<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2021-4-162-170</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-4593</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Возможности консервативного лечения пациентов с лимфедемой конечностей (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Possibilities of conservative treatment of patients with lymphedema of the extremities (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7564-8168</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мышенцев</surname><given-names>П. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Myshentsev</surname><given-names>P. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, доцент, кафедра и клиника госпитальной хирургии, </p><p>443099, г. Самара, ул. Чапаевская, 89</p></bio><bio xml:lang="en"><p>89, Chapaevskaya Str., Samara, 443099</p></bio><email xlink:type="simple">pnmy63@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5043-7193</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яровенко</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yarovenko</surname><given-names>G. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, кафедра и клиника госпитальной хирургии, </p><p>443099, г. Самара, ул. Чапаевская, 89</p></bio><bio xml:lang="en"><p>89, Chapaevskaya Str., Samara, 443099</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7473-6692</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каторкин</surname><given-names>С. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Katorkin</surname><given-names>S. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, доцент, кафедра и клиника госпитальной хирургии, </p><p>443099, г. Самара, ул. Чапаевская, 89</p></bio><bio xml:lang="en"><p>89, Chapaevskaya Str., Samara, 443099</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Самарский государственный медицинский университет (СамГМУ)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>03</day><month>01</month><year>2022</year></pub-date><volume>20</volume><issue>4</issue><fpage>162</fpage><lpage>170</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мышенцев П.Н., Яровенко Г.В., Каторкин С.Е., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Мышенцев П.Н., Яровенко Г.В., Каторкин С.Е.</copyright-holder><copyright-holder xml:lang="en">Myshentsev P.N., Yarovenko G.V., Katorkin S.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/4593">https://bulletin.ssmu.ru/jour/article/view/4593</self-uri><abstract><p>Представлен обзор литературных источников, посвященных различным методам лечения пациентов с лимфедемой конечностей. Статистические данные свидетельствуют о росте заболеваемости и инвалидизации пациентов с этой патологией. Вместе с тем возможности лечебных мероприятий при лимфедеме оставляют желать лучшего.</p><p>Анализ литературных данных показал, что основу лечения лимфедемы конечностей составляют комплексные консервативные мероприятия, которые должны обеспечить применение патогенетически обоснованных физических, механических и медикаментозных методов. В комплексных схемах консервативного лечения лимфатических отеков значительное место занимают физиотерапевтические методы. Ведущим среди них является регулярная комплексная противоотечная терапия. Этот метод признается ведущими специалистами в качестве основного в лечении пациентов с лимфедемой. Большое значение имеют приверженность пациентов к лечению, их социальная и психологическая поддержка. Выбор объема и метода оперативного вмешательства требует осуществления трудной, индивидуальной оценки патологических изменений, развивающихся при заболевании.</p><p>Несмотря на определенные достижения, результаты такого лечения далеки до удовлетворительных значений. Опыт большинства специалистов, занимающихся лимфедемой, свидетельствует о разумном балансе между базовой консервативной терапией и хирургическими способами лечения. Несомненно, результаты оценки этих методов позволят улучшить выбор оптимального метода лечения пациентов с лимфедемой конечностей. </p></abstract><trans-abstract xml:lang="en"><p>The literature review describes various methods for treating patients with lymphedema of the extremities. Statistics show an increase in the incidence and disability of patients with this pathology. However, the possibilities of therapeutic measures in lymphedema are far from perfect.