<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ssmu</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень сибирской медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Siberian Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-0363</issn><issn pub-type="epub">1819-3684</issn><publisher><publisher-name>Siberian State Medical University, the Ministry of Healthcare of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20538/1682-0363-2017-2-71-86</article-id><article-id custom-type="elpub" pub-id-type="custom">ssmu-877</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL PAPERS</subject></subj-group></article-categories><title-group><article-title>Психологические дисфункции у женщин с бронхиальной астмой</article-title><trans-title-group xml:lang="en"><trans-title>Psychological dysfunctions in women with bronchial asthma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Астафьева</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Astafieva</surname><given-names>Natalia G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, профессор, зав. кафедрой клинической иммунологии и аллергологии</p><p>410012, г. Саратов, ул. Большая Казачья, 112 </p></bio><bio xml:lang="en"><p>DM, Professor, Head of the Department of Clinical Immunology and Allergology</p><p>112, Bol’shaya Kazach’ya Str., Saratov, 410012</p></bio><email xlink:type="simple">astang@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кобзев</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kobzev</surname><given-names>Denis Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, профессор, директор бизнес-образования, школа здравоохранения и социальных наук</p><p>LS18 5HD, Браунберри линия, Хорсфорт </p></bio><bio xml:lang="en"><p>PhD, Professor, Director of Business Education, School of Health and Social Sciences</p><p>Brownberrie Ln., Leeds LS18 5HD, UK</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стрилец</surname><given-names>Г. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Strilets</surname><given-names>Galina N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант кафедры клинической иммунологии и аллергологии</p><p>410012, г. Саратов, ул. Большая Казачья, 112 </p></bio><bio xml:lang="en"><p>Postgraduate Student of the Department of Clinical Immunology and Allergology</p><p>112, Bol’shaya Kazach’ya Str., Saratov, 410012</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гамова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gamova</surname><given-names>Inna V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, доцент кафедры клинической иммунологии и аллергологии</p><p>410012, г. Саратов, ул. Большая Казачья, 112 </p></bio><bio xml:lang="en"><p>PhD, Associate Professor of the Department of Clinical Immunology and Allergology</p><p>112, Bol’shaya Kazach’ya Str., Saratov, 410012</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Перфилова</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Perfilova</surname><given-names>Irina A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, ассистент кафедры клинической иммунологии и аллергологии</p><p>410012, г. Саратов, ул. Большая Казачья, 112 </p></bio><bio xml:lang="en"><p>PhD, Assistant of the Department of Clinical Immunology and Allergology</p><p>112, Bol’shaya Kazach’ya Str., Saratov, 410012</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Удовиченко</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Udovichenko</surname><given-names>Ekaterina N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, ассистент кафедры клинической иммунологии и аллергологии</p><p>410012, г. Саратов, ул. Большая Казачья, 112 </p></bio><bio xml:lang="en"><p>Assistant of the Department of Clinical Immunology and Allergology</p><p>112, Bol’shaya Kazach’ya Str., Saratov, 410012</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Саратовский государственный медицинский университет (ГМУ) имени В. И. Разумовского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saratov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Лидс Тринити университет, г. Лидс</institution><country>Великобритания</country></aff><aff xml:lang="en"><institution>Leeds Trinity University</institution><country>United Kingdom</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>12</day><month>07</month><year>2017</year></pub-date><volume>16</volume><issue>2</issue><fpage>71</fpage><lpage>86</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Астафьева Н.Г., Кобзев Д.Ю., Стрилец Г.Н., Гамова И.В., Перфилова И.А., Удовиченко Е.Н., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Астафьева Н.Г., Кобзев Д.Ю., Стрилец Г.Н., Гамова И.В., Перфилова И.А., Удовиченко Е.Н.</copyright-holder><copyright-holder xml:lang="en">Astafieva N.G., Kobzev D.Y., Strilets G.N., Gamova I.V., Perfilova I.A., Udovichenko E.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://bulletin.ssmu.ru/jour/article/view/877">https://bulletin.ssmu.ru/jour/article/view/877</self-uri><abstract><sec><title>Введение</title><p>Введение. Важность психосоциальных факторов в управлении бронхиальной астмой (БА) обсуждается в клинических руководствах, включая международные и национальные клинические рекомендации, однако требуется конкретная оценка их роли в качестве причин плохого контроля астмы в уязвимых группах пациентов.