<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2008-0-26-33</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-3921</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МАТЕРИАЛЫ IV ВСЕРОССИЙСКОЙ НАУЧНО-ПРАКТИЧЕСКОЙ КОНФЕРЕНЦИИ «ФУНДАМЕНТАЛЬНЫЕ И ПРИКЛАДНЫЕ ИССЛЕДОВАНИЯ В ОНКОГЕМАТОЛОГИИ»</subject></subj-group></article-categories><title-group><article-title>Апоптоз и механизмы опухолевой прогрессии неходжкинских злокачественных лимфом</article-title><trans-title-group xml:lang="en"><trans-title>Apoptosis and mechanisms of tumoral progression non-Hodgkin’s malignant lymphomas</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ковынев</surname><given-names>И. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovynev</surname><given-names>I. B.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Поспелова</surname><given-names>Т. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Pospelova</surname><given-names>T. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Агеева</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ageyeva</surname><given-names>T. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дьячкова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Diyachcova</surname><given-names>N. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скворцова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Scvortsova</surname><given-names>N. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воропаева</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Voropayeva</surname><given-names>Ye. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Березина</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Berezina</surname><given-names>O. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нечунаева</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Nechounayeva</surname><given-names>I. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лямкина</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyamkina</surname><given-names>A. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Новосибирский государственный медицинский университет</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Городской гематологический центр, г. Новосибирск</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>МУЗ «Городская клиническая больница № 2», г. Новосибирск</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2008</year></pub-date><volume>7</volume><issue>0</issue><issue-title>Приложение 3</issue-title><fpage>26</fpage><lpage>33</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ковынев И.Б., Поспелова Т.И., Агеева Т.А., Дьячкова Н.В., Скворцова Н.В., Воропаева Е.Н., Березина О.В., Нечунаева И.Н., Лямкина А.С., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Ковынев И.Б., Поспелова Т.И., Агеева Т.А., Дьячкова Н.В., Скворцова Н.В., Воропаева Е.Н., Березина О.В., Нечунаева И.Н., Лямкина А.С.</copyright-holder><copyright-holder xml:lang="en">Kovynev I.B., Pospelova T.I., Ageyeva T.A., Diyachcova N.V., Scvortsova N.V., Voropayeva Y.N., Berezina O.V., Nechounayeva I.N., Lyamkina A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/3921">https://bulletin.ssmu.ru/jour/article/view/3921</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Воробьёв А.И. Руководство по гематологии: В 2 т./Под ред А.И. Воробьёва. М.: Ньюдиамед, 2003. Т. 2. 277 с.</mixed-citation><mixed-citation xml:lang="en">Воробьёв А.И. Руководство по гематологии: В 2 т./Под ред А.И. Воробьёва. М.: Ньюдиамед, 2003. Т. 2. 277 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Зенков А.Н., Скворцова Н.В., Черноловская Е.Л. и др. Определение и сравнение частоты встречаемости повышенного уровня экспрессии генов MDR1 и MRP у больных злокачественными лимфомами//Сб. тезисов международной рос.-норв. конф. гематологов. СПб., 2003. С. 73-74.</mixed-citation><mixed-citation xml:lang="en">Зенков А.Н., Скворцова Н.В., Черноловская Е.Л. и др. Определение и сравнение частоты встречаемости повышенного уровня экспрессии генов MDR1 и MRP у больных злокачественными лимфомами//Сб. тезисов международной рос.-норв. конф. гематологов. СПб., 2003. С. 73-74.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Криволапов Ю.