</p><p>The analysis of literature data showed that the basis of treatment for lymphedema of the extremities is comprehensive conservative therapy with the use of pathogenetically grounded physical, mechanical, and medical methods. In complex schemes of conservative treatment for lymphedema, physiotherapy methods occupy a prominent place. The most common technique among them is regular combined decongestive therapy. This method is recognized by leading experts as the main one in treating patients with lower extremity lymphedema. Commitment of patients to treatment and their social and psychological counseling are of great importance. The choice of the volume and method of surgical intervention requires a difficult and individual assessment of pathological changes developing throughout the course of the disease.</p><p>Despite certain improvements in treatment methods, lower extremity lymphedema is still an unsolved issue. The experience of most specialists involved in lymphedema treatment demonstrates a reasonable balance between basic conservative and surgical treatment methods. Undoubtedly, results of evaluation of these methods will improve the choice of an optimal technique for treating patients with lymphedema of the extremities. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>лимфедема конечностей</kwd><kwd>консервативное лечение</kwd><kwd>физиотерапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lymphedema of the extremities</kwd><kwd>conservative treatment</kwd><kwd>physiotherapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Diagnosis and treatment of primary lymphedema. Consensus document of the International Union of Phlebology. International Angiology. 2010; 29 (5): 454–470.</mixed-citation><mixed-citation xml:lang="en">Diagnosis and treatment of primary lymphedema. Consensus document of the International Union of Phlebology. International Angiology. 2010; 29 (5): 454–470.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">The diagnosis and treatment of peripheral lymphedema: 2020 Consensus document of the International Society of Lymphology. Lymphology. 2020; 53 (1): 3–19.</mixed-citation><mixed-citation xml:lang="en">The diagnosis and treatment of peripheral lymphedema: 2020 Consensus document of the International Society of Lymphology. Lymphology. 2020; 53 (1): 3–19.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Rubio-Maicas C., Langhaus-Nixon J., Duarte Alfonso E., Alabajos Cea A., Forner-Cordero I. Maintenance treatment in lymphedema: review. The European Journal of Lymphology. 2013; 24 (67-68): 52–54.</mixed-citation><mixed-citation xml:lang="en">Rubio-Maicas C., Langhaus-Nixon J., Duarte Alfonso E., Alabajos Cea A., Forner-Cordero I. Maintenance treatment in lymphedema: review. The European Journal of Lymphology. 2013; 24 (67-68): 52–54.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Поташов Л.В., Бубнова Н.А., Орлов Р.С., Борисов А.В., Борисова Р.П., Петров С.В. Хирургическая лимфология. СПб.: ЛЭТИ, 2002: 272.</mixed-citation><mixed-citation xml:lang="en">Поташов Л.В., Бубнова Н.А., Орлов Р.С., Борисов А.В., Борисова Р.П., Петров С.В. Хирургическая лимфология. СПб.: ЛЭТИ, 2002: 272.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Золотухин И.А. Лимфедема нижних конечностей в клинической практике: возможности диагностики и лечения. Справочник поликлинического врача. 2006; 3: 243–254.</mixed-citation><mixed-citation xml:lang="en">Золотухин И.А. Лимфедема нижних конечностей в клинической практике: возможности диагностики и лечения. Справочник поликлинического врача. 2006; 3: 243–254.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Мышенцев П.Н., Каторкин С.Е. Тактика при вторичной лимфедеме нижних конечностей. Новости хирургии. 2014; 22 (2): 239–243. DOI: 10.18484/2305-0047.2014.2.239.