ssmuБюллетень сибирской медициныBulletin of Siberian Medicine1682-03631819-3684Siberian State Medical University, the Ministry of Healthcare of the Russian Federation10.20538/1682-0363-2012-4-49-56ssmu-538Research ArticleЭКСПЕРИМЕНТАЛЬНЫЕ И КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯEXPERIMENTAL AND CLINICAL INVESTIGATIONSФибриновые технологии в ускорении регенерации поврежденной кости в экспериментеThe fibrin technologies in acceleration of damaged bone regeneration in experimentМайбородин.И. В.MaiborodinI. V.imai@mail.ruШеплевБ. В.SheplevB. V.imai@mail.ruДровосековМ. Н.DrovosekovM. N.imai@mail.ruКолесниковИ. С.KolesnikovI. S.imai@mail.ruТодерМ. С.ToderM. S.imai@mail.ruШевелаА. А.ShevelaА. A.imai@mail.ruИнститут химической биологии и фундаментальной медицины СО РАН, г. НовосибирскRussian Federation2012280820121144956Copyright © Майбородин. И.В., Шеплев Б.В., Дровосеков М.Н., Колесников И.С., Тодер М.С., Шевела А.А., 20122012Майбородин. И.В., Шеплев Б.В., Дровосеков М.Н., Колесников И.С., Тодер М.С., Шевела А.А.Maiborodin I.V., Sheplev B.V., Drovosekov M.N., Kolesnikov I.S., Toder M.S., Shevela А.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://bulletin.ssmu.ru/jour/article/view/538

Морфологическими и радиовизиографическими методами изучали процессы регенерации поврежденного участка кости нижней челюсти крыс после заполнения дефекта костной ткани обогащенным тромбоцитами фибриновым сгустком. После операции с применением фибриновых технологий уже спустя 1 нед весь дефект костной ткани заполнен слившимися островками вновь сформированной кости. Ко 2-й нед отмечено дальнейшее замещение дефекта костной тканью и формирование костной мозоли.

The processes of regeneration of the damaged rat bottom jaw bone after application of enriched platelets a fibrin clot were studied by morphological and radiovisiographic methods. After operation with use of fibrin technologies already after 1 week the bone tissue defect is filled by the merged islets of again generated bone. By second week after fibrin use the further formation of bone tissue in defect and formation of a bone callosity is noted.

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The authors declare that there are no conflicts of interest present.