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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2023-1-170-173</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-5148</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ КЛИНИЧЕСКОЙ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Клинический случай психического расстройства на фоне новой коронавирусной инфекции</article-title><trans-title-group xml:lang="en"><trans-title>A clinical case of co-occurring mental disorder and coronavirus infection</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5162-0870</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джумагалиева</surname><given-names>М. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Jumagaliyeva</surname><given-names>M. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Джумагалиева Мерей Бакытжановна – Ph.D. 3-года обучения по специальности «Медицина»</p><p>030012, г. Актобе, ул. Маресьева, 68</p></bio><bio xml:lang="en"><p>68, Maresyeva Str., Aktobe, 030012</p></bio><email xlink:type="simple">aliyevamerey7@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1694-8301</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аяганов</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ayaganov</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аяганов Динмухамед Нурныязович – Ph.D., руководитель кафедры неврологии с курсом психиатрии и наркологии</p><p>030012, г. Актобе, ул. Маресьева, 68</p></bio><bio xml:lang="en"><p>68, Maresyeva Str., Aktobe, 030012</p></bio><email xlink:type="simple">dimash.83@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7387-138X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юлдашев</surname><given-names>В. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Yuldashev</surname><given-names>V. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юлдашев Владимир Лабибович – доктор медицинских наук, профессор, зав. кафедрой психиатрии и наркологии с курсом Института дополнительного профессионального образования</p><p>450008, Республика Башкортостан, г. Уфа, ул. Ленина, 3</p></bio><bio xml:lang="en"><p>3, Lenina Str., Ufa, Republic of Bashkortostan, 450008</p></bio><email xlink:type="simple">uvlprof@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1177-6424</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахмадеева</surname><given-names>Л. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Akhmadeeva</surname><given-names>L. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ахмадеева Лейла Ринатовна – доктор медицинских наук, профессор кафедры неврологии</p><p>450008, Республика Башкортостан, г. Уфа, ул. Ленина, 3</p></bio><bio xml:lang="en"><p>3, Lenina Str., Ufa, Republic of Bashkortostan, 450008</p></bio><email xlink:type="simple">Leila_ufa@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Западно-Казахстанский медицинский университет им. М. Оспанова</institution><country>Казахстан</country></aff><aff xml:lang="en"><institution>West Kazakhstan Marat Ospanov Medical University</institution><country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Башкирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>21</day><month>04</month><year>2023</year></pub-date><volume>22</volume><issue>1</issue><fpage>170</fpage><lpage>173</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Джумагалиева М.Б., Аяганов Д.Н., Юлдашев В.Л., Ахмадеева Л.Р., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Джумагалиева М.Б., Аяганов Д.Н., Юлдашев В.Л., Ахмадеева Л.Р.</copyright-holder><copyright-holder xml:lang="en">Jumagaliyeva M.B., Ayaganov D.N., Yuldashev V.L., Akhmadeeva L.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/5148">https://bulletin.ssmu.ru/jour/article/view/5148</self-uri><abstract><p>В новом тысячелетии человечество столкнулось с глобальной проблемой – новой коронавирусной инфекции COVID-19, вызванной вирусом SARS-CoV-2. Помимо системных и респираторных симптомов, вирус SARS-CoV-2 вызывает неврологические расстройства, так как обладает нейротропностью. Многие ученые предполагают, что SARS-CoV-2 способен проникать в нервную систему через функциональный рецептор ангиотензин-превращающего фермента 2, который присутствует в глиальных клетках, нейронах, скелетных мышцах и других органах. Осложнения со стороны нервной системы проявлялись поражениями различных структур: центральной нервной системы, периферической нервной системы и черепно-мозговых нервов, а также психическими расстройствами. Психические заболевания развиваются вследствие нейровоспаления и гибели нейронов после заражения мозга SARS-CoV-2.</p><p>Описан клинический случай новой коронавирусной инфекции у мужчины 63 лет с впервые выявленным психическим расстройством. Приведенный клинический пример демонстрирует важность изучения причинно-следственной связи между COVID-19 и психическим заболеванием. В среднесрочной и долгосрочной перспективе ожидается, что COVID-19 приведет к проблемам психического здоровья в период постковидного восстановления, также ожидается увеличение количества пациентов с психическими расстройствами, которые были психически здоровы до заражения COVID-19.</p></abstract><trans-abstract xml:lang="en"><p>(COVID-19). In addition to systemic and respiratory symptoms, SARS-CoV-2 causes neurological disorders, as it is a neurotropic virus. Many scientists assume that SARS-CoV-2 can enter the nervous system through the functional receptor of angiotensin-converting enzyme 2, which is present in glial cells, neurons, skeletal muscles, and other organs. Neurological complications are manifested by damage to the central nervous system, peripheral nervous system, and cranial nerves, as well as by mental disorders. Mental illnesses develop due to neuroinflammation and neuronal death after brain infection with SARS-CoV-2.</p><p>The article describes a clinical case of a 63-year-old man with the co-occurring novel coronavirus infection and obvious mental disorder who has never had any mental illnesses before. The given clinical example demonstrates the importance of studying the cause-and-effect relationship between COVID-19 and mental illness. In the mediumand long-term perspective, COVID-19 is expected to result in mental health disorders during COVID-19 recovery. Besides, an increase in the number of patients with mental disorders who were mentally healthy before COVID-19 infection is also expected.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>SARS-COV-2</kwd><kwd>COVID-19</kwd><kwd>коронавирус</kwd><kwd>психические заболевания</kwd><kwd>психические расстройства</kwd></kwd-group><kwd-group xml:lang="en"><kwd>SARS-COV-2</kwd><kwd>COVID-19</kwd><kwd>coronavirus</kwd><kwd>mental illnesses</kwd><kwd>mental disorders</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Iadecola C., Anrather J., Kamel H. Effects of COVID-19 on the nervous system. Cell. 2020;183(1):16–27.e1. DOI: 10.1016/j. cell.2020.08.028.</mixed-citation><mixed-citation xml:lang="en">Iadecola C., Anrather J., Kamel H. Effects of COVID-19 on the nervous system. Cell. 2020;183(1):16–27.e1. 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