А., Леенман У.У. Морфологическая диагностика лимфом. СПб.: КОСТА, 2006. 208 с.</mixed-citation><mixed-citation xml:lang="en">Криволапов Ю.А., Леенман У.У. Морфологическая диагностика лимфом. СПб.: КОСТА, 2006. 208 с.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Лушников Е.Ф., Абросимов Ф.Ю. Гибель клетки (апоптоз). М.: Медицина, 2001. 192 с.</mixed-citation><mixed-citation xml:lang="en">Лушников Е.Ф., Абросимов Ф.Ю. Гибель клетки (апоптоз). М.: Медицина, 2001. 192 с.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Мазуров В.И., Криволапов Ю.А. Классификация лимфом. Морфология, иммунофенотип, молекулярная генетика неходжкинских лимфом//Практ. онкогематология. 2004. Т. 5. № 3. С. 166-175.</mixed-citation><mixed-citation xml:lang="en">Мазуров В.И., Криволапов Ю.А. Классификация лимфом. Морфология, иммунофенотип, молекулярная генетика неходжкинских лимфом//Практ. онкогематология. 2004. Т. 5. № 3. С. 166-175.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Олейник Е.К., Донников М.Ю., Олейник В.М. Система апоптоза Fas-FasL в онкогенезе//Иммунология. 2004. № 4. C. 251-255.</mixed-citation><mixed-citation xml:lang="en">Олейник Е.К., Донников М.Ю., Олейник В.М. Система апоптоза Fas-FasL в онкогенезе//Иммунология. 2004. № 4. C. 251-255.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Петров С.В. Руководство по иммуногистохимической диагностике опухолей человека/Под ред. С.И. Петрова и Н.Т. Райхлина. Казань, 2004. 456 с.</mixed-citation><mixed-citation xml:lang="en">Петров С.В. Руководство по иммуногистохимической диагностике опухолей человека/Под ред. С.И. Петрова и Н.Т. Райхлина. Казань, 2004. 456 с.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Поспелова Т.И., Лосева М.И., Ковынев И.Б. и др. Основы опухолевой прогрессии гемобластозов//Бюл. СО РАМН. 2004. № 2. С. 73-76.</mixed-citation><mixed-citation xml:lang="en">Поспелова Т.И., Лосева М.И., Ковынев И.Б. и др. Основы опухолевой прогрессии гемобластозов//Бюл. СО РАМН. 2004. № 2. С. 73-76.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Райхлин Н.Т., Райхлин А.Н. Регуляция и проявления апоптоза в физиологических условиях и в опухолях//Руководство по иммуногистохимической диагностике опухолей человека/Под ред. С.И. Петрова и Н.Т. Райхлина. Казань: Титул, 2004. С. 350-366.</mixed-citation><mixed-citation xml:lang="en">Райхлин Н.Т., Райхлин А.Н. Регуляция и проявления апоптоза в физиологических условиях и в опухолях//Руководство по иммуногистохимической диагностике опухолей человека/Под ред. С.И. Петрова и Н.Т. Райхлина. Казань: Титул, 2004. С. 350-366.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Эллиниди В.Н., Аникеева Н.В., Максимова Н.А. Практическая иммуногистохимия//СПб.: ВЦЭРМ МЧС России, 2002. 36 с.</mixed-citation><mixed-citation xml:lang="en">Эллиниди В.Н., Аникеева Н.В., Максимова Н.А. Практическая иммуногистохимия//СПб.: ВЦЭРМ МЧС России, 2002. 36 с.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Coiffier B., Thieblemont C., Felman P., et al. Indolent nonfollicualr lymphomas: characteristics, treatment, and outcome//Semin. Hematol. 1999. V. 36. P. 198-208.</mixed-citation><mixed-citation xml:lang="en">Coiffier B., Thieblemont C., Felman P., et al. Indolent nonfollicualr lymphomas: characteristics, treatment, and outcome//Semin. Hematol. 1999. V. 36. P. 198-208.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Dang C.V., O'Donnel K.A., Juopperi T. The great MYC escape in tumorigenesis//Cancer Cell. 2005. Sep. V. 8 (3). P. 177-178.</mixed-citation><mixed-citation xml:lang="en">Dang C.V., O'Donnel K.A., Juopperi T. The great MYC escape in tumorigenesis//Cancer Cell. 2005. Sep. V. 8 (3). P. 177-178.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Ghielmini M. Mora O. Does the FLIPI apply to grade 3 follicular lymphoma?//Blood. 2005. June. V. 105. № 12. P. 4892-4893.</mixed-citation><mixed-citation xml:lang="en">Ghielmini M. Mora O. Does the FLIPI apply to grade 3 follicular lymphoma?//Blood. 2005. June. V. 105. № 12. P. 4892-4893.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Hayat M.A. Microscopy, immunohistohemistry, and antigen retrieval methods: for ligth and electron microscopy. N. Y.: Kluwer Academic; Plenum Publishers, 2002. 