STUDY OF THE ACTIVITY EXTRACTS FROM SAUSSUREA CONTROVERSA AND FILIPENDULA ULMARIA IN EXPERIMENTAL OSTEOMYELITIS WITH THREE-PHASE SCINTIGRAPHY
https://doi.org/10.20538/1682-0363-2015-3-5-9
Abstract
The activity of extracts from Saussurea controversa DC and Filipendula ulmaria (L.) Maxim studied on experimental osteomyelitis by means of 3-phase scintigraphy. The use of aqueous-ethanolic extracts of the aerial parts of plants helps to reduce the fixation of the radiopharmaceutical in the affected area and what characterizes their positive impact on the disease. These plants are promising objects for study of medicines the treatment of osteomyelitis.
About the Authors
Ye. Yu. Avdeeva
Siberian State Medical University, Tomsk
Russian Federation
Avdeeva Yelena Yu.
Russian Federation
Avdeeva Yelena Yu.
M. A. Zorkaltsev
Siberian State Medical University, Tomsk
Russian Federation
Zorkaltsev Maksim A.
Russian Federation
Zorkaltsev Maksim A.
V. D. Zavadovskaya
Siberian State Medical University, Tomsk
Russian Federation
Zavadovskaya Vera D.
Russian Federation
Zavadovskaya Vera D.
G. V. Slizovsky
Siberian State Medical University, Tomsk
Russian Federation
Slizovsky Grigoriy V.
Russian Federation
Slizovsky Grigoriy V.
Ye. A. Krasnov
Siberian State Medical University, Tomsk
Russian Federation
Krasnov Yefim A.
Russian Federation
Krasnov Yefim A.
V. G. Pekhenko
Institute of Strength Physics and Materials Science, Siberian Branch of the Russian Academy of Sciences, Tomsk
Russian Federation
Pekhenko Vladimir G.
Russian Federation
Pekhenko Vladimir G.
M. Yu. Stepanov
Siberian State Medical University, Tomsk
Russian Federation
Stepanov Mikhail Yu.
Russian Federation
Stepanov Mikhail Yu.
References
1. Beslekoev W.S., Fedoseev M.M., Anipchenko A.N. Vosstanovlenie defektov dlinnyih kostey konechnostey posle ognestrelnyih osteomielitov [The reconstruction of defects of long bones of extremities after gunshot osteomyelitis]. Voenno-meditsinskiy zhurnal – Military Medical Journal, 2005, no. 6, pp. 19–21 (in Russian).
2. Kudaikulov M.K. Posleoperatsionnyiy osteomielit bedra [Postoperative femoral osteomyelitis]. Travmatologiya i ortopediya v Rossii – Traumatology and Orthopedics in Rus- sia, 2006, no. 2, p. 173 (in Russian).
3. Makhson N.Ye. Posttravmaticheskiy osteomielit [Post- traumatic osteomyelitis]. Vrach – The Doctor, 2001, no. 6, pp. 8–10 (in Russian).
4. Stolyarov Ye.A., Batakov Ye.A., Ishutov I.V., Ladonin B.C. Hronicheskiy osteomielit sovremennoe sostoyanie problemyi [Current state of the problem chronic osteomyelitis]. Samarskiy meditsinskiy zhurnal – Samara Medical Journal, 2004, no. 5–6, pp. 28–30 (in Russian).
5. Abaev Yu.K., Protsenko Ye.Yu., Arinchin V.N. Klinicheskaya otsenka perifericheskogo krovoobrascheniya u novorozhdennyih pri osteomielite i artritah [Clinical assess- ment of the peripheral circulation in neonates with osteomyelitis and arthritis]. Detskaya hirurgiya – Pediatric Surgery, 2004, no. 1, pp. 10–13 (in Russian).
6. Batakov Ye.A., Alekseev D.G., Batakov V.Ye. Sovremennyie aspektyi diagnostiki i lecheniya hronicheskogo osteomielita [Modern aspects of diagnosis and treatment of chronic osteomyelitis]. Samara, Medicine Publ., 2008. 117 p.
7. Krasnov Ye.A., Raldugin V.A., Shilova I.V., Avdeeva Ye.Yu. Fenolnyie soedineniya Filipendula ulmaria L. (Maxim) [Phenolic compounds from Filipendula ulmaria]. Himiya prirodnyih soedineniy – Chemistry of Natural Compounds, 2006, no. 2, pp. 122–124 (in Russian).
8. Krasnov Ye.A., Raldugin V.A., Avdeeva Ye.Yu. Vyidelenie i antioksidantnaya aktivnost filimarina – novogo flavonolnogo glikozida iz Filipendula ulmaria [Filimarin: a new flavanol glycoside from Filipendula ulmaria and its antioxidant activity]. Himiko-farmatsevticheskiy Zhurnal – Pharmaceutical Chemistry Journal, 2009, vol. 43, no. 11, pp. 24–25 (in Russian).
9. Churin A.A., Masnaya N.V., Sherstoboev Ye.Yu., Shilova I.V. Vliyanie ekstrakta Filipendula ulmaria na immunnuyu sistemu myishey CBA/CaLac i C57BL/6 [Effect of Filipendula ulmaria extract on the immune system of CBA CaLac and C57BL6 mice]. Eksperimentalnaya i кlinicheskaya farmakologiya – Experimental and Clinical Pharmacology, 2008, vol. 71, no. 5, pp. 32–36 (in Russian).
10. Kudryashov B.A., Lyapina L.A., Kondashevskaya V.M., Kovalchuk G.A. Antikoagulyant iz tavolgi vyazolistnoy, ego antitromboticheskiy i tromboliticheskiy effektyi [An- tithrombotic and thrombolytic effects of Anticoagulant from Meadowsweet]. Vestnik Moskovskogo universiteta – Moscow University Press, 1994, no. 3, pp. 15–17 (in Rus- sian).
11. Avdeeva Ye.Yu., Krasnov Ye.A. Issledovanie elementnogo sostava sossyurei spornoy [The study of the elemental composition of a Saussureа controversa]. Aktualnyie problemyi sovremennoy nauki: materialyi trudov uchastnikov 11-oy mezhdunarodnoy telekonferentsii [Actual problems of mod- ern science: proceedings of papers of participants of the 11th international teleconference], 2013, vol. 2, no. 2, pp. 102–103.
12. Krasnov Ye.A., Avdeeva Ye.Yu., Gorina Yu.V., Shersto- boev Ye.Yu. The composition of biological active substances and pharmacological activity of perspective species flora of Siberia. 4th Annual Russian-Korean Conference “Current Issues of Natural Products Chemistry and Biotechnology”. Novosibirsk, 2012. P. 37.
13. Gorbacheva A.V., Aksenenko S.G., Pashynsky V.G. Labaznik vyazolistnyiy v fitoterapii vospalitelnyih protsessov [Meadowsweet in herbal medicine inflammatory processes]. Tomsk, TGPU Publ., 2005. 305 p.
Review
For citations:
Avdeeva Ye.Yu., Zorkaltsev M.A., Zavadovskaya V.D., Slizovsky G.V., Krasnov Ye.A., Pekhenko V.G., Stepanov M.Yu. STUDY OF THE ACTIVITY EXTRACTS FROM SAUSSUREA CONTROVERSA AND FILIPENDULA ULMARIA IN EXPERIMENTAL OSTEOMYELITIS WITH THREE-PHASE SCINTIGRAPHY. Bulletin of Siberian Medicine. 2015;14(3):5-9. (In Russ.) https://doi.org/10.20538/1682-0363-2015-3-5-9
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