</p></sec><sec><title>Цель исследования</title><p>Цель исследования. Оценка психологического здоровья женщин с разным уровнем контроля бронхиальной астмы.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В исследование включены 108 женщин с бронхиальной астмой, наблюдающихся в Саратовском аллергологическом центре, которые были стратифицированы на три группы в соответствии с уровнем контроля (хороший, частичный, неконтролируемый (GINA)). При постановке диагноза бронхиальной астмы использованы стандартные методы (анамнез, симптомы, спирография). Для оценки уровня контроля использовались Asthma Control Questionnaire 5 items-self-administered (ACQ-5), качества жизни – опросники Asthma Quality of Life Questionnaire S (AQLQ-S), 36-ltem MOS Short-Form Health Survey (SF-36), стандартизированная и валидизированная русскоязычная версия опросника женского здоровья Women’s Health Questionnaire (WHQ). Для психологической диагностики и оценки социально-личностных компетенций, способствующих сохранению и развитию здоровья человека (интеллектуальный, личностный, эмоциональный, физический, социальный, творческий, духовный аспекты), применялся мультимодальный интегрированный опросник (МИО). Сравнение проводилось с контрольной группой мужчин с бронхиальной астмой, сопоставимых по возрасту и уровню контроля.</p></sec><sec><title>Результаты</title><p>Результаты. Женщины с плохо контролируемой астмой имели худшие показатели AQLQ-S (суммарная медиана баллов 3,43 вместо 5,13 в группе хорошего контроля; p &lt; 0,05); всех шкал SF-36, включая общее состояние (43,48 против 55,07), роль физических (25,93 против 57,76) и эмоциональных проблем (43,83 против 64,37); р &lt; 0,05. По опроснику WHQ (обратная зависимость: чем выше балл, тем ниже качество жизни) при плохом контроле отмечается высокая выраженность депрессии (среднее значение 0,36 против 0,24; p &lt; 0,05), проблем физического здоровья (0,47 против 0,27; p &lt; 0,05). Отмечена чрезвычайно низкая оценка собственной привлекательности при БА (0,71 и 0,64 соответственно при плохом и хорошем контроле). По опроснику МИО у мужчин и женщин с БА получены практически одинаковые показатели по шкалам, чувствительным к проявлениям тревожно-депрессивной симптоматики, эмоциональной уравновешенности, шкалам эмотивных навыков, коррелирующих с выраженной алекситимией и низкой способностью к рефлексии. Среди женщин была выше доля индивидуумов с высокими шкалами интеллектуального функционирования, волевой компетенции, целеполагания, контактности.</p></sec><sec><title>Заключение</title><p>Заключение. Тяжесть астмы, контроль заболевания тесно связаны с психологическим состоянием больного. Существует необходимость в междисциплинарном подходе, направленном на выявление и эффективную коррекцию психофункциональных расстройств при БА. Изучение психологических особенностей личности и мотивационной сферы пациента может способствовать оптимизации терапии, улучшению контроля и прогноза заболевания. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. The importance of psychosocial factors in the management of bronchial asthma (BA) is discussed in clinical guidelines, including in international and national clinical guidelines. However, a specific evaluation of their role as a cause of poor asthma control in susceptible patients is required. Aim. Assessment of psychological health of women with different levels of asthma control.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study included 108 women with asthma observed in Saratov center for Allergology who were stratified into 3 groups according to the control level (good, partial, uncontrolled, according to GINA). In establishing a diagnosis of asthma, standard methods were used (medical history, symptoms, spirography). To assess the level of control, ACQ-5 (Asthma Control Questionnaire 5 items-self-administered) was used, to assess the quality of life, questionnaires AQLQ-S (Asthma Quality of Life Questionnaire S); SF-36 (36-ltem MOS Short-Form Health Survey), a standardized and validated Russian version of the women’s health questionnaire WHQ (Women’s Health Questionnaire) were used; for psychological diagnosis and evaluation of social and personal competencies that contribute to the preservation and improvement of human health (the intellectual, personal, emotional, physical, social, creative, spiritual aspects), integrated multimodal questionnaire was used. The comparison was conducted with a control group of men with bronchial asthma, comparable in age and level of control.