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MORPHOLOGICAL CHARACTERISTICS OF POSTTRAUMATIC SKELETAL MUSCLE REGENERATION AFTER EXPERIMENTAL BLAST INJURY

https://doi.org/10.20538/1682-0363-2015-4-17-24

Abstract

The research objective was a morphological analysis of posttraumatic regeneration of musculoskeletal tissue in rats after experimental blast injury with field simulation of remote musculocutaneous injury of lower limbs. Wound process was evaluated visually and by histological characteristics of injury zones. This research helped to deepen understanding of details of regenerative process of blast musculocutaneous injury and formation of regenerating muscular and connective tissue of skeletal muscle in rats

About the Authors

N. G. Vengerovich
Research Testing Institute (Military Medicine) of S.M. Kirov Military Medical Academy, St. Petersburg
Russian Federation
Vengerovich Nikolay G.


I. A. Shperling
Research Testing Institute (Military Medicine) of S.M. Kirov Military Medical Academy, St. Petersburg
Russian Federation
Shperling Igor A. 


Yu. V. Yurkevich
Research Testing Institute (Military Medicine) of S.M. Kirov Military Medical Academy, St. Petersburg
Russian Federation
Yurkevich Yury V.


O. O. Vladimirova
Research Testing Institute (Military Medicine) of S.M. Kirov Military Medical Academy, St. Petersburg
Russian Federation
Vladimirova Olga O.


I. I. Alekseyeva
Research Testing Institute (Military Medicine) of S.M. Kirov Military Medical Academy, St. Petersburg
Russian Federation
Alekseyeva Irina I.


A. V. Shulepov
Research Testing Institute (Military Medicine) of S.M. Kirov Military Medical Academy, St. Petersburg
Russian Federation
Shulepov Aleksandr V.


S. G. Shchipanov
Research Testing Institute (Military Medicine) of S.M. Kirov Military Medical Academy, St. Petersburg
Russian Federation
Shchipanov Sergey G.


N. V. Shperling
Research Testing Institute (Military Medicine) of S.M. Kirov Military Medical Academy, St. Petersburg
Russian Federation
Shperling Nataliya V.


Ye. V. Romanova
Siberian State Medical University, Tomsk
Russian Federation
Romanova Yelena V.


References

1. Sorokovnikov V.A., Plehanov A.N., Nomokonov I.A. Organizaciya okazaniya medicinskoy pomoshhi postradavshim s tjazhelymi minno-vzryvnymi travmami i ognestrel'nymi raneniyami [The organization of medical aid to the victims of heavy mine-explosive injuries and gunshot wounds]. Byulleten' Vostochno-Sibirskogo nauchnogo centra SO RAMN – Bulletin of the East Siberian Scientific Center, SB RAMS, 2006, pp. 295–297 (in Russian).

2. Nikitaev V.E. Ocenka tyazhesti i prognozirovanie techeniya minno-vzryvnoj travmy. Avtoref. dis. dokt. med. nauk [As-sessment of the severity and prognosis of the mine blast injury. Diss. Dr. med. sci.]. Moscow, 2004. 22 p. (in Russian).

3. Voynovsky Ye.A., Kovalev A.S., Voynovsky A.Ye. Prevari-tel'naya amputaciya konechnosti pri minno-vzryvnoj travme [Prelimb amputation in the mine blast injury]. Medicina katastrof – Disaster Medicine, 2012, no. 1, pp. 38–41 (in Russian).

4. Danilov R.K. Ranevoy process: gistogeneticheskie osnovy [Wound process: histogenetic bases]. St. Petersburg, S.M. Kirov St. Petersburg Military Medical Academy Publ., 2007. 380 p. (in Russian).

5. Odintsova I.A. Regeneracionnyj gistogenez v kozhno-myshechnoy rane (eksperimental'no-gistologicheskoe issledovanie). Avtoref. dis. dokt. med. nauk [Recovery histogenesis in skin-muscle injury (experimental histological study). Diss. Dr. med. sci.]. St. Petersburg, 2004. 34 p. (in Russian).

6. Lili R. Patogistologicheskaya tehnika i prakticheskaya gistohimiya [Histopathological technique and practical histochemistry]. Moscow, Mir Publ., 1969. 648 p. (in Russian).

7. Klishov A.A., Grafova G.Ya., Gololobov V.G. et al. Kletochno-differonnaya organizaciya tkaney i problema zazhivleniya ran [Cellular differons organization of tissues and the problem of wound healing]. Arhiv anatomii, gistologii i jembriologii, 1990, vol. 98, no. 4, pp. 5–23 (in Russian).

8. Danilov R.K., Grigoryan В.А., Gololobov V.G. Eksperimental'no-gistologicheskiy analiz ranevogo processa [Experimental and histological analysis of wound healing]. Voprosy morfologii XXI veka. Vyp. 1. Sb. nauchn. tr., posvjashhennyj 100-letiju kaf. med. biologii SPBGMA im. I.I. Mechnikova. St. Petersburg, I.I. Mechnikov SPbSMA Publ., DEAN Publ., 2008. Pp. 100–104 (in Russian).

9. Odintsova I.A. Sovremennye aspekty gistologicheskogo analiza ranevogo processa [Modern aspects of histological analysis of wound healing]. Voprosy morfologii XXI veka. Vyp. 4. Eds. I.A. Odintsova, S.V. Kostyukevich. St. Petersburg, DEAN Publ., 2015. Pp. 51–53 (in Russian).

10. Danilov R.K., Odintsova I.A. Myshechnaya sistema [Muscu-lar system]. Ed. R.K. Danilov. St. Petersburg, SpecLit Publ., 2011. Vol. 1. Pp. 425–441 (in Russian).

11. Motohashi N., Asakura A. Muscle satellite cell heterogeneity and self-renewal. Front. Cell Dev. Biol., 2014, vol. 30, no. 2. P. 1.

12. Lepper C., Partridge T.A., Fan C.M. An absolute require-ment for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration. Development, 2011, vol. 138, no. 17, pp. 3639–3646.


Review

For citations:


Vengerovich N.G., Shperling I.A., Yurkevich Yu.V., Vladimirova O.O., Alekseyeva I.I., Shulepov A.V., Shchipanov S.G., Shperling N.V., Romanova Ye.V. MORPHOLOGICAL CHARACTERISTICS OF POSTTRAUMATIC SKELETAL MUSCLE REGENERATION AFTER EXPERIMENTAL BLAST INJURY. Bulletin of Siberian Medicine. 2015;14(4):17-24. (In Russ.) https://doi.org/10.20538/1682-0363-2015-4-17-24

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ISSN 1682-0363 (Print)
ISSN 1819-3684 (Online)