</mixed-citation><mixed-citation xml:lang="en">Мышенцев П.Н., Каторкин С.Е. Тактика при вторичной лимфедеме нижних конечностей. Новости хирургии. 2014; 22 (2): 239–243. DOI: 10.18484/2305-0047.2014.2.239.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Бородин Ю.И., Любарский М.С., Морозов В.В. Руководство по клинической лимфологии. М.: Медицинское информационное агентство, 2010: 208.</mixed-citation><mixed-citation xml:lang="en">Бородин Ю.И., Любарский М.С., Морозов В.В. Руководство по клинической лимфологии. М.: Медицинское информационное агентство, 2010: 208.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Pereira de Godoy J. M. Quality of life and peripheral lymphedema. Lymphology. 2002; 35 (2): 72–75.</mixed-citation><mixed-citation xml:lang="en">Pereira de Godoy J. M. Quality of life and peripheral lymphedema. Lymphology. 2002; 35 (2): 72–75.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Torralba-Puebla T., Ortiz-Fernandez L., Zammaripa-Cuesta M. Patient education programm: school of lymphedema prevention. The European Journal of Lymphology. 2015; 27 (73): 25–27.</mixed-citation><mixed-citation xml:lang="en">Torralba-Puebla T., Ortiz-Fernandez L., Zammaripa-Cuesta M. Patient education programm: school of lymphedema prevention. The European Journal of Lymphology. 2015; 27 (73): 25–27.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Boccardo F. An overview of the treatment of primary and secondary lymphatic diseases: the effort of the ESL to put some order. The European Journal of Lymphology. 2017; 29 (77): 1–10.</mixed-citation><mixed-citation xml:lang="en">Boccardo F. An overview of the treatment of primary and secondary lymphatic diseases: the effort of the ESL to put some order. The European Journal of Lymphology. 2017; 29 (77): 1–10.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Caldirola R., Conti E., Bordoni M., Famoso L., Cestari M. Experience with siliconed bandages. The European Journal of Lymphology. 2017; 29 (77): 10–16.</mixed-citation><mixed-citation xml:lang="en">Caldirola R., Conti E., Bordoni M., Famoso L., Cestari M. Experience with siliconed bandages. The European Journal of Lymphology. 2017; 29 (77): 10–16.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Макарова В.С., Макаров И.Г., Спиридонов В.К. Консервативное лечение лимфедем: пособие для врачей. М.: ЛИМФА, 2011: 50.</mixed-citation><mixed-citation xml:lang="en">Макарова В.С., Макаров И.Г., Спиридонов В.К. Консервативное лечение лимфедем: пособие для врачей. М.: ЛИМФА, 2011: 50.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Pastouret F., Gilbert C., Colle M., Zirak C. CIRCAID®: pressures reproducibility with BPS® guide card (built-in pressure system). The European Journal of Lymphology. 2016; 28 (74): 66–69.</mixed-citation><mixed-citation xml:lang="en">Pastouret F., Gilbert C., Colle M., Zirak C. CIRCAID®: pressures reproducibility with BPS® guide card (built-in pressure system). The European Journal of Lymphology. 2016; 28 (74): 66–69.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Rel-Monzo P., BayarriI-Garcia V., Alabajos-Cea A., Tortosa-Soriano G., Sevilla-Perez B. Lymph Taping, complementary lymphoedema treatment? The European Journal of Lymphology. 2013; 24 (67-68): 56–58.</mixed-citation><mixed-citation xml:lang="en">Rel-Monzo P., BayarriI-Garcia V., Alabajos-Cea A., Tortosa-Soriano G., Sevilla-Perez B. Lymph Taping, complementary lymphoedema treatment? The European Journal of Lymphology. 2013; 24 (67-68): 56–58.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Ozsoy-Unubol T., Sanal-Toprak C., Bahar-Ozdemir Y., Akyuz G. Efficacy of kinesio taping in early stage breast cancer associated lymphedema: a randomized single blinded study. Lymphology. 2019; 52 (4): 166–176.</mixed-citation><mixed-citation xml:lang="en">Ozsoy-Unubol T., Sanal-Toprak C., Bahar-Ozdemir Y., Akyuz G. Efficacy of kinesio taping in early stage breast cancer associated lymphedema: a randomized single blinded study. Lymphology. 2019; 52 (4): 166–176.