ssmuБюллетень сибирской медициныBulletin of Siberian Medicine1682-03631819-3684Siberian State Medical University, the Ministry of Healthcare of the Russian Federation10.20538/1682-0363-2002-1-70-74ssmu-3863Research ArticleРЕЗУЛЬТАТЫ ИССЛЕДОВАНИЙ МОЛОДЫХ УЧЕНЫХ И СТУДЕНТОВTHE RESULTS OF YOUNG SCIENTISTS’ AND STUDENTS’ INVESTIGATIONSЦитокины и оксид азота при бронхиальной астмеCytokines and nitric oxide in case of bronchial asthmaПетровскийФ. И.PetrovskyF. I.

Томск

ПетровскаяЮ. А.PetrovskayaYu. A.

Томск

ОгородоваЛ. М.OgorodovaL. M.

Томск

СеребровВ. Ю.SerebrovV. Yu.

Томск

Сибирский государственный медицинский университетRussian Federation200230032002117074Copyright © Петровский Ф.И., Петровская Ю.А., Огородова Л.М., Серебров В.Ю., 20022002Петровский Ф.И., Петровская Ю.А., Огородова Л.М., Серебров В.Ю.Petrovsky F.I., Petrovskaya Y.A., Ogorodova L.M., Serebrov V.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://bulletin.ssmu.ru/jour/article/view/3863

Представлены современные данные о системе взаимосвязи ключевых цитокинов, регулирующих атопическое воспаление при бронхиальной астме, и оксида азота. Описаны эффекты интерлейкина-4 на синтез оксида азота. Приведены данные о влиянии оксида азота на синтез цитокинов и баланс Th1/Th2, нарушение которого лежит в основе реагинового иммунного ответа.

Complex interactions between nitric oxide and cytokines of atopic inflammation are presented. The effects of interleukin-4 on nitric oxide synthesis, immunoregulatory properties of nitric oxide and its influence on Th1/Th2 balance are described.

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The authors declare that there are no conflicts of interest present.