</p></sec><sec><title>Results</title><p>Results. Women with poorly controlled asthma had worse performance of AQLQ-S (combined median score of 3,43 instead of 5,13 in the group of good control; p &lt; 0,05); all scales of the SF-36, including the general condition (43,48 against 55,07), role of physical (25,93 against 57,76) and emotional problems (43,83 against 64,37); at p &lt; 0.05. According to the WHQ questionnaire (the inverse relationship: the higher the score, the lower the quality of life) in the group with poor control there is a high level of depression (mean 0,36 versus 0,24; p &lt; 0,05); physical health problems are marked (0,47 against 0,27; p &lt; 0,05). There is a very low selfestimation of their attractiveness in BA (0,71 and 0,64 for bad and good control, respectively). According to the integrated multimodal questionnaire, in both men and women with asthma almost identical results were obtained on the scales sensitive to manifestations of anxiety-depressive symptoms, emotional balance, scales of emotional skills, correlating with severe alexithymia and low capacity for reflection. Among women the proportion of individuals with high scores of intellectual functioning, strong-willed competence, goal-setting, and ability of making contacts was higher.</p></sec><sec><title>Conclusion</title><p>Conclusion. The severity of asthma and disease control are closely linked with the psychological condition of the patient. Psychological dysfunctions are correlated with suboptimal BA control. It is important to understand psychological differences in women and to educate patients in both effective BA control and in establishing individualized asthma management strategies.There is a need for a multidisciplinary approach aimed at the identification and effective correction of asthma. The study of the psychological characteristics of personality and motivational sphere of the patient can help to optimize therapy, improve monitoring and prognosis of the disease. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>контроль астмы</kwd><kwd>половые различия</kwd><kwd>качество жизни</kwd><kwd>психологические дисфункции</kwd><kwd>астма у женщин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>asthma control</kwd><kwd>sex differences</kwd><kwd>quality of life</kwd><kwd>psychological dysfunction</kwd><kwd>asthma in women</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Авторы выражают признательность доценту кафедры «Технологии программирования» Саратовского Национального исследовательского государственного университета им. Н.Г. Чернышевского, канд. физ.-мат. наук Г.Г. Наркайтису за помощь при проведении статистического анализа данных.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Global Strategy for asthma management and prevention [Electronic resource] // Global Initiative for Asthma. GINA. URL: http: // www.slideshare.net/cristobalbunuel/gina-report-2016; 2016. Vol. 2016. URL: http: // www.ginasthma.org/local / uploads/files/GINA_Report_ 2016.pdf.</mixed-citation><mixed-citation xml:lang="en">Global Strategy for asthma management and prevention [Electronic resource] // Global Initiative for Asthma. GINA. URL: http: // www.slideshare.net/cristobalbunuel/ gina-report-2016; 2016. Vol. 2016. URL: http: // www.ginasthma.org/local / uploads/files/GINA_Report_2016.pdf.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Федеральные клинические рекомендации по бронхиальной астме. 2016: 64 http://spulmo.ru/obshchestvo/ news/news-812/.</mixed-citation><mixed-citation xml:lang="en">Federal’nye klinicheskie rekomendacii po bronhial’noi astme [Federal guidelines for the bronchial asthma] 2016: 64. http://spulmo.ru/obshchestvo/news/news-812/ (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Национальная программа «Бронхиальная астма у детей. Стратегия лечения и профилактика». 4-е изд., пе- рераб. и доп. М.: Medical, 2012: 182.</mixed-citation><mixed-citation xml:lang="en">Nacional’naya programma «Bronhial’naya astma u detei. Strategiya lecheniya i profilaktika» [National program “Bronchial asthma in children. Treatment and prevention strategies”] 4th ed., rev. and ext. Medical Publ., 2012: 182 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Глобальная стратегия профилактики и лечения бронхиальной астмы GINA. Global strategy for asthma management and prevention, 2014 Available at: http://www.ginasthma.org/uploads/users/files/GINA_Report_2014.pdf.</mixed-citation><mixed-citation xml:lang="en">Global strategy for asthma management and prevention, 2014 Available at: http://www.ginasthma.org/uploads/users/files/GINA_Report_2014.pdf;/ Global’naya strategiya profilaktiki i lecheniya Bronhial’noi astmy (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Braido F., Brusselle G., Guastalla D., Ingrassia E., Nicolini G., Price D., Roche N., Soriano J.B., Worth H.; LIAISON Study Group. Determinants and impact of suboptimal asthma control in Europe: The INTERNATIONAL CROSS-SECTIONAL AND LONGITUDINAL ASSESSMENT ON ASTHMA CONTROL (LIAISON) study // Respir Res. 2016; May, 14, 17 (1): 51. doi: 10.1186/s12931- 016-0374.</mixed-citation><mixed-citation xml:lang="en">Braido F., Brusselle G., Guastalla D., Ingrassia E., Nicolini G., Price D., Roche N., Soriano J.B., Worth H.; LIAISON Study Group. Determinants and impact of suboptimal asthma control in Europe: The INTERNATIONAL CROSS-SECTIONAL AND LONGITUDINAL ASSESSMENT ON ASTHMA CONTROL (LIAISON) study // Respir Res. 2016; May, 14, 17 (1): 51. doi: 10.1186/s12931- 016-0374.