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Piller N. Mld and other treatments; how do we know they are working? The European Journal of Lymphology. 2013; 24 (67): 24–27.</mixed-citation><mixed-citation xml:lang="en">Piller N. Mld and other treatments; how do we know they are working? The European Journal of Lymphology. 2013; 24 (67): 24–27.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Мichelini S., Caldirola R., Forner Cordero I., Olszewski W., Pissas A., Dimakakos E., Michelotti L. Linforoll: a new device for lymphoedema treatment. Preliminary experience. The European Journal of Lymphology. 2013; 23 (67-68): 25–29.</mixed-citation><mixed-citation xml:lang="en">Мichelini S., Caldirola R., Forner Cordero I., Olszewski W., Pissas A., Dimakakos E., Michelotti L. Linforoll: a new device for lymphoedema treatment. Preliminary experience. The European Journal of Lymphology. 2013; 23 (67-68): 25–29.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Olszewski W.L., Zaleska M., Michelini S.: A new method for treatment of lymphedema of limbs: standardized manual massage with a new device linforoll in conservative and surgical therapy protocols. Lymphat. Res. Biol. 2016 Dec.; 14 (4): 226–232. DOI: 10.1089/lrb.2015.0034.</mixed-citation><mixed-citation xml:lang="en">Olszewski W.L., Zaleska M., Michelini S.: A new method for treatment of lymphedema of limbs: standardized manual massage with a new device linforoll in conservative and surgical therapy protocols. Lymphat. Res. Biol. 2016 Dec.; 14 (4): 226–232. DOI: 10.1089/lrb.2015.0034.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Gonzales-Castro C. Brief overview of the benefits of Nordic walking in the treatment of primary and secondary lymphedema. The European Journal of Lymphology. 2013; 24 (69): 28–30.</mixed-citation><mixed-citation xml:lang="en">Gonzales-Castro C. Brief overview of the benefits of Nordic walking in the treatment of primary and secondary lymphedema. The European Journal of Lymphology. 2013; 24 (69): 28–30.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Малинин А.А. Современная концепция тактики консервативного и сочетанного лечения лимфедемы конечностей. Ангиология и сосудистая хирургия. 2005; 11 (2): 61–69.</mixed-citation><mixed-citation xml:lang="en">Малинин А.А. Современная концепция тактики консервативного и сочетанного лечения лимфедемы конечностей. Ангиология и сосудистая хирургия. 2005; 11 (2): 61–69.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Wigg J. A pilot randomized control trial to compare a new intermittent pneumatic compression device and 12-chamber garment with current best practice in the management of limb lymphedema. The European Journal of Lymphology. 2009; 20 (58): 16–23.</mixed-citation><mixed-citation xml:lang="en">Wigg J. A pilot randomized control trial to compare a new intermittent pneumatic compression device and 12-chamber garment with current best practice in the management of limb lymphedema. The European Journal of Lymphology. 2009; 20 (58): 16–23.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Theys S., Hennequart T., Aguillar Ferrandiz M. E, Deltombe T. Press pneumatic drainage versus manual drainage In upper limb secondary lymphedema. Same compression, same benefit? The European Journal of Lymphology. 2015; 27 (73): 6–8.</mixed-citation><mixed-citation xml:lang="en">Theys S., Hennequart T., Aguillar Ferrandiz M. E, Deltombe T. Press pneumatic drainage versus manual drainage In upper limb secondary lymphedema. Same compression, same benefit? The European Journal of Lymphology. 2015; 27 (73): 6–8.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Olszewski W.L., Pradeep J., Zaleska M., Cacala M., Gradalski T., Szopinska S. Hydraulics of the tissue fluid during pneumatic compression in the lymphedema of lower limbs. The European Journal of Lymphology. 2011; 22 (64): 14–19.</mixed-citation><mixed-citation xml:lang="en">Olszewski W.L., Pradeep J., Zaleska M., Cacala M., Gradalski T., Szopinska S. Hydraulics of the tissue fluid during pneumatic compression in the lymphedema of lower limbs. The European Journal of Lymphology. 