Diagnostic aspects of osteopenic syndrome in Type 1 pancreatic diabetes patients
https://doi.org/10.20538/1682-0363-2010-5-165-169
Abstract
The condition of a bone fabric at 102 sick diabetes mellitus type 1 (48 men and 54 women, middle age (38,2 ± 12,2) years) is studied, also are specified influence of various factors on development osteopenic syndrome. Research methods included clinical and history of development of disease, beam, biochemical, statistical methods of processing of results. As a result of research it has been revealed that indicators of bone durability at sick of a diabetes corresponded osteopenia which was accompanied by infringement micro-arhcitecture bones in the form of decrease in relative volume trabecular bones and quantities trabecula. Osteosonographie it was accompanied by changes of markers of a bone metabolism (osteocalcin and C-trailer tilopeptid) testifying to activation of processes osteolysis at sick of a diabetes.
About the Authors
O. S. TonkikhRussian Federation
Yu. G. Samoilova
Russian Federation
V. D. Zavadovskaya
Russian Federation
Ye. B. Kravets
Russian Federation
O. Yu. Kilina
Russian Federation
L. A. Kriulko
Russian Federation
References
1. Килина О.Ю. Возможности метода цифрового анализа компьютерных томограмм в диагностике остеопороза: автореф. дис. … канд. мед. наук. Томск, 2003. 18 с.
2. Alexopoulou O., Jamart J., Devogelaer J.P. et al. Bone density and markers of bone remodeling in type 1 male diabetic patients // Diabetes Metab. 2006. V. 32, № 5. P. 453—458.
3. Chantelau E., Wolf A., Ozdemir S. et al. Bone histomorphology may be unremarkable in diabetes mellitus // Med. Klin. (Munich). 2007. V. 102, № 6. P. 429—433.
Review
For citations:
Tonkikh O.S., Samoilova Yu.G., Zavadovskaya V.D., Kravets Ye.B., Kilina O.Yu., Kriulko L.A. Diagnostic aspects of osteopenic syndrome in Type 1 pancreatic diabetes patients. Bulletin of Siberian Medicine. 2010;9(5):165-169. https://doi.org/10.20538/1682-0363-2010-5-165-169