<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2005-0-22-25</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-3943</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКСПЕРИМЕНТАЛЬНЫЕ И КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERIMENTAL AND CLINICAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Состояние гепатобилиарной системы при эндокринной патологии</article-title><trans-title-group xml:lang="en"><trans-title>State of hepatobiliary system at endocrinous pathology</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кравец</surname><given-names>Е. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Kravets</surname><given-names>Ye. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Томск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Медведев</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Medvedev</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Томск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колмацуй</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolmatsuj</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Томск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бирюлина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Birjulina</surname><given-names>Ye. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Томск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Сибирский государственный медицинский университет</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2005</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2005</year></pub-date><volume>4</volume><issue>0</issue><issue-title>Приложение 2</issue-title><fpage>22</fpage><lpage>25</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кравец Е.Б., Медведев М.А., Колмацуй И.А., Бирюлина Е.А., 2005</copyright-statement><copyright-year>2005</copyright-year><copyright-holder xml:lang="ru">Кравец Е.Б., Медведев М.А., Колмацуй И.А., Бирюлина Е.А.</copyright-holder><copyright-holder xml:lang="en">Kravets Y.B., Medvedev M.A., Kolmatsuj I.A., Birjulina Y.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/3943">https://bulletin.ssmu.ru/jour/article/view/3943</self-uri><abstract><p>Цель исследования – оценить клинико-патогенетические аспекты нарушений гепатобилиарной системы при ведущих эндокринных заболеваниях у детей и подростков.</p><p>Обследовано 140 детей и подростков с патологией щитовидной железы и 125 детей, больных сахарным диабетом (СД) 1 типа. Группу сравнения составили 30 детей. Оценивалось состояние гепатобилиарной системы, используя фракционное дуоденальное зондирование, биохимию желчи, УЗИ печени и желчного пузыря, динамическую гепатобилисцинтиграфию. Установлено, что при патологии щитовидной железы изменения со стороны гепатобилиарной системы больше зависят от функциональной характеристики щитовидной железы, чем от длительности заболевания. Изменения в биохимическом составе желчи при тиреопатиях были обусловлены нарушением моторики желчевыделения. При СД 1 типа клинико-функцио­нальные изменения со стороны гепатобилиарной системы имели место в 50% случаев, чаще всего диагностировался жировой гепатоз. Предложен комплекс диагностического обследования для уточнения патологии гепатобилиарной системы при эндокринопатиях.</p></abstract><trans-abstract xml:lang="en"><p>The aim of research is to estimate clinicopathologic aspects of hepatobiliary system abnormalities at leading endocrinous diseases among children and adolescents.</p><p>There were examined 140 children and adolescents with thyroid gland pathology and 125 children with diabetes mellitus of 1 type. Comparison group consists of 30 children. There was estimated hepatobiliary system condition using fractional duodenal intubation, bile biochemistry, US of liver and gall-bladder, dynamic radionuclide hepatobiliary imaging. It was determined that changes from side of hepatobiliary system depend mostly from functional characteristic of thyroid gland than from duration of disease at pathology of thyroid gland. Changes in biochemical composition of bile at thyreopathy were conditioned by abnormality of biliary excretion motor activity. Clinic-functional changes from hepatobiliary system occurred in 50% of cases and fatty hepatosis was mostly frequent diagnosed at SD of the 1st type. There were suggested complex of diagnostic examination in order to define pathology of hepatobiliary system at endocrinopathy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гепатобилиарная система</kwd><kwd>гормоны</kwd><kwd>сахарный диабет</kwd><kwd>тиреопатии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hepatobiliary system</kwd><kwd>hormones</kwd><kwd>a diabetes</kwd><kwd>thyreopathy.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