355 p.</mixed-citation><mixed-citation xml:lang="en">Hayat M.A. Microscopy, immunohistohemistry, and antigen retrieval methods: for ligth and electron microscopy. N. Y.: Kluwer Academic; Plenum Publishers, 2002. 355 p.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Hemann M.T., Bric A., Teruya-Feldstein J., et al. Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants//Nature. 2005. Aug. 11. V. 436 (7052). P. 807-811.</mixed-citation><mixed-citation xml:lang="en">Hemann M.T., Bric A., Teruya-Feldstein J., et al. Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants//Nature. 2005. Aug. 11. V. 436 (7052). P. 807-811.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Hyer M.L., Sudarshan S., Kim Y., et al. Down-regulation of c-FLIP sensitizes DU145 prostate cancer cells to fas-mediated apoptosis//Cancer Biol. Ther. 2002. V. 1. P. 405-406.</mixed-citation><mixed-citation xml:lang="en">Hyer M.L., Sudarshan S., Kim Y., et al. Down-regulation of c-FLIP sensitizes DU145 prostate cancer cells to fas-mediated apoptosis//Cancer Biol. Ther. 2002. V. 1. P. 405-406.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Kamihira S., Yamada Y., Tomonaga M., et al. Discrepant expression of membrane and soluble isoforms of Fas (CD95/APO-1) in adult T-cell leukaemia: soluble Fas isoform is an independent risk factor for prognosis//Br. J. Haematol. 1999. V. 107. P. 851-860.</mixed-citation><mixed-citation xml:lang="en">Kamihira S., Yamada Y., Tomonaga M., et al. Discrepant expression of membrane and soluble isoforms of Fas (CD95/APO-1) in adult T-cell leukaemia: soluble Fas isoform is an independent risk factor for prognosis//Br. J. Haematol. 1999. V. 107. P. 851-860.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Kojima Y., Tsurumi H., Goto N., et al. Fas and Fas ligand expression on germinal center type-diffuse large B-cell lymphoma is associated with the clinical outcome//Eur. J. Haematol. 2006, Jun. V. 76 (6). P. 465-472.</mixed-citation><mixed-citation xml:lang="en">Kojima Y., Tsurumi H., Goto N., et al. Fas and Fas ligand expression on germinal center type-diffuse large B-cell lymphoma is associated with the clinical outcome//Eur. J. Haematol. 2006, Jun. V. 76 (6). P. 465-472.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Osorio L.M., Aguilar-Santelises M., de Santiago A., et al. Increased serum levels of soluble Fax in progressive B-CLL//Eur. J. Haematol. 2001. V. 66. P. 342-346.</mixed-citation><mixed-citation xml:lang="en">Osorio L.M., Aguilar-Santelises M., de Santiago A., et al. Increased serum levels of soluble Fax in progressive B-CLL//Eur. J. Haematol. 2001. V. 66. P. 342-346.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Sonneveld P. Multidrug resistance in haematological malignancies//J. Int. Med. 2000. May. V. 247. P. 521-532.</mixed-citation><mixed-citation xml:lang="en">Sonneveld P. Multidrug resistance in haematological malignancies//J. Int. Med. 2000. May. V. 247. P. 521-532.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Thieblemont C., Bastion Y., Berger F., et al. Mucosa-associated lymphoid tissue gastrointestinal and non-gastrointestinal lymphoma behavior: analysis of 108 patients//J. Clin. Oncol. 1997. V. 15. P. 1624-1630.</mixed-citation><mixed-citation xml:lang="en">Thieblemont C., Bastion Y., Berger F., et al. Mucosa-associated lymphoid tissue gastrointestinal and non-gastrointestinal lymphoma behavior: analysis of 108 patients//J. Clin. Oncol. 1997. V. 15. P. 1624-1630.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">van Imhoff G.W., Boerma E.J., van der Holt B., et al. Prognostic impact of germinal center-associated proteins and chromosomal breakpoints in poor-risk diffuse large B-cell lymphoma//J. Clin. Oncol. 2006. Sep. 1. V. 24 (25). P. 4135-4142.</mixed-citation><mixed-citation xml:lang="en">van Imhoff G.W., Boerma E.J., van der Holt B., et al. Prognostic impact of germinal center-associated proteins and chromosomal breakpoints in poor-risk diffuse large B-cell lymphoma//J. Clin. Oncol. 2006. Sep. 1. V. 24 (25). P. 4135-4142.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