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Nathan R.A., Thompson P.J., Price D., Fabbri L.M., Salvi S., González-Díaz S., Maspero J.F., Moreno-Cantu J.J., Fish J.E., Murphy K. Taking aim at asthma around the world: global results of the asthma insight and management survey in the Asia-Pacific Region, Latin America, Europe, Canada and the United States // J. Allergy Clin. Immunol. Pract. 2015; Sep.–Oct., 3 (5): 734–742. e5. doi: 10.1016/j.jaip.2015.04.013. Epub 2015 Jun. 23.</mixed-citation><mixed-citation xml:lang="en">Nathan R.A., Thompson P.J., Price D., Fabbri L.M., Salvi S., González-Díaz S., Maspero J.F., Moreno-Cantu J.J., Fish J.E., Murphy K. Taking aim at asthma around the world: global results of the asthma insight and management survey in the Asia-Pacific Region, Latin America, Europe, Canada and the United States // J. Allergy Clin. Immunol. Pract. 2015; Sep.–Oct., 3 (5): 734–742. e5. doi: 10.1016/j.jaip.2015.04.013. Epub 2015 Jun 23.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Архипов В.В., Григорьева Е.В., Гавришина Е.В. Контроль над бронхиальной астмой в России: результа- ты многоцентрового наблюдательного исследования НИКА // Пульмонология. 2011; 6: 87–93.</mixed-citation><mixed-citation xml:lang="en">Arkhipov V.V., Grigor’eva E.V., Gavrishina E.V. Kontrol’ nad bronhial’noi astmoi v Rossii: rezul’taty mnogocentrovogo nablyudatel’nogo issledovaniya NIKA [Asthma control in Russia: results of the multicenter observational study NIKA] // Pulmonology. 2011; 6: 87–93 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Wenzel S. Asthma: defining of the persistent adult phenotypes // Lancet. 2006; 368: 804–813.</mixed-citation><mixed-citation xml:lang="en">Wenzel S. Asthma: defining of the persistent adult phenotypes // Lancet. 2006; 368: 804–813.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Lötvall J., Akdis C.A., Bacharier L.B. et al. Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome // The Journal of Allergy and Clinical Immunology. 2011; 127 (2): 355–360.</mixed-citation><mixed-citation xml:lang="en">Lötvall J., Akdis C.A., Bacharier L.B. et al. Asthma endotypes: A new approach to classification of disease entities within the asthma syndrome // The Journal of Allergy and Clinical Immunology. 2011; 127 (2): 355–360.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Haldar Р., Pavord I.D, Shaw D.E. et al. Cluster аnalysis and сlinical ааsthma рhenotypes // AJRCCM. 2008; 178: 218–224.</mixed-citation><mixed-citation xml:lang="en">Haldar Р., Pavord I.D, Shaw D.E. et al. Cluster аnalysis and сlinical ааsthma рhenotypes // AJRCCM. 2008; 178: 218–224.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Agache I., Akdis C., Jutel M. et al. Untangling asthma phenotypes and endotypes // Allergy. 2012; 67: 835–846.</mixed-citation><mixed-citation xml:lang="en">Agache I., Akdis C., Jutel M. et al. Untangling asthma phenotypes and endotypes // Allergy. 2012; 67: 835–846.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин А.Г. Новые перспективы в терапии бронхиальной астмы // Пульмонология. 2011; (4): 5–12.</mixed-citation><mixed-citation xml:lang="en">Chuchalin A.G. Novye perspektivy v terapii bronhial’noi astmy [New perspectives in the treatment of asthma] // Pul’monologiya – Pul’monology. 2011; (4): 5–12 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Muraro A., Lemanske R.F. Jr., Castells M., Torres M.J., Khan D., Simon H.U., Bindslev-Jensen C., Burks W., Poulsen L.K., Sampson H.A., Worm M., Nadeau K.C. Precision Medicine in Allergic Disease – Food Allergy, Drug Allergy, and Anaphylaxis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma &amp; Immunology // Allergy. 2017; Jan., 25. doi: 10.1111/ all.13132. [Epub ahead of print].</mixed-citation><mixed-citation xml:lang="en">Muraro A., Lemanske R.F. Jr., Castells M., Torres M.J., Khan D., Simon H.U., Bindslev-Jensen C., Burks W., Poulsen L.K., Sampson H.A., Worm M., Nadeau K.C. Precision Medicine in Allergic Disease – Food Allergy, Drug Allergy, and Anaphylaxis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma &amp; Immunology // Allergy. 2017; Jan., 25. doi: 10.1111/ all.13132. [Epub ahead of print].</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Kynyk J.A., Mastronarde J.G., McCallister J.W. Asthma, the sex difference // Curr. Opin. Pulm. Med. 2011; Jan, 17 (1): 6–11. doi: 10.1097/MCP.0b013e3283410038.</mixed-citation><mixed-citation xml:lang="en">Kynyk J.A., Mastronarde J.G., McCallister J.W. Asthma, the sex difference // Curr. Opin. Pulm. Med. 2011; Jan., 17 (1): 6–11. doi: 10.1097/MCP.0b013e3283410038.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Zein J.G.., Erzurum S.C. Asthma is different in women // Curr. Allergy Asthma Rep. 2015; Jan., 15 (6): 28. doi: 10.1007/s11882-015-0528-y.</mixed-citation><mixed-citation xml:lang="en">Zein J.G.., Erzurum S.C. Asthma is different in women // Curr. Allergy Asthma Rep. 2015; Jan., 15 (6): 28. doi: 10.1007/s11882-015-0528-y.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Laidlaw T.M., Boyce J.A. Aspirin-exacerbated respiratory disease – new prime suspects // N. Engl J. Med. 2016; 4: 484–488.</mixed-citation><mixed-citation xml:lang="en">Laidlaw T.M., Boyce J.A. Aspirin-exacerbated respiratory disease – new prime suspects // N. Engl J. Med. 2016; 4: 484–488.