FEATURES OF THE INTESTINAL MICROBIOTA IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
https://doi.org/10.20538/1682-0363-2014-5-55-61
Abstract
The article summarizes the results of studies on the composition of microbial communities in stool samples of patients with chronic obstructive pulmonary disease (COPD) compared with healthy volunteers using genome-metagenomic sequencing. It is shown that the microbial community of the intestine in COPD patients is characterized as diverse taxonomic composition of metagenomes that the healthy volunteers microbiota. In this case, the normal composition of intestinal microbiota in patients with COPD is exposed to the qualitative and quantitative modifications. In contrast to healthy volunteers, the intestinal microbiota in patients with COPD is characterized by the presence of representatives of the Proteobacteria, as Citrobacter, Enterobacter, Eggerthella,Proteus, Salmonella, Anaerococcus, Clostridium difficile, Pseudomonas, as well as higher insemination fungus genusCandida (Candida dubliniensis and Candida albicans).
About the Authors
L. M. Ogorodova
Siberian State Medical University, Tomsk
Russian Federation
Ogorodova Lyudmila M.
Russian Federation
Ogorodova Lyudmila M.
V. M. Govorun
Research Institute for Physico-Chemical Medicine, FMBA, Moscow
Russian Federation
Govorun Vadim M.
Russian Federation
Govorun Vadim M.
S. V. Fedosenko
Siberian State Medical University, Tomsk
Russian Federation
Fedosenko Sergei V.
Russian Federation
Fedosenko Sergei V.
M. A. Karnaushkina
A .I. Yevdokimov Moscow State University o f Medicine and Dentistry, Moscow
Russian Federation
Karnaushkina Mariya A.,
Russian Federation
Karnaushkina Mariya A.,
I. V. Saltykova
Siberian State Medical University, Tomsk
Russian Federation
Saltykova Irina V.
Russian Federation
Saltykova Irina V.
D. G. Alekseyev
Research Institute for Physico-Chemical Medicine, FMBA, Moscow
Russian Federation
Alekseyev Dmitry G.
Russian Federation
Alekseyev Dmitry G.
Ye. S. Kostrytikova
Research Institute for Physico-Chemical Medicine, FMBA, Moscow
Russian Federation
Kostryukova Yelena S.
Russian Federation
Kostryukova Yelena S.
A. V. Tyakht
Research Institute for Physico-Chemical Medicine, FMBA, Moscow
Russian Federation
Tyakht Aleksanr V.
Russian Federation
Tyakht Aleksanr V.
A. S. Popenko
Research Institute for Physico-Chemical Medicine, FMBA, Moscow
Russian Federation
Popenko Anna S.
Russian Federation
Popenko Anna S.
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Review
For citations:
Ogorodova L.M., Govorun V.M., Fedosenko S.V., Karnaushkina M.A., Saltykova I.V., Alekseyev D.G., Kostrytikova Ye.S., Tyakht A.V., Popenko A.S. FEATURES OF THE INTESTINAL MICROBIOTA IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE. Bulletin of Siberian Medicine. 2014;13(5):55-61. (In Russ.) https://doi.org/10.20538/1682-0363-2014-5-55-61
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