NONINVASIVE EVALUATION OF VASCULAR WALL STIFFNESSIN HEALTHY ADOLESCENTS, THE RISK FACTORS FOR ARTERIAL HYPERTENSION
https://doi.org/10.20538/1682-0363-2015-4-82-86
Abstract
Objective. To evaluate the main indicators characterizing the rigidity of the vascular wall in healthy ado-lescents with such risk factors (RF) for arterial hypertension (AH) as a family history on hypertension and smoking. Identify changes in the initial elastic-elastic properties of the arteries at the preclinical stage of development of hypertension.
Material and methods. It was formed two groups of comparison. Age studied from 13 to 17 years (mean age (15.00 ± 0.31) years). The first group consisted of 30 healthy adolescents whose parents suffer from hypertension from a young age. The second group consisted of 30 healthy smokers teenager from healthy parents. The control group consisted of 30 healthy adolescents from healthy parents. Determines the basic stiffness of the vascular wall: PWV, CAVI, SAI.
Results. A significant in crease in the indicators characterizing the rigidity of the vascular wall in the two comparison groups relative to the control. PWV: 6,89 ± 0,56 (first group), 7.13 ± 0.55 (second group) and 5.5 ± 0.41 (control), p < 0.05.L-CAVI: 5,46 ± 0,39 (first group), 5.84 ± 0.61 (second group) and 4.32 ± 0.41 (control), p < 0.05.R-CAVI: 5,63 ± 0,39 (first group), 5.89 ± 0.56 (second group) and 4.49 ± 0.41(control), p < 0.05. R-AI: 0,89 ± 0,09 (first group), 0.95 ± 0.12 (second group) and 0.62 ± 0.1 (control), p < 0.05.
Smoking teenagers and adolescents with family history of hypertension, there are changes in the initial stiffness of the vessel wall, which requires the allocation of at-riskfor the development of hypertension and prevention activities at the preclinical stage of development ofthe disease.
About the Authors
G. P. Filippov
Siberian State Medical University, Tomsk
Russian Federation
Filippov Gennady P.
Russian Federation
Filippov Gennady P.
K. V. Boronenko
Siberian State Medical University, Tomsk
Russian Federation
Boronenko Kira V.
Russian Federation
Boronenko Kira V.
I. V. Plotnikova
Research Institute for Cardiology, Tomsk
Russian Federation
Plotnikova Irina V.
Russian Federation
Plotnikova Irina V.
Ye. S. Sitkova
Research Institute for Cardiology, Tomsk
Russian Federation
Sitkova Yekaterina S.
Russian Federation
Sitkova Yekaterina S.
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For citations:
Filippov G.P., Boronenko K.V., Plotnikova I.V., Sitkova Ye.S. NONINVASIVE EVALUATION OF VASCULAR WALL STIFFNESSIN HEALTHY ADOLESCENTS, THE RISK FACTORS FOR ARTERIAL HYPERTENSION. Bulletin of Siberian Medicine. 2015;14(4):82-86. (In Russ.) https://doi.org/10.20538/1682-0363-2015-4-82-86
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