Remodeling of the common carotid artery in oncohematological pathology by ultrasound
https://doi.org/10.20538/1682-0363-2018-4-47-53
Abstract
The aim is the assessment of structural and functional state of common carotid artery by ultrasound in patients with non-Hodgkin malignant lymphomas (NHML) before and after chemotherapy.
Materials and methods. The common carotid artery of 111 patients at different stages of NHML were examined via a “LOGIC 400” ultrasound.
Results. The common carotid artery of patients with NHML is undergoing morphological modification with changes in thickness and diameter, which corresponds to a hypertrophic type of remodeling. There is an increase in the thickness of the complex “intima-media” and Kernogan`s index with decreasing the common carotid artery diameter by comparison with the control group. Chemotherapy improves the parameters of the common carotid artery while reducing the thickness of the complex “intima-media” and Kernogan`s index at different stages of NHML.
Conclusion. Remodeling of the common carotid artery is associated with the developmental stage of NHML. Chemotherapy leads to an improvement of the morphological parameters of the common carotid artery, which evaluates the effect of the treatment.
About the Authors
V. D. Koptev
National Research Novosibirsk State University (NRNSU)
Russian Federation
Russian Federation
Koptev Vladimir D., PhD, Associate Professor, Department of Fundamental Medicine
2, Pirogov Str., Novosibirsk, 630090
V. V. Nimaev
Institute of Clinical and Experimental Lymphology (ICEL)
Russian Federation
Russian Federation
Nimaev Vadim V., DM, Head of the Laboratory of Surgical Lymphology and Lymphodetoxication
2, Timakov Str., Novosibirsk, 630060
V. N. Gorchakov
National Research Novosibirsk State University (NRNSU);
Institute of Clinical and Experimental Lymphology (ICEL)
Russian Federation
Russian Federation
Gorchakov Vladimir N., DM, Professor, Head of the Laboratory of Functional Morphology of the Lymphatic System, ICEL; Professor, Department of Fundamental Medicine, NNRSU
2, Pirogov Str., Novosibirsk, 630090,
2, Timakov Str., Novosibirsk, 630060
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Review
For citations:
Koptev V.D., Nimaev V.V., Gorchakov V.N. Remodeling of the common carotid artery in oncohematological pathology by ultrasound. Bulletin of Siberian Medicine. 2018;17(4):47-53. (In Russ.) https://doi.org/10.20538/1682-0363-2018-4-47-53
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