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Kowalski M.L., Makowska J.S., Blanca M. et al. Hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) – classification, diagnosis and management: review of the EAACI/ENDA and GA2LEN/ HANNA // Allergy. 2011; 66: 818–829.</mixed-citation><mixed-citation xml:lang="en">Kowalski M.L., Makowska J.S., Blanca M. et al. Hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) – classification, diagnosis and management: review of the EAACI/ENDA and GA2LEN/ HANNA // Allergy. 2011; 66: 818–829.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Rajan J.P., Wineinger N.E., Stevenson D.D. et al. Prevalence of aspirin-exacerbated respiratory disease among asthmatic patients: a meta-analysis of the literature // J. Allergy Clin. Immunol. 2015; 135: 676–681.</mixed-citation><mixed-citation xml:lang="en">Rajan J.P., Wineinger N.E., Stevenson D.D. et al. Prevalence of aspirin-exacerbated respiratory disease among asthmatic patients: a meta-analysis of the literature // J. Allergy Clin. Immunol. 2015; 135: 676–681.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Morales D.R., Guthrie B., Lipworth B.J. et al. NSAID-exacerbated respiratory disease: a meta-analysis evaluating prevalence, mean provocative dose of aspirin and increased asthma morbidity // Allergy. 2015; 70: 828–835.</mixed-citation><mixed-citation xml:lang="en">Morales D.R., Guthrie B., Lipworth B.J. et al. NSAID-exacerbated respiratory disease: a meta-analysis evaluating prevalence, mean provocative dose of aspirin and increased asthma morbidity // Allergy. 2015; 70: 828– 835.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Skloot G. S. Asthma phenotypes and endotypes: a personalized approach to treatment // Curr. Opin. Pulm. Med. 2016; 22: 3–9.</mixed-citation><mixed-citation xml:lang="en">Skloot G. S. Asthma phenotypes and endotypes: a personalized approach to treatment // Curr. Opin. Pulm. Med. 2016; 22: 3–9.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Kowalski M.L., Bavbek S. Aspirin exacerbated respiratory disease. Global Atlas of Asthma; ed. Akdis C.A., Agache I. EAACI, 2013: 92–94.</mixed-citation><mixed-citation xml:lang="en">Kowalski M.L., Bavbek S. Aspirin exacerbated respiratory disease. Global Atlas of Asthma; ed. Akdis C.A., Agache I. EAACI, 2013: 92–94.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">European Network for Understanding Mechanisms of Severe Asthma. The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma // Eur. Respir. J. 2003; 22 (3): 470–477. [PubMed: 14516137].</mixed-citation><mixed-citation xml:lang="en">European Network for Understanding Mechanisms of Severe Asthma. The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma // Eur. Respir. J. 2003; 22 (3): 470–477. [PubMed: 14516137].</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Leynaert B. et al. Gender differences in prevalence, diagnosis and incidence of allergic and non-allergic asthma: a population-based cohort // Thorax. 2012; 67 (7): 625–631. [PubMed: 22334535].</mixed-citation><mixed-citation xml:lang="en">Leynaert B. et al. Gender differences in prevalence, diagnosis and incidence of allergic and non-allergic asthma: a population-based cohort // Thorax. 2012; 67 (7): 625–631. [PubMed: 22334535].</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Jain R. et al. Sex hormone-dependent regulation of cilia beat frequency in airway epithelium // Am. J. Respir. Cell Mol. Biol. 2012; 46 (4): 446–453. [PubMed: 22033264]. 26. Lisspers K. et al. Sex-differences in quality of life and asthma control in Swedish asthma patients // J. Asthma. 2013; 50 (10): 1090–1095.</mixed-citation><mixed-citation xml:lang="en">Jain R. et al. Sex hormone-dependent regulation of cilia beat frequency in airway epithelium // Am. J. Respir. Cell Mol. Biol. 2012; 46. (4): 446–453. [PubMed: 22033264].</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Астафьева Н.Г., Гамова И. В., Удовиченко Е.Н., Пер- филова И.А., Наумова О.С. Фенотип астмы с ожире- нием : клинические особенности, диагностика, лече- ние // Астма и аллергия. 2015; 1 (72): 3–12.</mixed-citation><mixed-citation xml:lang="en">Lisspers K. et al. Sex-differences in quality of life and asthma control in Swedish asthma patients // J. Asthma. 2013; 50 (10): 1090–1095.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Hirose M., Kondo R., Ban N., Kuwabara K., Shiga M., Horiguchi T.. Sex differences in use of inhalants by elderly patients with asthma // Clin. Interv. Aging. 2015; Aug., 10, 10: 1305–1310. doi: 10.2147/CIA.S84271.</mixed-citation><mixed-citation xml:lang="en">Astaf’eva N.G. , Gamova I. V., Udovichenko E.N., Perfilova I.A., Naumova O.S. Fenotip astmy s ozhireniem: klinicheskie osobennosti, diagnostika, lechenie [The phenotype of asthma with obesity: clinical features, diagnosis and treatment] // Astma i allergiya – Asthma and Allergy. 2015; 1 (72): 3–12 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">McCallister J.W. et al. Sex differences in asthma symptom profiles and control in the American Lung Association Asthma Clinical Research Centers // Respir. Med. 2013; 107 (10): 1491–1500.