Morphological evaluation of compatibility of ventricular myocardium and external restrictive elastic sac of the original construction made from titanium nickelide after its implantation during the experiment
https://doi.org/10.20538/1682-0363-2010-5-49-54
Abstract
The objective of this study is a morphological evaluation of compatibility of ventricular myocardium with the device of our original construction for restriction of heart chambers dilatation. In the experiment the device made from titanium nickelide was implanted into 8 outbred dogs with the previously induced experimental model of left ventricular aneurism. The animals were excluded from the experiment in 1, 3 and 6 months after implantation of an external restrictive elastic sac. Histological preparations of myocardium samples, which were in an immediate contact with titanium nickelide fibers were the subjects for studying of general tissue response to the presence of an implanted device. No data evidencing negative effect of an external restrictive elastic titanium nickelide sac on ventricular myocardium have been found. It means that an implanted sac has a satisfactory compatibility with biological tissues just as like as any other implant made from titanium nickelide.
About the Authors
V. A. Kazakov
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
A. A. Lezhnev
НИИ кардиологии СО РАМН
Russian Federation
Russian Federation
V. M. Shipulin
НИИ кардиологии СО РАМН
Russian Federation
Russian Federation
Ye. V. Krivoschyokov
НИИ кардиологии СО РАМН
Russian Federation
Russian Federation
I. V. Sukhodolo
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
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Review
For citations:
Kazakov V.A., Lezhnev A.A., Shipulin V.M., Krivoschyokov Ye.V., Sukhodolo I.V. Morphological evaluation of compatibility of ventricular myocardium and external restrictive elastic sac of the original construction made from titanium nickelide after its implantation during the experiment. Bulletin of Siberian Medicine. 2010;9(5):49-54. (In Russ.) https://doi.org/10.20538/1682-0363-2010-5-49-54
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