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Diagnostic aspects of osteopenic syndrome in Type 1 pancreatic diabetes patients

https://doi.org/10.20538/1682-0363-2010-5-165-169

Abstract

The condition of a bone fabric at 102 sick diabetes mellitus type 1 (48 men and 54 women, middle age (38,2 ± 12,2) years) is studied, also are specified influence of various factors on development osteopenic syndrome. Research methods included clinical and history of development of disease, beam, biochemical, statistical methods of processing of results. As a result of research it has been revealed that indicators of bone durability at sick of a diabetes corresponded osteopenia which was accompanied by infringement micro-arhcitecture bones in the form of decrease in relative volume trabecular bones and quantities trabecula. Osteosonographie it was accompanied by changes of markers of a bone metabolism (osteocalcin and C-trailer tilopeptid) testifying to activation of processes osteolysis at sick of a diabetes.

About the Authors

O. S. Tonkikh
МЛПУ «Городская больница № 2»
Russian Federation


Yu. G. Samoilova
Сибирский государственный медицинский университет
Russian Federation


V. D. Zavadovskaya
Сибирский государственный медицинский университет
Russian Federation


Ye. B. Kravets
Сибирский государственный медицинский университет
Russian Federation


O. Yu. Kilina
Сибирский государственный медицинский университет
Russian Federation


L. A. Kriulko
МЛПУ «Городская больница № 2»
Russian Federation


References

1. Килина О.Ю. Возможности метода цифрового анализа компьютерных томограмм в диагностике остеопороза: автореф. дис. … канд. мед. наук. Томск, 2003. 18 с.

2. Alexopoulou O., Jamart J., Devogelaer J.P. et al. Bone density and markers of bone remodeling in type 1 male diabetic patients // Diabetes Metab. 2006. V. 32, № 5. P. 453—458.

3. Chantelau E., Wolf A., Ozdemir S. et al. Bone histomorphology may be unremarkable in diabetes mellitus // Med. Klin. (Munich). 2007. V. 102, № 6. P. 429—433.


Review

For citations:


Tonkikh O.S., Samoilova Yu.G., Zavadovskaya V.D., Kravets Ye.B., Kilina O.Yu., Kriulko L.A. Diagnostic aspects of osteopenic syndrome in Type 1 pancreatic diabetes patients. Bulletin of Siberian Medicine. 2010;9(5):165-169. https://doi.org/10.20538/1682-0363-2010-5-165-169

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ISSN 1682-0363 (Print)
ISSN 1819-3684 (Online)