Biological markers in risk stratification and progression of cardiovascular disease: present and future
https://doi.org/10.20538/1682-0363-2018-4-264-280
Abstract
Taking into account the increase in the level of cardiovascular diseases in recent decades, the clinician faces the task of attempting to make the fastest possible diagnosis of the pathology at its earliest stages. That is why the aim of our work was to identify the main groups of biological markers, and to separate the role of each of them in the assessment of the risk of development, progression and possible complications of cardiovascular diseases. We have given the main working classification of markers of cardiovascular processes with the allocation of their main types, as well as the basic criteria for the “ideal” biological marker. Finally, an attempt was made to structure biomarkers depending on their molecular mechanisms of pathogenesis in the development of a particular pathology. All these data should help the clinician at the stage of early diagnosis of cardiovascular disease.
About the Authors
V. L. OstankoRussian Federation
Ostanko Valentina L., PhD, Associate Рrofessor, Department of Hospital Therapy with a Course of Rehabilitation, Physiotherapy and Sports Medicine
2, Moscow Trakt, Tomsk, 634050
T. P. Kalacheva
Russian Federation
Kalacheva Tatiana P., PhD, Associate Рrofessor, Department of General Мedical Рractice with a Сourse of Рolyclinic Тherapy
2, Moscow Trakt, Tomsk, 634050
E. V. Kalyuzhina
Russian Federation
Kalyuzhina Elena V., DM, Рrofessor, Department of Hospital Therapy with a Course of Rehabilitation, Physiotherapy and Sports Medicine
2, Moscow Trakt, Tomsk, 634050
I. K. Livshits
Russian Federation
Livshits Inna K., PhD, Associate Рrofessor, Department of Hospital Therapy with a Course of Rehabilitation, Physiotherapy and Sports Medicine
2, Moscow Trakt, Tomsk, 634050
A. A. Shalovay
Russian Federation
Shalovay Alla A., PhD, Associate Рrofessor, Department of Hospital Therapy with a Course of Rehabilitation, Physiotherapy and Sports Medicine
2, Moscow Trakt, Tomsk, 634050
G. E. Chernogoryuk
Russian Federation
Chernogoryuk Georgy E., DM, Рrofessor, Department of Hospital Therapy with a Course of Rehabilitation, Physiotherapy and Sports Medicine
2, Moscow Trakt, Tomsk, 634050
I. D. Bespalova
Russian Federation
Bespalova Inna D., DM, Рrofessor, Department of Hospital Therapy with a Course of Rehabilitation, Physiotherapy and Sports Medicine
2, Moscow Trakt, Tomsk, 634050
R. Sh. Yunusov
Russian Federation
Yunusov Ramil Sh., Оtorhinolaryngologist
9, Alexei Belentsa Str., Tomsk, 634050
L. V. Lukashova
Russian Federation
Lukashova Larisa V., DM, Head of the Department of Infectious Diseases and Eepidemiology
2, Moscow Trakt, Tomsk, 634050
A. P. Pomogaeva
Russian Federation
Pomogaeva Albina P., DM, Рrofessor, Department of Сhildren’s Diseases
2, Moscow Trakt, Tomsk, 634050
A. T. Teplyakov
Russian Federation
Teplyakov Aleksandr T., DM, Рrofessor, Сhief Researcher
111a, Kievskaya Str., Tomsk, 634012
V. V. Kalyuzhin
Russian Federation
Kalyuzhin Vadim V., DM, Рrofessor, Нead of the Department of Hospital Therapy with a Course of Rehabilitation, Physiotherapy and Sports Medicine
2, Moscow Trakt, Tomsk, 634050
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Review
For citations:
Ostanko V.L., Kalacheva T.P., Kalyuzhina E.V., Livshits I.K., Shalovay A.A., Chernogoryuk G.E., Bespalova I.D., Yunusov R.Sh., Lukashova L.V., Pomogaeva A.P., Teplyakov A.T., Kalyuzhin V.V. Biological markers in risk stratification and progression of cardiovascular disease: present and future. Bulletin of Siberian Medicine. 2018;17(4):264-280. (In Russ.) https://doi.org/10.20538/1682-0363-2018-4-264-280