Оn the basis of the heart rate variability analysis in 41 patients during acute period of nontraumatic intracranial hemorrhages it was revealed that dynamics of the vegetative dysfunction rise was characterized by transition from reflex to humoral metabolic type of regulation. The reduction of reactivity of vegetative nervous system parasympathetic part during respiratory and active orthostatic test was noted. The method of evaluation of vegetative nervous system reactivity by means of heart rate variability analysis recorded before, during and after lumbar puncture with measure of cerebrospinal fluid pressure was worked out. It allows to evaluate the reactivity of suprasegmental centers (adequate, insufficient, exhaustion), raises accuracy of detection of adaptive organism resources with the detachment of the disease course variant and helps to reveal correlation of exertion extent of suprasegmental centers with hypertensive hydrocephalic syndrome.