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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2024-2-190-198</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-5676</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ КЛИНИЧЕСКОЙ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Особенности течения муковисцидоза при сочетании Mycobacterium abscessus и Mycobacterium tuberculosis (клиническое наблюдение)</article-title><trans-title-group xml:lang="en"><trans-title>Features of cystic fibrosis development in a patient with coinfection by Mycobacterium abscessus and Mycobacterium tuberculosis (clinical case report)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5526-2513</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Филинюк</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Filinyuk</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Филинюк Ольга Владимировна – д-р мед. наук, профессор, зав. кафедрой фтизиатрии и пульмонологии </p><p>634050, г. Томск, Московский тракт, 2</p></bio><bio xml:lang="en"><p>2, Moscow Trakt, Tomsk, 634050</p></bio><email xlink:type="simple">filinyuk.olga@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-9782-351X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крук</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kruk</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Крук Евгений Александрович – главный врач </p><p>634050, г. Томск, ул. Розы Люксембург, 17</p></bio><bio xml:lang="en"><p>17, Rose Luxemburg Str., Tomsk, 634050</p></bio><email xlink:type="simple">rf200@list.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4323-2798</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тетенева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Teteneva</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тетенева Анна Валентиновна – д-р мед. наук, профессор, кафедра пропедевтики внутренних болезней с курсом терапии педиатрического факультета </p><p>634050, г. Томск, Московский тракт, 2;634063, г. Томск, ул. Бела Куна, 3</p></bio><bio xml:lang="en"><p>2, Moscow Trakt, Tomsk, 634050;3, Bela Kuna Str., Tomsk, 634063</p></bio><email xlink:type="simple">anna.dubodelova@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7483-7693</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Логинова</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Loginova</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Логинова Юлия Александровна – ассистент, кафедра фтизиатрии и пульмонологии </p><p>634050, г. Томск, Московский тракт, 2</p></bio><bio xml:lang="en"><p>2, Moscow Trakt, Tomsk, 634050</p></bio><email xlink:type="simple">julyaprk@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-8584-3666</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Костоякова</surname><given-names>Е. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kostoyakova</surname><given-names>E. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Костоякова Евгения Петровна – лаборант-исследователь, кафедра фтизиатрии и пульмонологии </p><p>634050, г. Томск, Московский тракт, 2</p></bio><bio xml:lang="en"><p>2, Moscow Trakt, Tomsk, 634050</p></bio><email xlink:type="simple">kostoyakova00@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4513-6329</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беспалова</surname><given-names>И. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Bespalova</surname><given-names>I. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Беспалова Инна Давидовна – д-р мед. наук, профессор, зав. кафедрой пропедевтики внутренних болезней с курсом терапии педиатрического факультета </p><p>634050, г. Томск, Московский тракт, 2</p></bio><bio xml:lang="en"><p>2, Moscow Trakt, Tomsk, 634050</p></bio><email xlink:type="simple">innadave@mail2000.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тетенев</surname><given-names>К. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Tetenev</surname><given-names>K. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тетенев Константин Федорович – канд. мед. наук, доцент, кафедра пропедевтики внутренних болезней с курсом терапии педиатрического факультета </p><p>634050, г. Томск, Московский тракт, 2</p></bio><bio xml:lang="en"><p>2, Moscow Trakt, Tomsk, 634050</p></bio><email xlink:type="simple">ktetenev@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3919-7205</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карзилов</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Karzilov</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Карзилов Александр Иванович – д-р мед. наук, профессор, кафедра пропедевтики внутренних болезней с курсом терапии педиатрического факультета </p><p>634050, г. Томск, Московский тракт, 2</p></bio><bio xml:lang="en"><p>2, Moscow Trakt, Tomsk, 634050</p></bio><email xlink:type="simple">karzilov.ai@ssmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2498-801X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мишустина</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Mishustina</surname><given-names>E. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мишустина Елена Львовна – канд. мед. наук, доцент, кафедра пропедевтики внутренних болезней с курсом терапии педиатрического факультета </p><p>634050, г. Томск, Московский тракт, 2</p></bio><bio xml:lang="en"><p>2, Moscow Trakt, Tomsk, 634050</p></bio><email xlink:type="simple">mishustina.el@ssmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Сибирский государственный медицинский университет (СибГМУ)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Siberian State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Томский фтизиопульмонологический медицинский центр (ТФМЦ)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tomsk Phthisiopulmonology Medical Cente</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Сибирский государственный медицинский университет (СибГМУ);&#13;
Медико-санитарная часть № 2</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Siberian State Medical University;&#13;
Primary Healthcare Unit No. 2</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>11</day><month>07</month><year>2024</year></pub-date><volume>23</volume><issue>2</issue><fpage>190</fpage><lpage>198</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Филинюк О.В., Крук Е.А., Тетенева А.В., Логинова Ю.А., Костоякова Е.П., Беспалова И.Д., Тетенев К.Ф., Карзилов А.И., Мишустина Е.Л., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Филинюк О.В., Крук Е.А., Тетенева А.В., Логинова Ю.А., Костоякова Е.П., Беспалова И.Д., Тетенев К.Ф., Карзилов А.И., Мишустина Е.Л.</copyright-holder><copyright-holder xml:lang="en">Filinyuk O.V., Kruk E.A., Teteneva A.V., Loginova Y.A., Kostoyakova E.P., Bespalova I.D., Tetenev K.F., Karzilov A.I., Mishustina E.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/5676">https://bulletin.ssmu.ru/jour/article/view/5676</self-uri><abstract><p>Представлено клиническое наблюдение, описывающее случай благоприятного клинического течения микобактериоза и туберкулеза легких, вызванных микст-инфекцией M. аbscessus и M. tuberculosis у пациентки с легочными проявлениями кистозного фиброза (муковисцидоза) через 1 год после родоразрешения. Данный результат лечения был достигнут с помощью своевременной диагностики, начатому лечению туберкулеза и микобактериоза легких у пациентки с кистозным фиброзом (муковисцидозом). Благодаря развитию в Томской области микробиологической видовой идентификации микобактерий, был верифицирован микобактериоз легких, что еще в недавнем прошлом было проблематично, и все случаи с положительной микроскопией были отнесены к туберкулезу.</p></abstract><trans-abstract xml:lang="en"><p>The article presents a clinical case describing a favorable clinical outcome of mycobacterial infection and pulmonary tuberculosis caused by coinfection of M. abscessus and M. tuberculosis in a patient with pulmonary manifestations of cystic fibrosis one year after delivery. This outcome was achieved due to timely diagnosis and treatment of pulmonary tuberculosis and non-tuberculous mycobacterial infection in the patient with cystic fibrosis. Due to the development of molecular identification of mycobacteria species in the Tomsk region, mycobacterial lung disease was verified, which was challenging in the recent past. Previously, all cases with microscopic examination results positive for mycobacteria were classified as tuberculosis. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>кистозный фиброз (муковисцидоз)</kwd><kwd>нетуберкулезные микобактерии</kwd><kwd>M. abscessus</kwd><kwd>туберкулез легких</kwd><kwd>M. tuberculosis</kwd><kwd>микст-инфекция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cystic fibrosis</kwd><kwd>nontuberculous mycobacteria</kwd><kwd>M. abscessus</kwd><kwd>pulmonary tuberculosis</kwd><kwd>M. tuberculosis</kwd><kwd>coinfection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Moore M., Frerichs J.B. 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