Dithizone injuring action to blood granulocytes and basal parts of intestine crypts
https://doi.org/10.20538/1682-0363-2010-5-24-27
Abstract
It was shown, that dithizone injection to rats induced zinc deficiency in blood granulocytes and Paneth cells. Phase changes of zinc content were observed in the cells. First phase (primary decrease of cytochemically detected zinc content in the cells) was a result of intravital binding of this metal to dithizone. Second one (permanent partial increase of cell zinc content) was a result of decomposition of the product of intravital reaction. Third phase (secondary decrease of cell zinc concentration) was connected with cell necrosis. Dithizone injection to animals also induced cell secretory material deficiency.
About the Authors
Yu. V. Yeschenko
Запорожский национальный университет
Ukraine
Ukraine
V. V. Novitsky
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
V. D. Bovt
Запорожский национальный университет
Ukraine
Ukraine
V. A. Yeschenko
Запорожский национальный университет
Ukraine
Ukraine
O. I. Urazova
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
N. V. Grigorova
Запорожский национальный университет
Ukraine
Ukraine
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Review
For citations:
Yeschenko Yu.V., Novitsky V.V., Bovt V.D., Yeschenko V.A., Urazova O.I., Grigorova N.V. Dithizone injuring action to blood granulocytes and basal parts of intestine crypts. Bulletin of Siberian Medicine. 2010;9(5):24-27. (In Russ.) https://doi.org/10.20538/1682-0363-2010-5-24-27
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