Association of insertion deletion polymorphism of the ACE gene with factors of circulating rennin-angiotensin-aldosterone system and endothelial function of skin microvassals in preeclampsia
https://doi.org/10.20538/1682-0363-2011-4-32-36
Abstract
The association of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) gene polymorphism with plasma ACE, renin activity and endothelial function of skin microvassals were studied. Preeclamptic patients with the DD genotype of ACE I/D gene polymorphism have lowest plasma renin activity level and endothelium-dependent vasodilatation, D allele carriers have highest plasma ACE activity.
About the Authors
O. V. Radkov
Тверская государственная медицинская академия
Russian Federation
Russian Federation
M. N. Kalinkin
Тверская государственная медицинская академия
Russian Federation
Russian Federation
V. V. Zavarin
Тверская государственная медицинская академия
Russian Federation
Russian Federation
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Review
For citations:
Radkov O.V., Kalinkin M.N., Zavarin V.V. Association of insertion deletion polymorphism of the ACE gene with factors of circulating rennin-angiotensin-aldosterone system and endothelial function of skin microvassals in preeclampsia. Bulletin of Siberian Medicine. 2011;10(4):32-36. (In Russ.) https://doi.org/10.20538/1682-0363-2011-4-32-36
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