</mixed-citation><mixed-citation xml:lang="en">Hirose M., Kondo R., Ban N., Kuwabara K., Shiga M., Horiguchi T.. Sex differences in use of inhalants by elderly patients with asthma // Clin. Interv. Aging. 2015; Aug., 10, 10: 1305–1310. doi: 10.2147/CIA.S84271.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Panek M., Pietras T., Witusik A., Wieteska Ł., Małachowska B., Mokros Ł., Fendler W., Szemraj J., Kuna P. Identification and association of relationships between selected personal and environmental factors and formal components of temperament and strategies of coping with stress in asthmatic patients // Physiol. Behav. 2015; Oct., 1, 149: 269–278. doi: 10.1016/j.physbeh.2015.06.023. Epub 2015 Jun. 14.</mixed-citation><mixed-citation xml:lang="en">McCallister J.W. et al. Sex differences in asthma symptom profiles and control in the American Lung Association Asthma Clinical Research Centers // Respir. Med. 2013; 107 (10): 1491–1500.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Овчаренко С.И., Смулевич А.Б., Акулова М.Н. Контроль течения БА: психосоматические соотношения и расстройства личности // Практ. пульмонология. 2009; 1: 22–25.</mixed-citation><mixed-citation xml:lang="en">Panek M., Pietras T., Witusik A., Wieteska Ł., Małachowska B., Mokros Ł., Fendler W., Szemraj J., Kuna P. Identification and association of relationships between selected personal and environmental factors and formal components of temperament and strategies of coping with stress in asthmatic patients // Physiol. Behav. 2015; Oct., 1; 149: 269–278. doi: 10.1016/j.physbeh.2015.06.023. Epub 2015 Jun 14.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Amore M., Antonucci C., Bettini E. et al. Disease control in patients with asthma is associated with alexithymia but not with depression or anxiety // Behav. Med. 2013; 39 (4): 138–145.</mixed-citation><mixed-citation xml:lang="en">Ovcharenko S.I., Smulevich A.B., Akulova M.N. Kontrol’ techeniia BA: psikhosomaticheskie sootnosheniia i rasstroistva lichnosti [Control of asthma: psychosomatic relations and personality disorders] // Prakt. pul’monologiia – Pract. pulmonology. 2009 1: 22–25 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Loerbroks A., Li J., Bosch J.A., Herr R.M., Angerer P. Personality and risk of adult asthma in a prospective cohort study // J. Psychosom. Res. 2015; Jul., 79 (1): 13–17. doi: 10.1016/j.jpsychores.2015.04.002. Epub 2015; Apr. 11.</mixed-citation><mixed-citation xml:lang="en">Amore M., Antonucci C., Bettini E. et al. Disease control in patients with asthma is associated with alexithymia but not with depression or anxiety // Behav. Med. 2013; 39 (4): 138–145.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Loerbroks A., Apfelbacher C.J., Thayer J.F., Debling D., Stürmer T. Neuroticism, extraversion, stressful life events and asthma: a cohort study of middle-aged adults // Allergy. 2009; Oct., 64 (10): 1444–1450. doi: 10.1111/j.1398- 9995.2009.02019.x. Epub 2009 Feb. 25.</mixed-citation><mixed-citation xml:lang="en">Loerbroks A., Li J., Bosch J.A., Herr R.M., Angerer P. Personality and risk of adult asthma in a prospective cohort study // J. Psychosom. Res. 2015; Jul., 79 (1): 13–17. doi: 10.1016/j.jpsychores.2015.04.002. Epub 2015 Apr 11.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Березин Ф.Б., Мирошников М.П. Русский модифицированный вариант теста MMPI и его применение в психиатрической практике. В кн.: Проблемы психоневрологии. М., 1969: 337.</mixed-citation><mixed-citation xml:lang="en">Loerbroks A., Apfelbacher C.J., Thayer J.F., Debling D., Stürmer T. Neuroticism, extraversion, stressful life events and asthma: a cohort study of middle-aged adults // Allergy. 2009; Oct., 64 (10): 1444–1450. doi: 10.1111/j.1398- 9995.2009.02019.x. Epub 2009 Feb 25.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Березин Ф.Б., Мирошников М.П., Соколова Е.Д. Методика многостороннего исследования личности (структура, основы интерпретации, некоторые обла- сти применения). 3-е изд., испр. и доп. М.: Консуль- тант плюс – новые технологии», 2011: 320 с.</mixed-citation><mixed-citation xml:lang="en">Berezin F.B., Miroshnikov M.P. Russkii modificirovannyi variant testa MMPI i ego primenenie v psihiatricheskoi praktike. V kn.: Problemy psihonevrologii. [Russian modified version of the MMPI test and its application in psychiatric practice. In the book: Problems psychoneurology]. Moscow, 1969: 337 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Bulcun E., Turkel Y., Oguztürk O., Dag E, Buturak S.V., Ekici A., Ekici M. Psychological Characteristics of Patients with Asthma // Clin. Respir. J. 2016; May, 5. doi: 10.1111/crj.12494. [Epub ahead of print].</mixed-citation><mixed-citation xml:lang="en">Berezin F.B., Miroshnikov M.P., Sokolova E.D. Metodika mnogostoronnego issledovaniya lichnosti (struktura, osnovy interpretacii, nekotorye oblasti primeneniya) [Methods multilateral study of personality (structure, based on the interpretation, some applications)]. The third edition (revised and updated). Moscow: Consultant plus – new technologies Publ., 2011: 320 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Лурия Р.