ethnic Singapore.  Int. J. Obes. Relat. Metab. Disord., 2001, 25, pp. 1554–1562.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">International Obesity Task Force. Asia–Pacific perspective: redefining obesity and its treatment. Western Pacific Region Sydney. Australia. 2000.</mixed-citation><mixed-citation xml:lang="en">International Obesity Task Force. Asia–Pacific perspective: redefining obesity and its treatment. Western Pacific Region Sydney, Australia, 2000.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Examination Committee of Criteria for ‘Obesity Disease’ in Japan; Japan Society for the Study of Obesity. New criteria for ‘obesity disease’ in Japan // Circ. J. 2002. 66. Р. 987–992.</mixed-citation><mixed-citation xml:lang="en">Examination Committee of Criteria for ‘Obesity Disease’ in Japan; Japan Society for the Study of Obesity. New criteria for ‘obesity disease’ in Japan. Circ. J., 2002, 66, pp. 987–992.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Рекомендации экспертов всероссийского научного общества кардиологов по диагностике и лечению метаболического синдрома. Второй пересмотр. М.: 2009. С. 32.</mixed-citation><mixed-citation xml:lang="en">Рекомендации  экспертов  всероссийского  научного  общества кардиологов по диагностике и лечению метаболического синдрома. Второй пересмотр. М.: 2009. С. 32.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Климова Т.М., Федорова В.И., Балтахинова М.Е. Критерии ожирения для идентификации метаболических факторов риска у коренного сельского населения Якутии // Сиб. мед. журн. 2012. № 8. C. 110–113.</mixed-citation><mixed-citation xml:lang="en">Климова Т.М., Федорова В.И., Балтахинова М.Е. Критерии ожирения для идентификации метаболических факторов риска у коренного сельского населения Якутии // Сиб. мед. журн. 2012. № 8. C. 110–113.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
