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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2024-1-134-143</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-5536</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Вульвовагинальная атрофия: современные методы диагностики и лечения (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Vulvovaginal atrophy: current methods of diagnosis and treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5256-843X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайнетдинова</surname><given-names>Л. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Zainetdinova</surname><given-names>L. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зайнетдинова Лариса Фоатовна – д-р мед. наук, доцент, профессор кафедры акушерства и гинекологии</p><p>454092, г. Челябинск, ул. Воровского, 64</p></bio><bio xml:lang="en"><p>64, Vorovskogo Str., Chelyabinsk, 454092</p></bio><email xlink:type="simple">sea-gull6@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7884-9675</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Телешева</surname><given-names>Л. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Telesheva</surname><given-names>L. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Телешева Лариса Федоровна –д-р мед. наук, профессор, профессор кафедры микробиологии, вирусологии, иммунологии</p><p>454092, г. Челябинск, ул. Воровского, 64</p></bio><bio xml:lang="en"><p>64, Vorovskogo Str., Chelyabinsk, 454092</p></bio><email xlink:type="simple">teleshevalarisa@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-5633-6951</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Медведев</surname><given-names>Б. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Medvedev</surname><given-names>B. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Медведев Борис Иванович –д-р мед. наук, профессор, профессор кафедры акушерства и гинекологии</p><p>454092, г. Челябинск, ул. Воровского, 64</p></bio><bio xml:lang="en"><p>64, Vorovskogo Str., Chelyabinsk, 454092</p></bio><email xlink:type="simple">borismedvedev423@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хахулина</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khakhulina</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хахулина Виктория Владимировна – преподаватель, кафедра акушерства и гинекологии</p><p>454092, г. Челябинск, ул. Воровского, 64</p></bio><bio xml:lang="en"><p>64, Vorovskogo Str., Chelyabinsk, 454092</p></bio><email xlink:type="simple">viktoriahahulina95@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Южно-Уральский государственный медицинский университет (ЮУГМУ)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>South Ural State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>11</day><month>04</month><year>2024</year></pub-date><volume>23</volume><issue>1</issue><fpage>134</fpage><lpage>143</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зайнетдинова Л.Ф., Телешева Л.Ф., Медведев Б.И., Хахулина В.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Зайнетдинова Л.Ф., Телешева Л.Ф., Медведев Б.И., Хахулина В.В.</copyright-holder><copyright-holder xml:lang="en">Zainetdinova L.F., Telesheva L.F., Medvedev B.I., Khakhulina V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/5536">https://bulletin.ssmu.ru/jour/article/view/5536</self-uri><abstract><p>Целью публикации является обзор современных методов диагностики и лечения вульво-вагинальной атрофии (ВВА), которая является одним из проявлений генитоуринарного менопаузального синдрома у женщин в перии постменопаузе.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Проведен обзор отечественных и зарубежных источников, посвященных распространенности, диагностике и методам лечения ВВА.</p></sec><sec><title>Результаты</title><p>Результаты. В отличие от вазомоторных симптомов, ВВА прогрессирует с возрастом, вызывая значительное нарушение качества жизни женщин. Симптомы, как правило, начинают беспокоить пациенток в перименопаузе, но их частота и выраженность значительно возрастают в постменопаузе. Диагностика ВВА может представлять некоторые трудности, так как многие женщины воспринимают свое состояние как естественное проявление старения организма и не обращаются за медицинской помощью. В настоящее время предложены медикаментозные и немедикаментозные методы лечения ВВА, каждый из которых имеет свои особенности, показания и противопоказания. Однако безопасность и эффективность некоторых из них полностью не доказана.</p></sec><sec><title>Заключение</title><p>Заключение. Вульво-вагинальная атрофия часто встречается у женщин перии постменопаузального возраста. Современные аспекты диагностики и лечения данной патологии позволяют значительно повысить качество жизни пациенток с симптомами ВВА, однако необходимы дальнейшие исследования для подтверждения безопасности предлагаемых методов лечения и поиск новых.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To review modern methods of diagnosis and treatment of vulvovaginal atrophy (VVA), which is one of the manifestations of genitourinary syndrome of menopause in periand postmenopausal women.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. A review of domestic and foreign literature on the prevalence and modern methods of diagnosis and treatment of VVA was carried out.</p></sec><sec><title>Results</title><p>Results. Unlike vasomotor symptoms, VVA progresses with age, causing a significant impairment in women’s quality of life. Symptoms usually begin to bother perimenopausal patients, but their frequency and severity increase significantly in postmenopausal women. Diagnosis of VVA can present some difficulties, as many women perceive their condition as a natural manifestation of aging and do not seek medical care. Currently, drug and non-drug therapies for VVA have been proposed, each of which has its own characteristics, indications, and contraindications. However, the safety and effectiveness of some of them have not been fully proven.</p></sec><sec><title>Conclusion</title><p>Conclusion. VVA is common in periand postmenopausal women. Modern aspects of the diagnosis and treatment of this pathology can significantly improve the quality of life of patients with VVA symptoms. However, further research is needed to confirm safety of the proposed treatment methods, and search for new techniques is required.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>вульво-вагинальная атрофия</kwd><kwd>генитоуринарный менопаузальный синдром</kwd><kwd>перии постменопауза</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vulvovaginal atrophy</kwd><kwd>genitourinary syndrome of menopause</kwd><kwd>periand postmenopause</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Юренева С.В., Ермакова Е.И., Глазунова А.В. Диагностика и терапия генитоуринарного менопаузального синдрома у пациенток в пери- и постменопаузе (краткие клинические рекомендации). Акушерство и гинекология. 2016;(5):138– 144. DOI: 10.18565/aig.2016.5.138-144.</mixed-citation><mixed-citation xml:lang="en">Юренева С.В., Ермакова Е.И., Глазунова А.В. 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