А. Внутренняя картина болезни и ятрогенные заболевания. М., 1935.</mixed-citation><mixed-citation xml:lang="en">Bulcun E., Turkel Y., Oguztürk O., Dag E., Buturak S.V., Ekici A., Ekici M. Psychological Characteristics of Patients with Asthma // Clin. Respir. J. 2016; May, 5. doi: 10.1111/crj.12494. [Epub ahead of print]</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Сирота Н.А. Московченко Д.В. Психодиагностика базисных убеждений о болезни (Результаты апробации русскоязычной версии опросника когнитивных представлений о болезни) // Национальный психологический журнал. 2014; 2 (14): 72–81.</mixed-citation><mixed-citation xml:lang="en">Luriya R.A. Vnutrennyaya kartina bolezni i yatrogennye zabolevaniya [Internal picture of illness and iatrogenic disease]. Moscow: 1935 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Овчаренко С.И., Смулевич А.Б., Акулова М.Н. Контроль течения БА: психосоматические соотношения и расстройства личности // Практ. пульмонология. 2009; 1: 22–25.</mixed-citation><mixed-citation xml:lang="en">Sirota N.A. Moskovchenko D.V. Psihodiagnostika bazisnyh ubezhdenii o bolezni (Rezul’taty aprobacii russkoyazychnoi versii oprosnika kognitivnyh predstavlenii o bolezni) [Psychodiagnostics basic beliefs about the disease (results of testing of the Russian version of the questionnaire of cognitive representations of the disease)] // Nacional’nyi psihologicheskii zhurnal – National psychological journal number. 2014; 2 (14): 72–81 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Смулевич А.Б., Овчаренко С.И., Волель Б.А., Воронова Е.И. Психические расстройства у больных с ле- гочной патологией // Психические расстройства в общей медицине. 2015; 2–3: 4–20.</mixed-citation><mixed-citation xml:lang="en">Ovcharenko S.I., Smulevich A.B., Akulova M.N. Kontrol’ techeniia BA: psikhosomaticheskie sootnosheniia i rasstroistva lichnosti [Control of asthma: psychosomatic relations and personality disorders] // Prakt. pul’monologiia – Scient. pulmonology. 2009; 1: 22-25 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Prins L.C., van Son M.J., van Keimpema A.R., van Ranst D., Pommer A., Meijer J.W., Pop V.J. Psychopathology in difficult asthma // J. Asthma. 2015; 52 (6): 587–592. doi: 10.3109/02770903.2014.999281. Epub 2015 Jul 25.</mixed-citation><mixed-citation xml:lang="en">Smulevich A.B., Ovcharenko S.I., Volel’ B.A., Voronova E.I. Psihicheskie rasstroistva u bol’nyh s legochnoi patologiei [Mental disorders in patients with pulmonary pathology] // Psihicheskie rasstroistva v obshei medicine – Mental Disorders in General Medicine. 2015; 2–3: 4–20 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Frieri M., O’Connor M., Nassef M. Asthma, stress and depression in women // Allergy Asthma Proc. 2015; Jul.– Aug., 36 (4): 256–261. doi: 10.2500/aap.2015.36.3847.</mixed-citation><mixed-citation xml:lang="en">Prins L.C., van Son M.J., van Keimpema A.R., van Ranst D., Pommer A., Meijer J.W., Pop V.J. Psychopathology in difficult asthma // J. Asthma. 2015; 52 (6): 587–592. doi: 10.3109/02770903.2014.999281. Epub 2015 Jul 25.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Каган В.Е. Внутренняя картина здоровья и соматические заболевания у детей / Неврозы у детей и под- ростков: тезисы докладов Всесоюзной конференции (Москва, 17–18. XIII. 1986). М., 1986: 74–75.</mixed-citation><mixed-citation xml:lang="en">Frieri M., O’Connor M., Nassef M. Asthma, stress and depression in women // Allergy Asthma Proc. 2015; Jul.– Aug., 36 (4): 256–261. doi: 10.2500/aap.2015.36.3847.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Ананьев В.А. Основы психологии здоровья. Книга 1. Концептуальные основы психологии здоровья. СПб., 2006.</mixed-citation><mixed-citation xml:lang="en">Kagan V. e. Vnutrennyaya kartina zdorov’ya i somaticheskiye zabolevaniya u detey. Nevrozy u detey i podrostkov: Tezisy dokladov Vsesoyuznoy konferentsii [Internal picture of health and somatic diseases in children. Neuroses in children and adolescents: Abstracts of the AllUnion Conference]. Moscow, 17–18 XIII. 1986: 74–75 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Васильев М.А. Диагностика социально-личностных компетенций психосоматического здоровья человека : конструирование и стандартизация мультимодального интегративного опросника МИО-1: автореферат дис. … канд. псих. наук. Санкт-Петербург, 2007.</mixed-citation><mixed-citation xml:lang="en">Anan’yev V.A. Osnovy psikhologii zdorov’ya. Kniga 1. Kontseptual’nyye osnovy psikhologii zdorov’ya [Fundamentals of health psychology. Book 1. Conceptual bases of health psychology]. St.-Petersburg, 2006 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Juniper E.F., O’Byrne P.M., Guyatt G.H., Ferrie P.J., King D.R. Development and validation of a questionnaire to measure asthma control // Eur. Respir J. 1999; Oct., 14 (4): 902–907.