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Current neuroimaging modalities in differential diagnosis of radiation-induced brain injury in patients with brain tumors

https://doi.org/10.20538/1682-0363-2011-4-130-136

Abstract

Differentiation of tumor recurrence from radiation-induced brain changes is the main challenge of neuroimaging in patients with treated cerebral tumor. The review presents the limitations of structural imaging and additional opportunities of perfusion imaging techniques, proton magnetic resonance spectroscopy and positron emission tomography in discriminating recurrent tumor from radiation injury.

About the Authors

T. Yu. Skvortsova
Институт мозга человека им. Н.П. Бехтеревой РАН
Russian Federation


Z. L. Brodskaya
Институт мозга человека им. Н.П. Бехтеревой РАН
Russian Federation


Zh. I. Savintseva
Институт мозга человека им. Н.П. Бехтеревой РАН
Russian Federation


References

1. Alexiou G.A., Tsiouris S., Kyritsis A.p. et al. Glioma recurrence versus radiation necrosis: accuracy of current imaging modalities // J. Neorooncol. 2009. V. 95. P. 1—11.

2. Barajas R.F., Chang J.S., Segal M.R. et al. Differentiation of recurrent glioblastoma multiforme from radiation necrosis after external beam radiation therapy with dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging. // Radiology. 2009. V. 253. № 2. P. 489—496.

3. Bobek-Billewicz B., Stasik-Pres G., Majchrzak H., Zarudzki L. Differentiation between brain tumor recurrence and radiation injury using perfusion, diffusion-weighted imaging and MR-spectroscopy // Folia Neuropathol. 2010. V. 48, № 2. P. 81—92.

4. Brandsma D., van den Bent M.J. Pseudoprogression and pseudoresponse in the treatment of gliomas // Curr. Opin. Neurol. 2009. V. 22, № 6. P. 633—638.

5. Burger P.C., Boyko O.B. The pathology of central nervous system radiation injury // Radiation injury to the nervous system / ed. Gutin P.H., Leibel S.A., Sheline G.E. New York: Raven, 1991. P. 191—208.

6. Burger P.C., Mahley M.S.Jr., Dudka L., Vogel F.S. The morphologic effects of radiation administered therapeutically for intracranial gliomas: a postmortem study of 25 cases // Cancer. 1979. V. 44. P. 1256—1272.

7. Chao S.T., Suh J.H., Raja S. The sensitivity and specificity of FDG PET in distinguishing recurrent brain tumor from radionecrosis in patients treated with stereotactic radiosurgery // Int. J. Cancer (Radiat. Oncol. Invest). 2001. V. 96. P. 191—197.

8. Covarrubias D.J., Rosen B.R., Lev M.H. Dynamic magnetic resonance perfusion imaging of brain tumors // The Oncologist. 2004. V. 9. P. 528—537.

9. Hu L.S., Baxter L.C., Smith K.A. et al. Relative cerebral blood volume to differentiate high-grade glima recurrence from posttreatment radiation effects: direct correlation between image-guided tissue histopathology and localized dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging measurements // Am. J. Neuroradiolody. 2009. V. 30, № 3. P. 552—558.

10. Jain R., Narang J., Sundgren P.M. et al. Treatment induced necrosis versus recurrent/progressing brain tumor: going beyond the boundaries of conventional morphologic imaging // J. Neurooncol. 2010. Epub ahead of print. DOI 10.1007/s11060-010-0139-3.

11. Kumar A.J., Leeds N.E., Fuller G.N. et al. Malignant gliomas: MR Imaging spectrum of radiation therapy-and chemotherapy-induced necrosis of the brain after treatment // Radiology. 2000. V. 217. P. 377—384.

12. Langleben D.D., Segall G.M. PET in differentiation of recurrent brain tumor from radiation injury // J. Nucl. Med. 2000. V. 41. P. 1861—1867.

13. Lyubimova N., Hopewell J.W. Experimental evidence to support the hypothesis that damage to vascular endothelium plays the primary role in the development of late radiationinduced CNS injury // The British Journal of Radiology. 2004. V. 77. P. 488—492.

14. Mullins M.E., Barest G.D., Schaefer P.W. et al. Radiation necrosis versus glioma recurrence: conventional MR imaging clues to diagnosis // Am. J. Neuroradiol. 2005. V. 26. P. 1967—1972.

15. Nakajima T., Kumabe T., Kanamori M. et al. Differential diagnosis between radiation necrosis and glioma orogression using sequential proton magnetic resonance spectroscopy and methionine positrin emission tomography // Neurol. Med. Chir. (Tokyo). 2009. V. 49. P. 394—401.

16. Ozsunar Y., Mullins M.E., Kwong K. et al. Glioma recurrence versus radiation necrosis? A pilot comparison of arterial spin-labeled, dynamic susceptibility contrast enhanced MRI, and FDG-PET imaging // Acad. Radiol. 2010. V.

17. № 3. P.282—290. 17. Patronas N.J., Di Chiro G., Brooks R.A. et al. Work in progress: [18F]fluorodeoxyglucose and positron emission tomography in the evaluation of radiation necrosis of the brain // Radiology. 1982. V. 144. P. 885—889.

18. Pružincová Ľ., Steno J., Srbecký M. et al. MR imaging of late radiation therapy- and chemotherapy-induced injury: a pictorial essay // Eur. Radiol. 2009. V. 19. P. 2716—2727.

19. Ricci P.E., Karis J.p., Heiserman J.E. et al. Differentiating recurrent tumor from radiation necrosis: time for reevaluation of positron emission tomography? // Am. J. Neuroradiol. 1998. V. 19, № 3. P. 407—413.

20. Rock J.P., Scarpace L., Hearshen D. et al. Associations among magnetic resonance spectroscopy, apparent diffusion coefficients, and image guided histopathology with special attention to radiation necrosis // Neurosurgery. 2004. V. 54. P. 1111—1119.

21. Sheline G.E., Wara W.M., Smith V. Therapeutic irradiation and brain injury // Int. J. Radiat. Oncol. Biol. Phys. 1980. V. 6. P. 1215—1228.

22. Sundgren P.C. MR spectroscopy in radiation injury // Am. J. Neuroradiol. 2009. V. 30. P. 1469—1476.

23. Terakawa Y., Tsuyuguchi N., Iwai Y. et al. Diagnostic accuracy of 11C-methionine PET for differentiation of recurrent brain tumors from radiation necrosis after radiotherapy // J. Nucl. Med. 2008. V. 49. P. 694—699.

24. Yoshii Y. Pathological review of late cerebral radionecrosis // Brain. Tumor. Pathol. 2008. V. 25. P. 51—58.

25. Zeng Q.S., Li C.F., Zhang K. et al. Multivoxel 3D proton MR spectroscopy in the distinction of recurrent glioma from radiation injury // J. Neurooncol. 2007. V. 84, № 1. P. 63— 69.


Review

For citations:


Skvortsova T.Yu., Brodskaya Z.L., Savintseva Zh.I. Current neuroimaging modalities in differential diagnosis of radiation-induced brain injury in patients with brain tumors. Bulletin of Siberian Medicine. 2011;10(4):130-136. (In Russ.) https://doi.org/10.20538/1682-0363-2011-4-130-136

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ISSN 1682-0363 (Print)
ISSN 1819-3684 (Online)