ssmuБюллетень сибирской медициныBulletin of Siberian Medicine1682-03631819-3684Siberian State Medical University, the Ministry of Healthcare of the Russian Federation10.20538/1682-0363-2005-0-56-60ssmu-3956Research ArticleОБЗОР ЛИТЕРАТУРЫLITERATURE REVIEWПроблемы иммунологической диагностики целиакии у детейProblems of immunologic diagnostics of celiac disease among childrenРославцеваЕ. А.RoslavtsevaYe. A.ЛысиковЮ. А.LysikovYu. А.

г. Москва

ЛавроваТ. Е.LavrovaТ. Ye.

г. Москва

БоровикТ. Э.BorovikТ. E.

г. Москва

Научный центр здоровья детей РАМНRussian FederationНИИ питания РАМНRussian Federation20053012200540Приложение 25660Copyright © Рославцева Е.А., Лысиков Ю.А., Лаврова Т.Е., Боровик Т.Э., 20052005Рославцева Е.А., Лысиков Ю.А., Лаврова Т.Е., Боровик Т.Э.Roslavtseva Y.A., Lysikov Y.А., Lavrova Т.Y., Borovik Т.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://bulletin.ssmu.ru/jour/article/view/3956

В обзоре рассмотрено значение определения сывороточных антител различных классов (IgA, IgG) к глиадину, ретикулину, эндомизиуму, тканевой трансглутаминазе для диагностики и скрининга при целиакии, достоинства и недостатки методов, особенности иммунологических реакций при целиакии у детей различного возраста, динамика титров антител на фоне соблюдения и нарушений безглютеновой диеты, место иммунологических методов в комплексной диагностике целиакии и для контроля за соблюдением диеты.

In the review it is observed the importance of determination of serum antibodies of different classes (IgA, IgG) to gliadine, reticulin, endomysium, tissue transglutaminase for diagnostics and screening under celiac disease, advantages and disadvantages of methods, peculiarities of immunologic reactions under celiac disease among children of different age, dynamics of titres of antibodies on the background of observance and non observance of gluten-free diet, place of immunologic methods in complex diagnostic of celiac disease and for control for diet observance.

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The authors declare that there are no conflicts of interest present.