</mixed-citation><mixed-citation xml:lang="en">Vasil’yev M.A. Diagnostika sotsial’no-lichnostnykh kompetentsiy psikhosomaticheskogo zdorov’ya cheloveka : konstruirovaniye i standartizatsiya Mul’timodal’nogo Integrativnogo oprosnika MIO-1 [Diagnosis of social and personal competencies of psychosomatic health: design and standardization Multimodal Integrative questionnaire MIQ-1]. Abstract dis. The candidate of psychological sciences: 19.00.04. St-Petersburg, 2007 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Meltzer E.O., Busse W.W., Wenzel S.E. et al. Use of the Asthma Control Questionnaire to predict future risk of asthma exacerbation // J. Allergy Clin. Immunol. 2011; 127: 167–172.</mixed-citation><mixed-citation xml:lang="en">Juniper E.F., O’Byrne P.M., Guyatt G.H., Ferrie P.J., King D.R. Development and validation of a questionnaire to measure asthma control // Eur. Respir J. 1999; Oct., 14 (4): 902–907.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Архипов В.В., Григорьева Е.В., Гавришина Е.В. Контроль над бронхиальной астмой в России: результа- ты многоцентрового наблюдательного исследования НИКА // Пульмонология. 2011; 6: 87–93.</mixed-citation><mixed-citation xml:lang="en">Meltzer E.O., Busse W.W., Wenzel S.E. et al. Use of the Asthma Control Questionnaire to predict future risk of asthma exacerbation // J. Allergy Clin. Immunol. 2011; 127: 167–172.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Juniper E.F., Svensson K., Mörk A.C., Ståhl E. Modification of the asthma quality of life questionnaire (standardised) for patients 12 years and older // Health Qual Life Outcomes. 2005; Sep., 16 (3): 58.</mixed-citation><mixed-citation xml:lang="en">Arkhipov V.V., Grigor’eva E.V., Gavrishina E.V. Kontrol’ nad bronhial’noi astmoi v Rossii: rezul’taty mnogocentrovogo nablyudatel’nogo issledovaniya NIKA [Asthma control in Russia: results of the multicenter observational study NIKA] // Pul’monologiya – Pulmonology. 2011; 6: 87–93 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Hunter M.S. The Women’s Health Questionnaire (WHQ): Frequently Asked Questions (FAQ) // Health Qual. Life Outcomes. 2003; Sep., 10 (1): 41.</mixed-citation><mixed-citation xml:lang="en">Juniper E.F., Svensson K., Mörk A.C., Ståhl E. Modification of the asthma quality of life questionnaire (standardised) for patients 12 years and older // Health Qual Life Outcomes. 2005; Sep., 16 (3): 58.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Астафьева Н.Г., Кусмарцева О.Ф. Оценка качества жизни у женщин фертильного возраста с помощью специального вопросника WHQ. Социология медицины – реформам здравоохранения: материалы Пер- вой всероссийской научно-практической конференции 18–19 июня 2004 г. Волгоград, 2004: 332–335.</mixed-citation><mixed-citation xml:lang="en">Hunter M.S. The Women’s Health Questionnaire (WHQ): Frequently Asked Questions (FAQ) // Health Qual. Life Outcomes. 2003; Sep., 10 (1): 41.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Ware J.E.Jr., Kosinski M., Gandek B., Aaronson N.K., Apolone G., Bech P., Brazier J., Bullinger M., Kaasa S., Leplège A., Prieto L., Sullivan M. The factor structure of the SF- 36 Health Survey in 10 countries: results from the IQOLA Project. International Quality of Life Assessment // J. Clin Epidemiol. 1998; Nov., 51 (11): 1159–1165.</mixed-citation><mixed-citation xml:lang="en">Astaf’yeva N.G., Kusmartseva O.F. Otsenka kachestva zhizni u zhenshchin fertil’nogo vozrasta s pomoshch’yu spetsial’nogo voprosnika WHQ [Quality of life in women of childbearing age using a special questionnaire WHQ]. Sociology medicine – health reform. Proceedings of the First All-Russian scientific-practical conference on 18–19 June 2004. Volgograd, 2004: 332–335 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Новик А.А., Ионова Т.И. Руководство по исследованию качества жизни в медицине. СПб.: Издательский дом «Нева»; М.: «Олма-Пресс Çвездный мир», 2002: 320.</mixed-citation><mixed-citation xml:lang="en">Ware J.E.Jr., Kosinski M., Gandek B., Aaronson N.K., Apolone G., Bech P., Brazier J., Bullinger M., Kaasa S., Leplè- ge A., Prieto L., Sullivan M. The factor structure of the SF-36 Health Survey in 10 countries: results from the IQOLA Project. International Quality of Life Assessment // J. Clin Epidemiol. 1998; Nov., 51 (11): 1159–1165.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Hunter M.S: The Women’s Health Questionnaire (WHQ): the development, standardization and application of a measure of mid-aged women’s emotional and physical health // Quality of Life Res. 2000; 9: 733–738.</mixed-citation><mixed-citation xml:lang="en">Novik A.A., Ionova T.I. Rukovodstvo po issledovaniyu kachestva zhizni v meditsine [Guide to the study of quality of life in medicine]. St.-Petersburg: Publishing house “Neva”; Moscow: Olma-Press Star World Publ., 2002: 320 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Hunter M.S: The Women’s Health Questionnaire (WHQ): the development, standardization and application of a measure of mid-aged women’s emotional and physical health // Quality of Life Res. 2000; 9: 733–738.</mixed-citation><mixed-citation xml:lang="en">Hunter M.S: The Women’s Health Questionnaire (WHQ): the development, standardization and application of a measure of mid-aged women’s emotional and physical health // Quality of Life Res. 2000; 9: 733–738.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
