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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2002-2-52-55</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-3951</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКСПЕРИМЕНТАЛЬНЫЕ И КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERIMENTAL AND CLINICAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Механизмы активации эндотелия у беременных с бронхиальной астмой и гестозом</article-title><trans-title-group xml:lang="en"><trans-title>The mechanisms of activization of endothelium at the pregnant patients with bronchial asthma and gestosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Махмутходжаев</surname><given-names>А. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Makhmutkhodzhaev</surname><given-names>A. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Томск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Огородова</surname><given-names>Л. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ogorodova</surname><given-names>L. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Томск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Радионченко</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Radionchenko</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Томск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евтушенко</surname><given-names>И. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Evtushenko</surname><given-names>I. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Томск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимошина</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Timoshina</surname><given-names>E. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Томск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасенко</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasenko</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Томск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Махмутходжаева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Makhmutkhodzhaeva</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Томск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Сибирский государственный медицинский университет</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2002</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2002</year></pub-date><volume>1</volume><issue>2</issue><fpage>52</fpage><lpage>55</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Махмутходжаев А.Ш., Огородова Л.М., Радионченко А.А., Евтушенко И.Д., Тимошина Е.Л., Тарасенко В.И., Махмутходжаева Е.В., 2002</copyright-statement><copyright-year>2002</copyright-year><copyright-holder xml:lang="ru">Махмутходжаев А.Ш., Огородова Л.М., Радионченко А.А., Евтушенко И.Д., Тимошина Е.Л., Тарасенко В.И., Махмутходжаева Е.В.</copyright-holder><copyright-holder xml:lang="en">Makhmutkhodzhaev A.S., Ogorodova L.M., Radionchenko A.A., Evtushenko I.D., Timoshina E.L., Tarasenko V.I., Makhmutkhodzhaeva E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/3951">https://bulletin.ssmu.ru/jour/article/view/3951</self-uri><abstract><p>У беременных женщин при развитии гестоза обнаружено увеличение концентрации в сыворотке крови растворимых молекул адгезии sVCAM-1 и sICAM-1. Аналогичные изменения выявлены у беременных с бронхиальной астмой при сроке гестации 18 нед. При этом отмечена положительная корреляция между содержанием растворимых молекул адгезии и концентрацией в сыворотке крови цитокинов атопического воспаления.</p></abstract><trans-abstract xml:lang="en"><p>At pregnant women with gestosis the increasing of concentration in blood serum of soluble molecules of adherence sVCAM-1 and sICAM-1 is discovered. The same changes are revealed at pregnant with bronchial asthma, the period of gestosis being 18 weeks. With it there is a positive correlation between the substance of soluble molecules of adherence and the concentration of cytokines of atopic inflammation in blood serum.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>молекулы адгезии</kwd><kwd>цитокины</kwd><kwd>бронхиальная астма</kwd><kwd>гестоз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>molecules of adherence</kwd><kwd>cytokines</kwd><kwd>bronchial asthma</kwd><kwd>gestisis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ветров В.В.//Акуш. гин. 2001. № 4. С. 7-9.</mixed-citation><mixed-citation xml:lang="en">Ветров В.В.//Акуш. гин. 2001. № 4. С. 7-9.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Махмутходжаев А.Ш., Радионченко А.А., Басанова Ю.А. и др.//Бюл. СО РАМН. 2001. № 1. 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