2011; 22 (64): 14–19.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Zaleska M., Olszewski W.L., Cakala M. Five-ears of intermittent pneumatic compression in postinflammatory, posttraumatic and post-cancer- therapy edema of lower limbs. The European Journal of Lymphology. 2017; 29 (76): 34–38.</mixed-citation><mixed-citation xml:lang="en">Zaleska M., Olszewski W.L., Cakala M. Five-ears of intermittent pneumatic compression in postinflammatory, posttraumatic and post-cancer- therapy edema of lower limbs. The European Journal of Lymphology. 2017; 29 (76): 34–38.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Жуков Б.Н. Патофизиологические аспекты хронической лимфовенозной недостаточности нижних конечностей. Самара: Офорт, 2008: 279.</mixed-citation><mixed-citation xml:lang="en">Жуков Б.Н. Патофизиологические аспекты хронической лимфовенозной недостаточности нижних конечностей. Самара: Офорт, 2008: 279.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Izzo M., Napolitano L., Coscia V., La Gatta A., Mariani F., Gasparro V. The role of diamagnetic pump (CTU mega 18) in the physical treatment of limbs lymphoedema. A clinical study. The European Journal of Lymphology. 2010; 21 (61): 3–8.</mixed-citation><mixed-citation xml:lang="en">Izzo M., Napolitano L., Coscia V., La Gatta A., Mariani F., Gasparro V. The role of diamagnetic pump (CTU mega 18) in the physical treatment of limbs lymphoedema. A clinical study. The European Journal of Lymphology. 2010; 21 (61): 3–8.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Жуков Б.Н., Лысов Н.А., Анисимов В.И. Лазерные технологии в медицине. Самара, 2001: 224.</mixed-citation><mixed-citation xml:lang="en">Жуков Б.Н., Лысов Н.А., Анисимов В.И. Лазерные технологии в медицине. Самара, 2001: 224.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Бубнова Н.А., Борисова Р.П., Борисов А.В. Теория лимфангиона и современные подходы к патогенезу, диагностике и лечению лимфедемы нижних конечностей. Ангиология и сосудистая хирургия. 2003; 9 (2): 66–70.</mixed-citation><mixed-citation xml:lang="en">Бубнова Н.А., Борисова Р.П., Борисов А.В. Теория лимфангиона и современные подходы к патогенезу, диагностике и лечению лимфедемы нижних конечностей. Ангиология и сосудистая хирургия. 2003; 9 (2): 66–70.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Фионик О.В., Бубнова Н.А., Петров С.В., Ерофеев Н.П., Ладожская-Гапеенко Е.Е., Семенов А.Ю. Лимфедема нижних конечностей: алгоритм диагностики и лечения. Новости хирургии. 2009; 17 (4): 49–64.</mixed-citation><mixed-citation xml:lang="en">Фионик О.В., Бубнова Н.А., Петров С.В., Ерофеев Н.П., Ладожская-Гапеенко Е.Е., Семенов А.Ю. Лимфедема нижних конечностей: алгоритм диагностики и лечения. Новости хирургии. 2009; 17 (4): 49–64.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Котельников Г.П., Яшков А.В., Махова А.Н., Макаров И.В., Котельников М.Г. Экспериментальное обоснование гравитационной терапии. М.: Медицина, 2005: 277.</mixed-citation><mixed-citation xml:lang="en">Котельников Г.П., Яшков А.В., Махова А.Н., Макаров И.В., Котельников М.Г. Экспериментальное обоснование гравитационной терапии. М.: Медицина, 2005: 277.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Мышенцев П.Н., Жуков Б.Н., Каторкин С.Е., Яровенко Г.В., Шишкина А.А. Комплексное лечение больных с лимфедемой нижних конечностей с использованием установки гравитационной терапии. Вестник лимфологии. 2011; 3: 37–41.</mixed-citation><mixed-citation xml:lang="en">Мышенцев П.Н., Жуков Б.Н., Каторкин С.Е., Яровенко Г.В., Шишкина А.А. Комплексное лечение больных с лимфедемой нижних конечностей с использованием установки гравитационной терапии. Вестник лимфологии. 2011; 3: 37–41.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Bordoni M., Cestari M., Conti E., Famoso L. Lymphedema and lipedema: usefulness of shock иwaves. The European Journal of Lymphology. 2014; 25 (71): 49–53.</mixed-citation><mixed-citation xml:lang="en">Bordoni M., Cestari M., Conti E., Famoso L. Lymphedema and lipedema: usefulness of shock иwaves. The European Journal of Lymphology. 