Clinical aspects of pathogenetic influences defining the immune response in patients with urgent surgical pathology
https://doi.org/10.20538/1682-0363-2011-1-162-167
Abstract
Using methods of factorial analysis the values of the main components (MC) defining a condition of various links of immune system in patients with urgent surgical pathology are calculated. MC interrelations with clinical characteristics describe qualitative structure of the factors influencing the organization of immune system indicators. Results of research can be used for forecasting of diseases current and a choice of effective tactics of treatment.
About the Authors
P. V. Sarap
МУЗ «Городская клиническая больница № 6 им. Н.С. Карповича»
Russian Federation
Russian Federation
Yu. S. Vinnik
Красноярский государственный медицинский университет
Russian Federation
Russian Federation
A. A. Ostanin
НИИ клинической иммунологии СО РАМН
Russian Federation
Russian Federation
References
1. Fung Y.L., Fraser J.F., Wood P. etc. The systemic inflammatory response syndrome induces functional changes and relative hyporesponsiveness in neutrophils / J. Crit. Care. 2008. № 23 (4). P. 542—549.
2. Kaiser H.F. The application of electronic computers to factor analysis // Educational and Psychological Measurement. 1960. № 20. P. 141—151.
3. Oberholzer A., Souza S.M., Tschoeke S.K., Oberholzer C. et al. Plasma cytokine measurements augment prognostic scores as indicators of outcome in patients with severe sepsis // Shock. 2005. № 6. P. 488—493.
4. Rankin J.S., Glower D.D., Teichmann T.L. etc. Immunotherapy for refractory pulmonary infection after adult cardiac surgery: immune dysregulation syndrome / J. Heart Valve Dis. 2005. № 14 (6). P. 783—791.
5. Reith H.B., Rauchschwalbe S.K., Mittelkötter U. etc. IgMenriched immunoglobulin (pentaglobin) positively influences the course of post-surgical intra-abdominal infections / Eur. J. Med. Res. 2004. № 9 (10). P. 479—84.
6. Viswanathan K., Dhabhar F.S. Stress-induced enhancement of leukocyte trafficking into sites of surgery or immune activation / Proc. Natl. Acad. Sci. USA. 2005. № 102 (16). P. 5808—5813.
Review
For citations:
Sarap P.V., Vinnik Yu.S., Ostanin A.A. Clinical aspects of pathogenetic influences defining the immune response in patients with urgent surgical pathology. Bulletin of Siberian Medicine. 2011;10(1):162-167. (In Russ.) https://doi.org/10.20538/1682-0363-2011-1-162-167
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