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Adhesion molecules and proinflammatory cytokines in cerebrospinal fluid of multiple sclerosis patients

https://doi.org/10.20538/1682-0363-2009-1(2)-23-26

Abstract

In liquor 30 multiple sclerosis patients with remittent kind of clinical course the concentration of cell-cell adhesion molecules (sPECAM-1, sVCAM-1) and tumor necrosis factor (TNF) α, not interleukin-1β, was higher during the period of exacerbation compared to the period of remission. These changes are supposed to display the activity of pathogenesis important processes multiple sclerosis in cerebral tissue of multiple sclerosis patients.

About the Authors

S. A. Yelchaninova
Алтайский государственный медицинский университет
Russian Federation


I. V. Smagina
Алтайская краевая клиническая больница
Russian Federation


V. A. Sidorenko
Алтайский государственный медицинский университет
Russian Federation


Yu. N. Lichenko
Алтайская краевая клиническая больница
Russian Federation


A. V. Popovtseva
Алтайский государственный медицинский университет
Russian Federation


A. S. Fedyanin
Алтайская краевая клиническая больница
Russian Federation


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Review

For citations:


Yelchaninova S.A., Smagina I.V., Sidorenko V.A., Lichenko Yu.N., Popovtseva A.V., Fedyanin A.S. Adhesion molecules and proinflammatory cytokines in cerebrospinal fluid of multiple sclerosis patients. Bulletin of Siberian Medicine. 2009;8(1(2)):23-26. (In Russ.) https://doi.org/10.20538/1682-0363-2009-1(2)-23-26

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ISSN 1682-0363 (Print)
ISSN 1819-3684 (Online)