ssmuБюллетень сибирской медициныBulletin of Siberian Medicine1682-03631819-3684Siberian State Medical University, the Ministry of Healthcare of the Russian Federation10.20538/1682-0363-2004-2-13-20ssmu-3621Research ArticleЭКСПЕРИМЕНТАЛЬНЫЕ И КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯEXPERIMENTAL AND CLINICAL INVESTIGATIONSИммунный статус и функциональное состояние лимфоцитов при различных клинических вариантах задержки физического развития детей и подростков как результат иммуноэндокринной взаимосвязиImmune and functional states of lymphocytes in different clinical variants of physical growth and development retardation at children and teenagers as a result of immune-endocrine correlationСапринаТ. В.SaprinaT. V.

г. Томск

Tomsk

КравецЕ. Б.KravetsYe. B.

г. Томск

Tomsk

ОгородоваЛ. М.OgorodovaL. M.

г. Томск

Tomsk

Сибирский государственный медицинский университетРоссияSiberian State Medical UniversityRussian Federation200430062004321320Copyright © Саприна Т.В., Кравец Е.Б., Огородова Л.М., 20042004Саприна Т.В., Кравец Е.Б., Огородова Л.М.Saprina T.V., Kravets Y.B., Ogorodova L.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://bulletin.ssmu.ru/jour/article/view/3621

Для изучения гормонально-иммунологических взаимосвязей выбрана клиническая модель, включающая два варианта (соматотропная недостаточность и конституциональная задержка роста и пубертата) задержки физического развития у детей и подростков. Показано, что иммунологические изменения при этих вариантах низкорослости носят разнонаправленный характер, что отражает гормональные влияния на параметры иммунитета.

For the study of hormonic-immunologic correlation a clinical model has been chosen that included two variants (somatotrophic deficiency and constitutional growth and pubertate inhibition) of physical growth and development retardation at children and teenagers. It has been revealed that immunologic changes under these dwarfism variants were of different character that reflected the hormonic effects on immunity parameters.

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The authors declare that there are no conflicts of interest present.