2014; 25 (71): 49–53.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Casley-Smith J.R., Piller N.B. The mode of action of coumarin and related compounds in the treatment of lymphedema. Stuttgart: Thieme, 1977: 33–41.</mixed-citation><mixed-citation xml:lang="en">Casley-Smith J.R., Piller N.B. The mode of action of coumarin and related compounds in the treatment of lymphedema. Stuttgart: Thieme, 1977: 33–41.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Clodius L., Piller N.B. The conservative treatement of postmastectomy lymphedema patients with coumarine results in a marked continious reduction in arm swelling. Advances in lymphology: V. Bartos (ed.). Prague: Avicenum, 1982: 471–474.</mixed-citation><mixed-citation xml:lang="en">Clodius L., Piller N.B. The conservative treatement of postmastectomy lymphedema patients with coumarine results in a marked continious reduction in arm swelling. Advances in lymphology: V. Bartos (ed.). Prague: Avicenum, 1982: 471–474.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Piller N.B. Consrevative treatement of acute chronic lymphedema with benzopyrones. Lymphology. 1976; 9 (4): 132–139.</mixed-citation><mixed-citation xml:lang="en">Piller N.B. Consrevative treatement of acute chronic lymphedema with benzopyrones. Lymphology. 1976; 9 (4): 132–139.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Michelini S., Fiorentino A., Cardone M. Melilotus, rutin and bromelain in primary and secondary lymphedema. Lymphology. 2019; 52 (4): 177–186.</mixed-citation><mixed-citation xml:lang="en">Michelini S., Fiorentino A., Cardone M. Melilotus, rutin and bromelain in primary and secondary lymphedema. Lymphology. 2019; 52 (4): 177–186.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Oliva E., Sarcinella R .An association of immune-modulators and natural lympho-kinetics in the treatment of posmastectomy lymphedema. A observational study. The European Journal of Lymphology. 2014; 25 (70): 20–24.</mixed-citation><mixed-citation xml:lang="en">Oliva E., Sarcinella R .An association of immune-modulators and natural lympho-kinetics in the treatment of posmastectomy lymphedema. A observational study. The European Journal of Lymphology. 2014; 25 (70): 20–24.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Warren A.G. Lymphedema: a comprehensive review. Ann. Plast. Surg. 2007; 59 (4): 464–472. DOI: 10.1097/01.SAP.0000257149.42922.7E.</mixed-citation><mixed-citation xml:lang="en">Warren A.G. Lymphedema: a comprehensive review. Ann. Plast. Surg. 2007; 59 (4): 464–472. DOI: 10.1097/01.SAP.0000257149.42922.7E.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Benda K., Bendova M. Patients’ self-treatment – Why and How? The European Journal of Lymphology. 2008; 19 (54): 6–9.</mixed-citation><mixed-citation xml:lang="en">Benda K., Bendova M. Patients’ self-treatment – Why and How? The European Journal of Lymphology. 2008; 19 (54): 6–9.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Ridner S.H., Fu M.R., Wanchai A., Stewart B.R., Armer J.M., Cormier J.N: Self-management of lymphedema. A systematic review of the literature from 2004 to 2011. Nursing Research. 2012; 61 (4): 291–299. DOI: 10.1097/NNR.0b013e31824f82b2.</mixed-citation><mixed-citation xml:lang="en">Ridner S.H., Fu M.R., Wanchai A., Stewart B.R., Armer J.M., Cormier J.N: Self-management of lymphedema. A systematic review of the literature from 2004 to 2011. Nursing Research. 2012; 61 (4): 291–299. DOI: 10.1097/NNR.0b013e31824f82b2.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Tzani I., Tsichlaki M., Zerva E., Papathanasiou G., Dimakakos E. Physiotherapeutic rehabilitation of lymphedema: stateof-the-art. Lymphology. 2018; 51 (1): 1–12.</mixed-citation><mixed-citation xml:lang="en">Tzani I., Tsichlaki M., Zerva E., Papathanasiou G., Dimakakos E. Physiotherapeutic rehabilitation of lymphedema: stateof-the-art. Lymphology. 2018; 51 (1): 1–12.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
