<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2023-2-176-181</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-5235</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ КЛИНИЧЕСКОЙ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Мигренозный инсульт: клиническое наблюдение</article-title><trans-title-group xml:lang="en"><trans-title>A clinical case of migrainous stroke</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5528-1634</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Плотников</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Plotnikov</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Плотников Денис Маркович – канд. мед. наук, доцент кафедры неврологии и нейрохирургии, </p><p>634050, г. Томск, Московский тракт, 2</p></bio><bio xml:lang="en"><p>2, Moscow Trakt, Tomsk, 634050</p></bio><email xlink:type="simple">dmarkych@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4140-3223</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алифирова</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Alifirova</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алифирова Валентина Михайловна – д-р мед. наук, профессор, зав. кафедрой неврологии и нейрохирургии; гл. внештатный специалист – главный невролог Департамента здравоохранения Томской области, </p><p>634050, г. Томск, Московский тракт, 2</p></bio><bio xml:lang="en"><p>2, Moscow Trakt, Tomsk, 634050</p></bio><email xlink:type="simple">v_alifirova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мосиенко</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Mosienko</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мосиенко Елизавета Сергеевна – врач-невролог, неврологическое отделение, </p><p>634063, г. Томск, ул. И. Черных, 96</p></bio><bio xml:lang="en"><p>96, I. Chenykh Str., Tomsk, 634063</p></bio><email xlink:type="simple">mrs.lobanova5@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Сибирский государственный медицинский университет (СибГМУ)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Siberian State Medical University (SSMU)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Томская областная клиническая больница (ТОКБ)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tomsk Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>10</day><month>07</month><year>2023</year></pub-date><volume>22</volume><issue>2</issue><fpage>176</fpage><lpage>181</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Плотников Д.М., Алифирова В.М., Мосиенко Е.С., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Плотников Д.М., Алифирова В.М., Мосиенко Е.С.</copyright-holder><copyright-holder xml:lang="en">Plotnikov D.M., Alifirova V.M., Mosienko E.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/5235">https://bulletin.ssmu.ru/jour/article/view/5235</self-uri><abstract><p>Мигренозный инсульт – это редкое сочетание часто встречающихся заболеваний, в отечественной литературе описаны лишь единичные наблюдения. Сложность дифференциальной диагностики связана с тем, что на этапе начальных проявлений эти два состояния могут имитировать друг друга. Лечебная тактика и дальнейшая профилактика при каждом из этих заболеваний различны, поэтому так важна своевременная и убедительная диагностика на ранних этапах.</p><p>В представленном клиническом наблюдении описан случай ишемического инсульта у молодой женщины, длительное время страдающей мигренью, который не вполне соответствовал критериям мигренозного инфаркта. Пациентка лечилась в региональном сосудистом центре Томской областной клинической больницы, отмечена положительная динамика в неврологическом статусе. Отслежен катамнез заболевания. Высказано предположение о том, что эндотелиальная дисфункция – основный патогенетический фактор формирования ишемического очага на фоне затянувшегося мигренозного приступа.</p></abstract><trans-abstract xml:lang="en"><p>Migrainous stroke is a rare combination of frequently occurring diseases; only a few cases have been described in the domestic literature. The complexity of differential diagnosis is due to the fact that at the stage of initial manifestations, these two conditions can mimic each other. Treatment strategy and further prevention for each of these diseases is different, so timely and convincing early diagnosis is crucial. The presented clinical case describes a case of ischemic stroke in a young woman who had been suffering from migraine for a long time, which did not fully meet the criteria for migrainous infarction. The patient was treated at the regional vascular center of the Tomsk Regional Clinical Hospital, there was a positive trend in the neurological status. The catamnesis of the disease was tracked. It was suggested that endothelial dysfunction is the main pathogenetic factor in the formation of an ischemic focus against the background of a protracted migraine attack.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>мигрень</kwd><kwd>ишемический инсульт</kwd><kwd>мигренозный инфаркт</kwd></kwd-group><kwd-group xml:lang="en"><kwd>migraine</kwd><kwd>ischemic stroke</kwd><kwd>migrainous infarction</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Табеева Г.