T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease
https://doi.org/10.20538/1682-0363-2011-1-48-54
Abstract
Aim of the study was to investigate the levels of individual subpopulations of T-regulatory (T-reg) cells in patients with different phenotypes of chronic obstructive pulmonary disease (COPD) with moderate bronchial asthma and healthy volunteers. COPD was associated with increased level of natural (CD4+CD25high) T-cells, while emphysematous phenotype of disease was associated with the highest pool of natural CD4+CD25high. Bronchial asthma was associated with low levels of inducible (CD4+ FoxP3+ ) T-reg.
About the Authors
N. A. Kirillova
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
I. A. Deyev
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
Ye. E. Kremer
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
L. M. Ogorodova
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
G. E. Chernogoryuk
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
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Review
For citations:
Kirillova N.A., Deyev I.A., Kremer Ye.E., Ogorodova L.M., Chernogoryuk G.E. T-regulatory cells subpopulation in bronchial asthma and heterogeneous phenotypes of chronic obstructive pulmonary disease. Bulletin of Siberian Medicine. 2011;10(1):48-54. (In Russ.) https://doi.org/10.20538/1682-0363-2011-1-48-54
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