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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2026-2-21-31</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-6523</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL PAPERS</subject></subj-group></article-categories><title-group><article-title>Математическое моделирование структуры внутрипочечного артериального русла с помощью регрессионных моделей и графовой нейронной сети</article-title><trans-title-group xml:lang="en"><trans-title>Mathematical modeling of the intrarenal arterial bed structure using regression models and a graph neural network</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5447-1989</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зенин</surname><given-names>О. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Zenin</surname><given-names>O. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зенин Олег Константинович – д-р мед. наук, профессор, профессор кафедры «Анатомия человека»</p><p>Россия, 440026, г. Пенза, ул. Красная, 40</p></bio><bio xml:lang="en"><p> 40 Krasnaya St., 440026 Penza, Russian Federation </p></bio><email xlink:type="simple">zen.olegz@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1012-8855</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горбаченко</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorbachenko</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Горбаченко Владимир Иванович – д-р тех. наук, профессор, зав. кафедрой «Компьютерные технологии» </p><p>Россия, 440026, г. Пенза, ул. Красная, 40</p></bio><bio xml:lang="en"><p> 40 Krasnaya St., 440026 Penza, Russian Federation </p></bio><email xlink:type="simple">gorvi@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4728-5923</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Грибков</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Gribkov</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Грибков Дмитрий Николаевич – аспирант, кафедра «Компьютерные технологии»</p><p>Россия, 440026, г. Пенза, ул. Красная, 40</p></bio><bio xml:lang="en"><p> 40 Krasnaya St., 440026 Penza, Russian Federation </p></bio><email xlink:type="simple">rororol23@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-1380-8767</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергиенко</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sergienko</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергиенко Анна Альбертовна – аспирант, кафедра «Анатомия человека»</p><p>Россия, 440026, г. Пенза, ул. Красная, 40</p></bio><bio xml:lang="en"><p>40 Krasnaya St., 440026 Penza, Russian Federation</p></bio><email xlink:type="simple">anya.gurieva00@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9130-3255</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Miltiadis</surname><given-names>Ilias</given-names></name><name name-style="western" xml:lang="en"><surname>Miltiadis</surname><given-names>Ilias</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ilias Miltiadis – магистрант</p><p>Италия, 90133, г. Палермо, ул. Пиацца Марина, 61</p></bio><bio xml:lang="en"><p>61 Piazza Marina St., 90133 Palermo, Italy</p></bio><email xlink:type="simple">contact@miltykh.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Пензенский государственный университет (ПГУ)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Penza State University (PSU)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Университет Палермо</institution><country>Италия</country></aff><aff xml:lang="en"><institution>The University of Palermo</institution><country>Italy</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>23</day><month>07</month><year>2026</year></pub-date><volume>25</volume><issue>2</issue><fpage>21</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зенин О.К., Горбаченко В.И., Грибков Д.Н., Сергиенко А.А., Miltiadis I., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Зенин О.К., Горбаченко В.И., Грибков Д.Н., Сергиенко А.А., Miltiadis I.</copyright-holder><copyright-holder xml:lang="en">Zenin O.K., Gorbachenko V.I., Gribkov D.N., Sergienko A.A., Miltiadis I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/6523">https://bulletin.ssmu.ru/jour/article/view/6523</self-uri><abstract><p>Цель – разработать модели для численного моделирования диаметров и длин сегментов бифуркаций – структурных единиц внутрипочечного артериального русла (ВАР).Материалы и методы. Исследование основано на ранее полученных морфометрических данных о структуре 9 642 артериальных бифуркаций (АБ) 60 коррозионных препаратов ВАР. Артериальная бифуркация – участок ВАР, состоящий из проксимального артериального сегмента (АС) (D), двух дистальных АС (с большей (dmax) и меньшей (dmin) величиной внутреннего диаметра) и точки ветвления. Для численного моделирования диаметров (АС) использовали регрессионные модели, для моделирования длин АС – графовую нейронную сеть внимания (GAT).Результаты. Разработаны модели, которые демонстрируют высокую точность прогнозирования: для диаметров АС с dmax обучающий набор достиг значения R2 = 0,89, для АС с dmin – R2 = 0,8. Для длины АС с dmax обучающий набор достигал значения R2 = 0,75, а тестовый набор – R2 = 0,74; для длины АС с dmin обучающий набор достиг значения R2 = 0,77, а тестовый набор – R2 = 0,73.Заключение. Предложенные модели могут быть использованы для численного моделирования структуры ВАР и оценки адекватности почечного кровоснабжения.</p></abstract><trans-abstract xml:lang="en"><p>The aim was to develop models for numerical modeling of the diameters and lengths of bifurcation segments, structural units of the intrarenal arterial bed (IAB).Materials and methods. The study is based on previously obtained morphometric data on the structure of 9,642 arterial bifurcations (AB) of 60 corrosion casts of the IAB. AB is a section of the IAB consisting of a proximal arterial segment (AS) (D), two distal AS (with a larger (dmax) and smaller (dmin) internal diameter) and a branching point. Regression models were used for numerical modeling of the AS diameters, while a graph attention network (GAT) was used for the lengths of AS.Results. The developed models demonstrate high prediction accuracy: for AS diameters with a larger value (dmax), the training set reached an R2 value of 0.89, for AS with a smaller value (dmin) – R2 = 0.8. For the length of the AS with a larger diameter, the training set reached an R2 value of 0.75, and the test set reached an R2 value of 0.74; for the length of the AS with a smaller diameter, the training set reached an R2 value of 0.77, and the test set reached an R2 value of 0.73.Conclusion. The proposed models can be used for numerical modeling of the IAB structure and assessment of the adequacy of renal blood supply.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>внутрипочечное артериальное русло</kwd><kwd>артериальная бифуркация</kwd><kwd>численное моделирование</kwd><kwd>нейронные сети</kwd></kwd-group><kwd-group xml:lang="en"><kwd>intrarenal arterial bed</kwd><kwd>arterial bifurcation</kwd><kwd>numerical modeling</kwd><kwd>neural networks</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Borg R., Carlson N., Søndergaard J., Persson F. The growing challenge of chronic kidney disease: an overview of current knowledge. Int. J. Nephrol. 2023:9609266. DOI: 10.1155/2023/9609266.</mixed-citation><mixed-citation xml:lang="en">Borg R., Carlson N., Søndergaard J., Persson F. The growing challenge of chronic kidney disease: an overview of current knowledge. Int. 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