Р. Цереброваскулярные расстройства, ассоциированные с мигренью. Медицинский совет. 2017;(10):32–35.</mixed-citation><mixed-citation xml:lang="en">Табеева Г.Р. Цереброваскулярные расстройства, ассоциированные с мигренью. Медицинский совет. 2017;(10):32–35.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">The international classification of headache; 3rd ed. Cephalalgia. 2018;38(1):1–211. DOI: 10.1177/0333102417738202.</mixed-citation><mixed-citation xml:lang="en">The international classification of headache; 3rd ed. Cephalalgia. 2018;38(1):1–211. DOI: 10.1177/0333102417738202.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Gryglas A., Smigiel R. Migraine and Stroke: What’s the Link? What to do? Curr. Neurol. Neurosci. Rep. 2017;17(3):22. DOI: 10.1007/s11910-017-0729-y.</mixed-citation><mixed-citation xml:lang="en">Gryglas A., Smigiel R. Migraine and Stroke: What’s the Link? What to do? Curr. Neurol. Neurosci. Rep. 2017;17(3):22. DOI: 10.1007/s11910-017-0729-y.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Etminan M., Takkouche B., Isorna F.C., Samii A. Risk of ischaemic stroke in people with migraine: systematic review and meta-analysis of observational studies. BMJ. 2005;330(7482):63–65. DOI: 10.1136/bmj.38302.504063.8F.</mixed-citation><mixed-citation xml:lang="en">Etminan M., Takkouche B., Isorna F.C., Samii A. Risk of ischaemic stroke in people with migraine: systematic review and meta-analysis of observational studies. BMJ. 2005;330(7482):63–65. DOI: 10.1136/bmj.38302.504063.8F.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Schurks M., Rist P.M., Bigal M.E., Buring J.E., Lipton R.B., Kurth T. Migraine and cardiovascular disease: systematic review and meta-analysis. BMJ. 2009;339:b3914. DOI: 10.1136/bmj.b3914.</mixed-citation><mixed-citation xml:lang="en">Schurks M., Rist P.M., Bigal M.E., Buring J.E., Lipton R.B., Kurth T. Migraine and cardiovascular disease: systematic review and meta-analysis. BMJ. 2009;339:b3914. DOI: 10.1136/bmj.b3914.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Spector J.T., Kahn S.R., Jones M.R., Jayakumar M., Dalal D., Nazarian S. Migraine headache and ischemic stroke risk: an updated meta-analysis. Am. J. Med. 2010;123(7):612–624. DOI: 10.1016/j.amjmed.2009.12.021.</mixed-citation><mixed-citation xml:lang="en">Spector J.T., Kahn S.R., Jones M.R., Jayakumar M., Dalal D., Nazarian S. Migraine headache and ischemic stroke risk: an updated meta-analysis. Am. J. Med. 2010;123(7):612–624. DOI: 10.1016/j.amjmed.2009.12.021.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Дубенко О.Е., Гаврюшин А.Ю., Зубков А.В., Екимова С.В., Ковтунов О.В. Осложнения мигрени. Мигренозный инсульт: анализ клинических случаев. Международный неврологический журнал. 2020;16(6):60–66. DOI: 10.22141/2224-0713.16.6.2020.215142.</mixed-citation><mixed-citation xml:lang="en">Дубенко О.Е., Гаврюшин А.Ю., Зубков А.В., Екимова С.В., Ковтунов О.В. Осложнения мигрени. Мигренозный инсульт: анализ клинических случаев. Международный неврологический журнал. 2020;16(6):60–66. DOI: 10.22141/2224-0713.16.6.2020.215142.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Kruit M.C., van Buchem M.A., Launer L.J., Terwindt G.M., Ferrari M.D. Migraine is associated with an increased risk of deep white matter lesions, subclinical posterior circulation infarcts and brain iron accumulation: the population-based MRI camera study. Cephalalgia. 2010;30(2):129–136. DOI: 10.1111/j.1468-2982.2009.01904.x.</mixed-citation><mixed-citation xml:lang="en">Kruit M.C., van Buchem M.A., Launer L.J., Terwindt G.M., Ferrari M.D. Migraine is associated with an increased risk of deep white matter lesions, subclinical posterior circulation infarcts and brain iron accumulation: the population-based MRI camera study. Cephalalgia. 2010;30(2):129–136. DOI: 10.1111/j.1468-2982.2009.01904.x.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Tietjen G.E., Herial N.A., White L., Utley C., Kosmyna J.M., Khuder S.A. Migraine and biomarkers of endothelial activation in young women. Stroke. 2009;40(9):2977–2982. DOI: 10.1161/STROKEAHA.109.547901.</mixed-citation><mixed-citation xml:lang="en">Tietjen G.E., Herial N.A., White L., Utley C., Kosmyna J.M., Khuder S.A. Migraine and biomarkers of endothelial activation in young women. Stroke. 2009;40(9):2977–2982. DOI: 10.1161/STROKEAHA.109.547901.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Sarchielli P., Alberti A., Coppola F., Baldi A., Gallai B., Floridi A. et al. Platelet-activating factor (PAF) in internal jugular venous blood of migraine without aura patients assessed during migraine attacks. Cephalalgia. 2004;24(8):623–630. DOI: 10.1111/j.1468-2982.2003.00717.x.</mixed-citation><mixed-citation xml:lang="en">Sarchielli P., Alberti A., Coppola F., Baldi A., Gallai B., Floridi A. et al. Platelet-activating factor (PAF) in internal jugular venous blood of migraine without aura patients assessed during migraine attacks. Cephalalgia. 2004;24(8):623–630. DOI: 10.1111/j.1468-2982.2003.00717.x.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
